Protein Alignment Shab and shl-1

DIOPT Version :9

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_500975.2
• Gene: shl-1 / 177400
• WormBaseID: WBGene00022240
• Length: 578
• Species: Caenorhabditis elegans
• Alignment Length: 614
• Identity: 186/614 - (30%)
• Similarity: 292/614 - (47%)
• Gaps: 114/614 - (18%)

  Fly   288 MSSIPPPEPFMIAQSKAV------NSRVSINVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIV 346
            :|..|.|:..:..|:|.:      :.:::||:.|.|.|....|||:.|.|.||      ::|...
 Worm    21 ISRQPMPQAPVAIQAKDLAVDHVSDEKLAINISGRRFETWKNTLEKFPETLLG------SNEKEF 79

  Fly   347 ELCDDYSLADNEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQH 411
            ...:|    ..||||||.|..|..||.||||||||.....|::|:.::|.::|:....:..||..
 Worm    80 FYDED----TGEYFFDRDPDIFRHILTFYRTGKLHYPRHECLVAYDEELSFFGIMPDLISDCCYE 140

  Fly   412 KYHQRKENVHEEMRKEAESLRQRDEEEFGEGKCAEYQKYLWELLEKPNTSFAARVIAVISILFIV 476
            .|..:|....|.:::|     :.:..:....|.:..:| :|...|.|:|:..|.|...:...||.
 Worm   141 DYKDKKRENQERLQEE-----RVENADISTLKLSLKEK-MWAAFENPHTTSIALVFYYVIGFFIA 199

  Fly   477 LSTIALTLNTLPQLQHIDN-----GTPQDNPQLAMVEAVCITWFTLEYILRFSASPDKWKFFKGG 536
            :|.:...:.|:| ..:.||     |...:. |..:::..|:..||:||.||..::||:.||.:..
 Worm   200 VSVMCNIVETIP-CGYEDNVSVTCGEAYEE-QFFVIDTACVIIFTIEYFLRLISAPDRIKFMRSI 262

  Fly   537 LNIIDLLAILPYFVSLFLLETNKNATDQFQDVRRVVQVFRIMRILRILKLARHSTGLQSLGFTLR 601
            :::||::||:||:|||.|       ||. :||..:....|:.|:.||.|.:|||.||:.||:||:
 Worm   263 MSVIDVIAIMPYYVSLVL-------TDN-KDVSGLFVTLRVFRVFRIFKFSRHSQGLRILGYTLK 319

  Fly   602 NSYKELGLLMLFLAMGVLIFSSLAYFAEKDEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALG 666
            :...|||.|:..|||.::||:::.|:|||....|:|.|||..||:..:|:||:||||:.|:|.:|
 Worm   320 SCASELGFLVFSLAMAIIIFATIMYYAEKKVDATRFTSIPSAFWYTIVTLTTLGYGDMVPSTIMG 384

  Fly   667 KVIGTVCCICGVLVIALPIPIIVNNFAEFYKNQMRREKALKRREA-LDR---AKREGSIVSFH-- 725
            |::|.||.:.||||||||:|:||:||:..|....|.:|...:::| |.|   .|....:..|:
 Worm   385 KIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQKKARLARIRIVKNASGLALFNKK 449

  Fly   726 --HINLKDAFAKSMDLIDVIVDTGKQTNVVHPKGKRQSTPNIGRQTLDVQSAPGHNLSQTDGNST 788
              |.....||.:.....|.:.|.                        |:.....|:|.|....:|
 Worm   450 RAHEARMLAFEQGHLSFDALRDE------------------------DIFEIQHHHLLQCLEKAT 490

  Fly   789 EGEST-------SGRN---PATTGTGCYKNYDHVANLRNSNLHNRR----GSSSEQDAVPPYSFD 839
            |.|..       .|||   |:.|           |:|:......||    ...:|:
 Worm   491 EREFVESEVMFEGGRNTPPPSET-----------ASLKGKTKRKRRLCCVSKENEE--------- 535

  Fly   840 NPNARQTSMMAMESYRREQQALLQQQQQQ 868
                       ||...||.:....|...|
 Worm   536 -----------MEELDRETRVTFNQNMDQ 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB	309..416	CDD:197585	39/106 (37%)
		BTB_2	309..408	CDD:280393	36/98 (37%)
		Ion_trans	501..700	CDD:278921	88/198 (44%)
		Ion_trans_2	613..696	CDD:285168	43/82 (52%)
shl-1	NP_500975.2	BTB_POZ	6..149	CDD:365784	45/137 (33%)
		Ion_trans	187..416	CDD:366146	98/238 (41%)
		DUF3399	460..528	CDD:371777	18/102 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810