Protein Alignment Shab and kqt-2

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_509392.3
• Gene: kqt-2 / 181078
• WormBaseID: WBGene00002234
• Length: 695
• Species: Caenorhabditis elegans
• Alignment Length: 755
• Identity: 141/755 - (18%)
• Similarity: 247/755 - (32%)
• Gaps: 250/755 - (33%)

  Fly   418 ENVHEEMRKEAESLRQRDEEEFGEGKCAEYQKY---LWELLEKPNTSFAARVIAVISILFIVLST 479
            ::..:...:.::::|:|.....|..:....::.   ::..||||..  ||.......|..:|::.
 Worm    45 DDAEDSETEVSDNIRRRSTINLGNQRQRNLRRIRLKVYNFLEKPLN--AASAPYHFFIFGLVIAN 107

  Fly   480 IALTLNTLPQLQHIDNGTPQDNPQLA-----MVEAVCITWFTLEYILR-FSASPD-KWKFFKGGL 537
            |.|...|            .||....     .:|...|.:|.||:.:| :|...| |::...|.|
 Worm   108 IILGAAT------------NDNDSTVSKIHFFLEIFMIVFFILEFAVRLWSVRADAKYRTKYGRL 160

  Fly   538 -------NIIDLLAILPYFVSLFLLETNKNATDQFQDVRRVVQVFRIMRILRIL---KLARHSTG 592
                   .:||:| |:|..: |.|:....:......|..|.:|:.|:..:.|.:   ||.|.
 Worm   161 YYLFHTVTLIDIL-IIPATI-LLLVFKGHDVDGSTLDTLRFIQILRLFHVDRQMATWKLLRK--- 220

  Fly   593 LQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFAE---------------KDEKDTKFVSIPE 642
                 ..:...::.:....:.|.:| |..:::.|..|               .:..:..|.::..
 Worm   221 -----MIILGKWQLMATYYITLVVG-LSLATIVYSTEALAQGIQDNGYGLIVPEGTNATFPTMAH 279

  Fly   643 TFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLV----------IALPIPIIVNNFAEFYK 697
            ::|:..:|:.|||||||||..||.|.:   .|:.|.:.          |::.:.:::.   |..|
 Worm   280 SWWFTAVTVMTVGYGDIYPVGALTKFL---VCVLGFIAFCTFQAANTQISVGLTLMME---EENK 338

  Fly   698 NQMR---REKALK------RREALDRAKREGSIVSFHHINLKDAFAKSMDLIDVIVDTGKQTNVV 753
            ||..   |..|..      |.......|.......|.|:..|         :.|..:...|..|:
 Worm   339 NQQTNRLRNLAASTIQCWWRYHLATNWKPPRRYTYFVHVCYK---------LYVTEERINQNRVL 394

  Fly   754 HPKGKRQSTPNIGRQTLDVQSAPGHNLSQTDGNSTEGE----STSG-RNPATTGTGCYKNYDHVA 813
            ..|         .|:.|: :..|....|.|..||...|    ...| ..|.......:...:...
 Worm   395 AKK---------LREKLE-KKRPIKKKSLTHQNSVTAEILKFGFKGMAKPMLEKQDSFDKAERKI 449

  Fly   814 NLRNSNLHNRRGSSSEQDAVPPYSFDNPNARQTSMMAMESYRREQQALLQQQQQQQQQMLQMQQI 878
            :||.:...:||.|..:..||.     :|..|:..:.|
 Worm   450 SLRRTRSEDRRSSLPDTLAVV-----DPAIRKRVLFA---------------------------- 481

  Fly   879 QQKAPNGNGGATGGGVANNLAMVAASSAATAVATATNASNASNTAPGSEGAEGGGDGDGGGVDDD 943
              :|.|                   ||..|:::::.:.|........:...|         .:.|
 Worm   482 --EARN-------------------SSVETSMSSSVDVSELETQFEITNFLE---------QNVD 516

  Fly   944 NLSQAKGLPIQMMI-------------------------TPGEVAELRRQVA-LENLQNQRMDNL 982
            .|| :|.:.|.::|                         ..|::..:..::| .||.:||:|..|
 Worm   517 ELS-SKEVDISLLIKYRPLLRFYYFVMFRFIMNKFHTQRIAGQLLMIEAEIAERENQRNQKMKEL 580

  Fly   983 EQDV----------PVE-----------FECCFCTTKDFKEFTDAEGVISLPTSDFHKPICLEMR 1026
            |..:          |.:           .|.|....:|.:..|||...|::.        ||.:.
 Worm   581 EAAILELTGKPTVSPFDDSGQKLSIIERLEFCEKRMEDLERKTDALNEITIK--------CLNLM 637

  Fly  1027 L----AAAGRQAGAYGLLSPLPAPLPPLHGPLLALPPPPP 1062
            :    .||.|.....|                  |||.||
 Worm   638 MMDTQEAASRTKDEQG------------------LPPKPP 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720
		Ion_trans	464..700	CDD:459842	60/277 (22%)
kqt-2	NP_509392.3	Ion_trans	96..318	CDD:459842	55/247 (22%)