Protein Alignment Shab and Kcng1

DIOPT Version :9

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_001074603.1
• Gene: Kcng1 / 241794
• MGIID: 3616086
• Length: 514
• Species: Mus musculus
• Alignment Length: 455
• Identity: 172/455 - (37%)
• Similarity: 280/455 - (61%)
• Gaps: 31/455 - (6%)

  Fly   279 ALQRTHSRSMSSIPPPEPFMIAQSKAVNSR---VSINVGGVRHEVLWRTLERLPHTRLGRLRECT 340
            |::....|....:.|.:.  :.||.::..|   :.|||||:::.:.|.||:..|.||||:|:.||
Mouse    34 AIKGVFYRRAQRLRPQDD--LHQSCSLGDRRRQIIINVGGIKYSLPWTTLDEFPLTRLGQLKACT 96

  Fly   341 THEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYL 405
            ..:.|:.:||||.:..||:||||:|.:|.:||.|.|.|||.::.|||.|:|.::|.|||:.|.:|
Mouse    97 NFDDILSVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHL 161

  Fly   406 ESCCQHKYHQRKENVHEEMRKEAES--LRQRDEEEFG----EGKCAEYQKYLWELLEKPNTSFAA 464
            :.||:.:|.|:.|...|.|.:|.|.  |...|:|..|    ||:.:...:.|.:::|:|::....
Mouse   162 DGCCKRRYLQKIEEFAEMMEREEEEEPLDSEDQESEGPSASEGRLSRCMRRLRDMVERPHSGLPG 226

  Fly   465 RVIAVISILFIVLSTIALTLNTLPQLQHIDNGTPQDNPQLA-------MVEAVCITWFTLEYILR 522
            :|.|.:|:||:.::.:.|:::|||.|:.     .::..|.:       :||:||:.||:||::||
Mouse   227 KVFACLSVLFVTVTAVNLSVSTLPSLRE-----EEEQGQCSQMCHNVFIVESVCVGWFSLEFLLR 286

  Fly   523 FSASPDKWKFFKGGLNIIDLLAILPYFVSLFL----LETNKNAT-DQFQD-VRRVVQVFRIMRIL 581
            |..:|.|:.|.:..|.:|||:|||||:|:|.:    ....|.:| :.:.| |..|::|.|.:|||
Mouse   287 FIQAPSKFAFLRSPLTLIDLVAILPYYVTLLVDGAASSRRKPSTGNSYLDKVGLVLRVLRALRIL 351

  Fly   582 RILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFAEKDEKDT-KFVSIPETFW 645
            .:::|||||.|||:||.|.|...:|.|||:|||.:.:.:|:.|.|..|.:..|: :|.|||..:|
Mouse   352 YVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYW 416

  Fly   646 WAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNFAEFY-KNQMRREKALKRR 709
            ||.||||||||||:.|.:..|:|:.....:.|:|::|.|:..|.:.|:..| :.:..:|:.|.||
Mouse   417 WAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVLIRR 481

  Fly   710  709
            Mouse   482  481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB	309..416	CDD:197585	50/106 (47%)
		BTB_2	309..408	CDD:280393	47/98 (48%)
		Ion_trans	501..700	CDD:278921	87/213 (41%)
		Ion_trans_2	613..696	CDD:285168	33/83 (40%)
Kcng1	NP_001074603.1	BTB_POZ_KCNG1_2	60..173	CDD:349728	52/112 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	180..205		8/24 (33%)
		Ion_trans	227..471	CDD:395416	97/248 (39%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	424..429		4/4 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11537
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910