Protein Alignment Shab and KCNG2

DIOPT Version :9

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: XP_016881193.1
• Gene: KCNG2 / 26251
• HGNCID: 6249
• Length: 509
• Species: Homo sapiens
• Alignment Length: 469
• Identity: 164/469 - (34%)
• Similarity: 263/469 - (56%)
• Gaps: 42/469 - (8%)

  Fly   270 THSQSNTTGALQRTHSRSMSSIPPP----EPFMIAQSKAVNSR---VSINVGGVRHEVLWRTLER 327
            |.|....|..|.|..||:.:....|    ||:..:......:|   |.|||||.|..:.|..|.|
Human    16 TGSLKENTLYLHRARSRAGAPRSGPALRMEPWPCSPGGGGGTRARHVIINVGGCRVRLAWAALAR 80

  Fly   328 LPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFS 392
            .|..||.|||.|..|:.::.:||||.::.:|:||||.|.:|.:|:...|.|||.::...|.|||.
Human    81 CPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFR 145

  Fly   393 DDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKEAESLRQRDEEEFGEGKCAEY---------- 447
            |:|.|||:||..||.||..:..:|:|        ||...|....|...:|..|..
Human   146 DELAYWGIDEARLERCCLRRLRRREE--------EAAEARAGPTERGAQGSPARALGPRGRLQRG 202

  Fly   448 QKYLWELLEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQLQHIDNGTPQDNPQ---LAMVEA 509
            ::.|.::::.|::..|.::.|.:|:.|:.::.:.|.|:|:|.:: .:....:.:|:   |.::|.
Human   203 RRRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDIR-AEEERGECSPKCRSLFVLET 266

  Fly   510 VCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLFL-LETNKNATDQFQDVRRVVQ 573
            ||:.||:.|::||...:..|..|.:..|||||:||:||::|||.| |......|...:....|::
Human   267 VCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLGLAAGPGGTKLLERAGLVLR 331

  Fly   574 VFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFAEKD---EKDT 635
            :.|.:|:|.:::|||||.||:|||.|:|...:|.|||:|||.:.:.:|:.|.:.||::   .:|
Human   332 LLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRD- 395

  Fly   636 KFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNFAEFY---K 697
             |.|:|.::|||.|:||||||||:.|.:..|:|:.....:.|:|::|.|:..|.:.|:..|   |
Human   396 -FSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELK 459

  Fly   698 NQMRR----EKALK 707
            .|.:|    |.||:
Human   460 EQQQRAASPEPALQ 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB	309..416	CDD:197585	49/106 (46%)
		BTB_2	309..408	CDD:280393	47/98 (48%)
		Ion_trans	501..700	CDD:278921	81/208 (39%)
		Ion_trans_2	613..696	CDD:285168	31/85 (36%)
KCNG2	XP_016881193.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11537
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920