Protein Alignment Shab and Kcna10

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_001178642.1
• Gene: Kcna10 / 295360
• RGDID: 1304667
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 486
• Identity: 184/486 - (37%)
• Similarity: 264/486 - (54%)
• Gaps: 66/486 - (13%)

  Fly   283 THSRSMSSIP-----PP--EPFMIAQSKAVNSRVSINVGGVRHEVLWRTLERLPHTRLGRLRECT 340
            :|..:.|.||     ||  ||.::.:.   |.||.||:.|:|.|...|||.:.|.|.||
  Rat    58 SHETAFSKIPGEYVDPPGSEPVVLNEG---NQRVIINIAGLRFETQLRTLNQFPETLLG------ 113

  Fly   341 THEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRT-GKLHIVDEMCVLAFSDDLEYWGVDELY 404
            ..|..::..|...   |||||||:..||..||.:|:: ||:.....:.:..|:|::.::   ||.
  Rat   114 DREKRMQFFDSMR---NEYFFDRNRPSFDGILYYYQSGGKIRRPANVPIDVFADEISFY---ELG 172

  Fly   405 LESCCQHKYHQRKENVHEEMRKEAESLRQRDEEEFGEGKCAEYQKYLWELLEKPNTSFAARVIAV 469
            .|:..|.:       ..|...|:.|:|...:          ::.:..|.|.|.|.:|.|||.:||
  Rat   173 SEAMDQFR-------EDEGFIKDPETLLPTN----------DFHRQFWLLFEYPESSSAARGVAV 220

  Fly   470 ISILFIVLSTIALTLNTLP------QLQHIDNGTPQDN----------PQLAMVEAVCITWFTLE 518
            :|:|.:|:|.....|.|||      :|:.:.:.|...|          ....|||:.||.|||.|
  Rat   221 VSVLVVVISITIFCLETLPEFREDRELKVVRDPTINTNKTGLSQTMFTDPFFMVESTCIVWFTFE 285

  Fly   519 YILRFSASPDKWKFFKGGLNIIDLLAILPYFVSL---FLLETNKNATDQFQDVRRVVQVFRIMRI 580
            .:|||...|.|..|||..:||||:::|:|||.:|   .:.||..:|.....  ..::::.|::|:
  Rat   286 LVLRFVVCPSKPDFFKNIMNIIDIISIIPYFATLITELVQETEPSAQQNMS--LAILRIIRLVRV 348

  Fly   581 LRILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFAEKDEKDTKFVSIPETFW 645
            .||.||:|||.|||.||.||:.|.:|||||:.||.:||::|||..||||.||.::.|.|||:.||
  Rat   349 FRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDGFW 413

  Fly   646 WAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNFAEFYKNQMRREKALKRRE 710
            ||.:|||||||||:.|||..||::||:|.|.|||.||||:|:||:||..||..:...|:......
  Rat   414 WAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEKPNIPG 478

  Fly   711 ALDR-----AKREGSIVSFHHINLKDAFAKS 736
            .||:     ..|.||..|.:..|...:..||
  Rat   479 ELDKILNSMGSRTGSTESLNKTNSSRSAEKS 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	37/108 (34%)
		Ion_trans	464..700	CDD:459842	119/254 (47%)
Kcna10	NP_001178642.1	BTB_POZ	86..212	CDD:453885	44/154 (29%)
		Ion_trans	262..467	CDD:459842	104/206 (50%)