Protein Alignment Shab and Kcnv2

DIOPT Version :9

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_899002.1
• Gene: Kcnv2 / 240595
• MGIID: 2670981
• Length: 562
• Species: Mus musculus
• Alignment Length: 548
• Identity: 192/548 - (35%)
• Similarity: 298/548 - (54%)
• Gaps: 63/548 - (11%)

  Fly   232 PVASP-THSIPTT-SQQIVGSVGGVGVGGASSQSISGGVPTHSQSNTTG---------------- 278
            |.::| |..:|.| |.|...|:..:|....|..||:   |..::.|...
Mouse    16 PWSTPETEDVPNTGSNQHRRSICSLGARTGSQASIA---PQWTEGNYNYYIEEDEDCGEEGEDWK 77

  Fly   279 ---ALQRTHSRSMSSIPPPEPFMIAQSKAVNSRVSINVGGVRHEVLWRTLE--RLPHTRLGRLRE 338
               |.:...:..::|:........||.    |.:.:||||  |..|....|  ..|.||||||..
Mouse    78 DDLAEENQKAECLTSLLDGHNDTPAQM----STLKVNVGG--HSYLLECCELANYPKTRLGRLAT 136

  Fly   339 CTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDEL 403
            .||....:.|||||....:||||||.|..|..|.|||.:|.|.:.||:|..:|.::|.||||...
Mouse   137 STTRRGQLGLCDDYEAQTDEYFFDRDPAVFQLIYNFYTSGVLLVRDELCPRSFLEELGYWGVRLK 201

  Fly   404 YLESCCQHKYHQRKENVHEEMRKEAESLRQRDEEEFGEGKCAEYQKY------LWELLEKPNTSF 462
            |...||:..:.:|::.:.|:::.:.| ||.:.:.|..|....:.:.|      ||.|:|||.:|.
Mouse   202 YTPRCCRICFEERRDELSEQLKIQRE-LRAQAQAEEAEELFRDMRFYGPQRQRLWNLMEKPFSSV 265

  Fly   463 AARVIAVISILFIVLSTIALTLNTLPQLQH-IDNGTPQDNPQ--LAMVEAVCITWFTLEYILRFS 524
            ||:.:.|.:.||:::|.:||.|||:.::|| .:.||...:|:  |..||.:|:.:||||::||.:
Mouse   266 AAKAMGVATNLFVLISVVALALNTVEEMQHQAEQGTGGGDPRPILEHVEMLCVAFFTLEFLLRLA 330

  Fly   525 ASPDKWKFFKGGLNIIDLLAILPYFVSL----FLLETNKNATDQFQD-----------VRRVVQV 574
            ::|:..:|.:..||::||:||||:::.|    |..|..::..|..::           |.:|:::
Mouse   331 STPNLQRFARSALNLVDLVAILPFYLQLLLECFTSEDQRHNKDSPREHDLETVGRVGKVGQVLRI 395

  Fly   575 FRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFAEKDEKDTKFVS 639
            .|:|||.||||||||||||::.|||||..|:::|.||||:.||:..||:..|..|.|...|.|.|
Mouse   396 MRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLMLFITMGIFSFSAAVYSVEHDVPGTNFTS 460

  Fly   640 IPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNFAEFYKNQMRREK 704
            |...:|||.::::||||||:||.|.||::...:|...|:::..:||.|:.|.|:::|......|.
Mouse   461 ILHAWWWAAVSISTVGYGDMYPETHLGRLFAFLCIAFGIILNGMPISILYNKFSDYYSKLKAYEY 525

  Fly   705 ALKRREA-----LDRA-KREGSIVSFHH 726
            ...|||.     :.|| |:....:|..|
Mouse   526 TAIRRERGKVNFMQRATKKMAECLSESH 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB	309..416	CDD:197585	47/108 (44%)
		BTB_2	309..408	CDD:280393	45/100 (45%)
		Ion_trans	501..700	CDD:278921	87/215 (40%)
		Ion_trans_2	613..696	CDD:285168	33/82 (40%)
Kcnv2	NP_899002.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		7/17 (41%)
		BTB	107..198	CDD:197585	42/92 (46%)
		BTB	107..198	CDD:295341	42/92 (46%)
		Ion_trans	305..521	CDD:278921	87/215 (40%)
		Ion_trans_2	434..509	CDD:285168	30/74 (41%)
		Selectivity filter. /evidence=ECO:0000250	474..479		4/4 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11537
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920