Protein Alignment Shab and exp-2

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_001367760.1
• Gene: exp-2 / 179003
• WormBaseID: WBGene00001374
• Length: 510
• Species: Caenorhabditis elegans
• Alignment Length: 515
• Identity: 179/515 - (34%)
• Similarity: 277/515 - (53%)
• Gaps: 63/515 - (12%)

  Fly   234 ASPTHSIPTTSQQIVGSVGGVGVGGASSQSISGGVPTHSQSNTTGALQRTHS------RSMSSIP 292
            ||.::|....:.|:.|::    :.||:.|.....||.......|.|.:|.:.      ||.:|
 Worm     4 ASISYSALAYNGQVTGNM----ISGAAQQHKKRLVPLRRTDAMTVAERRNYQILDDIFRSGAS-- 62

  Fly   293 PPEPFMIAQSKAVNSR--VSINVGGVRHEVLWRTLERLPHTR-LGRLRECTTHEAIVELCDDYSL 354
              :.|....|....|.  :.:|:||....:|...:.|...|. |.|..: .||.|.:::.|.|..
 Worm    63 --DCFQQVSSADNGSPQFLKLNIGGTSFMILIDAILRADTTTFLSRFVQ-LTHTARLKVADAYIS 124

  Fly   355 ADNEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKEN 419
            ||:.|:|.|.|.||.::..:|.||.:|...|:|..:|..:|::|.:...::.|||.....|::|
 Worm   125 ADDAYYFQRSPTSFEAVFQYYATGVVHRPSEICPASFLSELDFWRISHQHVGSCCADIIPQKRE- 188

  Fly   420 VHEEMRKEAESLRQRDEEEFGEGKCAEYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIALTL 484
              ||  ||.|.:   |:..|.:..|.:.::.:|..||:|.:|..|:...:.|.||:.:|.:.|:.
 Worm   189 --EE--KEEEKV---DDTTFDKLMCGKLRRRMWTFLERPGSSMQAKAFELSSTLFVAISVMGLSF 246

  Fly   485 NTLPQLQ-------H-----IDNGTPQ----------DNPQLAMVEAVCITWFTLEYILRFSASP 527
            .|:|..|       |     :.|||..          ::|.....|.:||.:||:||.|||.|:|
 Worm   247 GTIPDFQVTHLMPPHNETVVLPNGTVTVVQKVEQMRVEHPAFVFTERICIAFFTVEYCLRFFAAP 311

  Fly   528 DKWKFFKGGLNIIDLLAILPYFVSLFLLETNKNATD-QFQDVR---RVVQVFRIMRILRILKLAR 588
            .|.:|....||::|||||:|:::.|.|  |.....| :.:|:|   .||::.|::|::||:||.|
 Worm   312 RKLRFALKPLNLVDLLAIVPFYLELLL--TLCGVDDRKLRDLRWAFLVVRILRVLRVIRIIKLGR 374

  Fly   589 HSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFAEKDEKDTKFVSIPETFWWAGITMTT 653
            .|:|||:.|.||:.|.|:|.::.:.|..||:.||::.||.||||:.|.|.|||..:||..:||||
 Worm   375 FSSGLQTFGMTLQRSQKQLQMMTIVLLTGVVFFSTMIYFLEKDEEGTPFTSIPAAYWWCIVTMTT 439

  Fly   654 VGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNF---------AEFYKNQMRREK 704
            |||||..|.|.:||:|.:...:|||||:||||.|||:||         ||..||..:.|:
 Worm   440 VGYGDAVPATTMGKIIASAAIMCGVLVLALPITIIVDNFIKVAQDEQQAEQQKNDQQSEQ 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	34/110 (31%)
		Ion_trans	464..700	CDD:459842	111/270 (41%)
exp-2	NP_001367760.1	BTB_2	79..178	CDD:426665	30/99 (30%)
		Ion_trans	292..478	CDD:459842	91/187 (49%)