Protein Alignment Shab and KCNG3

DIOPT Version :9

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_579875.1
• Gene: KCNG3 / 170850
• HGNCID: 18306
• Length: 436
• Species: Homo sapiens
• Alignment Length: 423
• Identity: 159/423 - (37%)
• Similarity: 249/423 - (58%)
• Gaps: 29/423 - (6%)

  Fly   309 VSINVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILN 373
            |.:||||.|:.:....|:..|..|:.||..|.:...::|:||||....||||||||.::|..||.
Human    11 VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAFGFILL 75

  Fly   374 FYR-TGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKEAESLRQRDEE 437
            :.| .|||.....||.|:|.:::.|||::..:||.|||.:...|..:.:.....:...:..|||.
Human    76 YVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSADEPGVLGRDEA 140

  Fly   438 EFGEGKCAEYQKYLWEL---LEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQLQH--IDNGT 497
            ..|..:.|..:::|..:   .|:|.:|.||:::|.:|::|:::|.:.|..:|||..::  .||.:
Human   141 RPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCASTLPDWRNAAADNRS 205

  Fly   498 PQDNPQLA---------MVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVS-L 552
            ..|..:.:         ::||:||.|||.|.|:||..|.:|.:|.|..|||||||||.||::| |
Human   206 LDDRSRYSAGPGREPSGIIEAICIGWFTAECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVL 270

  Fly   553 FLLETNKNATDQFQDVRRVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMG 617
            ..:.|.:|:  |.|.....::|.|:|||..::|||||..|||:||.||:..|:|:.:|::|:.:.
Human   271 MTVFTGENS--QLQRAGVTLRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVA 333

  Fly   618 VLIFSSLAYFAEK----DEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGV 678
            :.|||:|:...|.    :..:..|.|||...||..|:||||||||:||.|..|:::|.||.:.|:
Human   334 MAIFSALSQLLEHGLDLETSNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGI 398

  Fly   679 LVIALPIPIIVNNFAEFYKNQMRREKALKRREA 711
            :::||||..|.::|.:.|..       ||.|.|
Human   399 VLLALPITFIYHSFVQCYHE-------LKFRSA 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB	309..416	CDD:197585	44/107 (41%)
		BTB_2	309..408	CDD:280393	41/99 (41%)
		Ion_trans	501..700	CDD:278921	88/212 (42%)
		Ion_trans_2	613..696	CDD:285168	35/86 (41%)
KCNG3	NP_579875.1	BTB_POZ_KCNG3	11..122	CDD:349729	45/110 (41%)
		Ion_trans	219..420	CDD:395416	88/209 (42%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	373..378		4/4 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11537
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.920