Protein Alignment Shab and twk-7

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_498903.3
• Gene: twk-7 / 192073
• WormBaseID: WBGene00006662
• Length: 557
• Species: Caenorhabditis elegans
• Alignment Length: 564
• Identity: 113/564 - (20%)
• Similarity: 179/564 - (31%)
• Gaps: 223/564 - (39%)

  Fly   316 VRHEVLWRTLERLPHTRLGR---------LREC--TTHEAIVELCDDYSLADNEYFFDRHPKSFS 369
            :|.|.|:.  |.:....|||         :..|  :.||.|.:..||.|..::|...:...:.|:
 Worm    97 LRREALFG--EEVTRAGLGRAEYYEDSHLIHSCDKSGHEDIDDESDDESKDEDEEEEETGIRKFA 159

  Fly   370 SI-------------------LNFYRTGKLH---IVDEMCVLAFSDDLEYWGVDELYLESCCQHK 412
            .:                   |.||...:.|   :.::...|.::...|:  ||:|.
 Worm   160 KLVLPHVALVLLTCTYTVIGALIFYSVEQPHEQMMKEQQLKLIYTRQNEF--VDDLI-------- 214

  Fly   413 YHQRKENVHEEMRKEAESLRQRDEEEFGEGKCAEYQKYLWELLE-KPNTS-----------FAAR 465
               |....:|..|.|.|||.:|......:.....::||.....| |.|.:           ||..
 Worm   215 ---RLAAGNETKRYEWESLAERHMHNMSDQLFVAFEKYFLTSNEVKKNAATETWTFSSSIFFAVT 276

  Fly   466 VIAVIS---------------ILFIVLSTIALTLNTLPQL-----QHIDNGTPQDNPQLAMVEAV 510
            |:..|.               |||.:|. |.|||.|:..|     :|
 Worm   277 VVTTIGYGNPVPVTNIGRIWCILFSLLG-IPLTLVTIADLGKFLSEH------------------ 322

  Fly   511 CITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLFLLETNKNATDQFQDVRRVVQVF 575
             :.|....|:        |.|:.               .:|....|..::..:..
 Worm   323 -LVWLYGNYL--------KLKYL---------------ILSRHRKERREHVCEHC---------- 353

  Fly   576 RIMRILRILKLARHSTGLQSLGFTLRNSYKE------LGLLMLFLAMGVLIFSSL---AYFAEKD 631
                         ||.|   :|..:....|.      |.:|:::.|.|.::.|.|   ::|.
 Worm   354 -------------HSHG---MGHDMNIEEKRIPAFLVLAILIVYTAFGGVLMSKLEPWSFFT--- 399

  Fly   632 EKDTKFVSIPETFWWAGITMTTVGYGDIYPT-----------TALGKVIGTVCC-ICGVLVI--- 681
                       :|:|:.|||||||:||:.|.           ..||..|.|:|. :.||..|
 Worm   400 -----------SFYWSFITMTTVGFGDLMPRRDGYMYIILLYIILGLAITTMCIDLVGVQYIRKI 453

  Fly   682 ------------ALPI----PIIVNNFAEFYKNQMRREKALKRREALDRAKREGSIVSFHHINLK 730
                        ||.:    .::|   :|.|.|.|::......|||.   ..|...||.|.|...
 Worm   454 HYFGRKIQDARSALAVVGGKVVLV---SELYANLMQKRARNMSREAF---IVENLYVSKHIIPFI 512

  Fly   731 DAFAKSMDLIDVIVDTGKQTNVVHPKGKRQSTPNIGRQTLDVQS 774
            ....:.:..||...|.              :|.:.....:|:||
 Worm   513 PTDIRCIRYIDQTADA--------------ATISTSSSAIDMQS 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	25/130 (19%)
		Ion_trans	464..700	CDD:459842	57/295 (19%)
twk-7	NP_498903.3	Ion_trans_2	<265..321	CDD:462301	14/56 (25%)
		Ion_trans_2	373..>422	CDD:462301	19/62 (31%)