Protein Alignment Shab and kvs-1

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_001360715.1
• Gene: kvs-1 / 183753
• WormBaseID: WBGene00002242
• Length: 499
• Species: Caenorhabditis elegans
• Alignment Length: 502
• Identity: 155/502 - (30%)
• Similarity: 255/502 - (50%)
• Gaps: 84/502 - (16%)

  Fly   240 IPTTSQQIVGSVGGVGVGGASSQSISGGVPTHSQSNTTGALQRTHSRSMSSIPPPEPFMIAQSKA 304
            ||:|.:           |.|:|:...|....|...    .:.|.::...|.|...:|.::  |.|
 Worm    21 IPSTRK-----------GHAASRDNFGNSNHHGDE----IVHRLNNGRRSEIDEVKPDLV--SGA 68

  Fly   305 VNSRVSINVGGVRHEV-LWRTLERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSF 368
            .::.:.:||||....: :.....|....:|....: ..||..::.||.:.:...||:.:|....|
 Worm    69 GDTVIKLNVGGTSFRIRISSIFARSADEKLSAFAQ-LNHEQRLQACDAFLMPQEEYYLERSAVLF 132

  Fly   369 SSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYH------------QRKENVH 421
            .||..:|.:|:||...::|...|:.:|.||.:::..:.:||...|:            ::|..:|
 Worm   133 DSIFKYYISGQLHRPLDVCPTEFATELAYWKINDGLMSNCCWRGYNMSPSLEELVAPKEKKIELH 197

  Fly   422 EEMRKEAESLRQRDEEEFGEGKCAEYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIALTLNT 486
            :      .|:|.| ..:|.||                :.|..:.:....||.|:::|.|.|.|.:
 Worm   198 D------RSMRSR-IHQFCEG----------------DGSLFSTLFTFGSITFVLISVIGLVLGS 239

  Fly   487 LPQLQ------------------HIDNGTP----------QDNPQLAMVEAVCITWFTLEYILRF 523
            :.:.|                  ...|||.          :.:|....||.|||.|||:|:|:|.
 Worm   240 IHEFQVPIYKKGGKSERISNWSIADQNGTDSSVENENIIWEPHPIFGYVETVCIIWFTVEFIVRL 304

  Fly   524 SASPDKWKFFKGGLNIIDLLAILPYF--VSLFLLETNKNATDQFQDVRRVVQVFRIMRILRILKL 586
            :.:|::::|..|.:||:|::||:|::  :.|.|...:..:....:....||:|.|::|::|||||
 Worm   305 AVTPNRFQFLVGIMNIVDMIAIIPFYLELGLALFGIDVASLSDIKGALLVVRVLRVLRVVRILKL 369

  Fly   587 ARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFAEKDEKDTKFVSIPETFWWAGITM 651
            .|:|:|:::...||::|.::||::.:.|:.||:.||:|.||.|||||||.|.|||..||||.:||
 Worm   370 GRYSSGMRTFALTLKSSARQLGMMGMVLSTGVVFFSTLLYFVEKDEKDTPFTSIPAAFWWAIVTM 434

  Fly   652 TTVGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNFAEFYKN 698
            |||||||..|.|..||:|.:...|.||||:||||.|||:||.:...|
 Worm   435 TTVGYGDYVPVTVPGKLIASGAIISGVLVLALPITIIVDNFMKVSGN 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	27/108 (25%)
		Ion_trans	464..700	CDD:459842	104/265 (39%)
kvs-1	NP_001360715.1	BTB_POZ_Kv	73..163	CDD:349626	24/90 (27%)
		Ion_trans	279..475	CDD:459842	90/195 (46%)