Protein Alignment Shab and LOC1277771

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: XP_061512001.1
• Gene: LOC1277771 / 1277771
• VectorBaseID: AGAMI1_002465
• Length: 622
• Species: Anopheles gambiae
• Alignment Length: 701
• Identity: 218/701 - (31%)
• Similarity: 325/701 - (46%)
• Gaps: 178/701 - (25%)

  Fly   307 SRVSINVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSI 371
            :||.:||||:|||....||:::|.|||.||.|...         :|....|||||||||..|:.:
Mosquito     8 NRVVLNVGGIRHETYKATLKKIPATRLSRLTEALA---------NYDPILNEYFFDRHPGVFAQV 63

  Fly   372 LNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCC-----QHKYHQRKENVHEEMRKEAESL 431
            ||:|||||||...::|...|.::||:||:|...:|.||     ||:..|....|.|.:..:.|..
Mosquito    64 LNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLERLDLDTEKP 128

  Fly   432 RQRD-------EEEFGEGKCAEYQ---KYLWELLEKPNTSFAARVIAVISILFIVLSTIALTLNT 486
            .:.:       |:::.:|..:.:|   ..:|.|.::|.:|.||::|.|||:.||.:|.::..|.|
Mosquito   129 TEEELARKFGYEDDYLKGTVSWWQHMKPQMWSLFDEPYSSNAAKIIGVISVFFICVSILSFCLKT 193

  Fly   487 -----LPQLQHID----NGT-------PQDNPQLAM--VEAVCITWFTLEYILRFSASPDKWKFF 533
                 :|.:::|.    ||:       .|.|..:|.  :|.||..|||.|.::||.:||:|.:|.
Mosquito   194 HPDMRVPVIRNITVKTANGSTAWVLDKTQTNAHVAFFYIECVCNAWFTFEILVRFISSPNKCEFV 258

  Fly   534 KGGLNIIDLLAILPYFVSLFL------LETNKNATDQFQDVRRVVQVFRIMRILRILKLARHSTG 592
            ...:||||.:|.|.::|.|.|      ||   ||.        :::.|.|:||:|:.||.|||:|
Mosquito   259 TSSVNIIDYIATLSFYVDLVLQRFASHLE---NAD--------ILEFFSIIRIMRLFKLTRHSSG 312

  Fly   593 LQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFAEKDEKD--TKFVSIPETFWWAGITMTTVG 655
            |:.|..|.|.|.|||.||:.||.:|::||:||.|:||:.:.:  ..|.|||...|||.:||||||
Mosquito   313 LKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQANPHNDFNSIPLGLWWALVTMTTVG 377

  Fly   656 YGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNFAEFYKNQMRREKALKRREAL-------- 712
            |||:.|.|.:|..:|.:|.:.|||.||||:|:||:|||.:|.:...|.|..|:|..:
Mosquito   378 YGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQ 442

  Fly   713 DRAKREGSIVSF-------HHINLKDAFAKSMDLIDVIVDTGKQTNVVHPKGKRQSTPNIGRQTL 770
            .|...:|..:..       ..:|.    .|:.||...|...|.....:.||       |:|..|
Mosquito   443 PRTAGQGGGIGMPGSGPMARRMNQ----VKTKDLGPKIGPIGASIVAMCPK-------NVGLHT- 495

  Fly   771 DVQSAPGHNLSQTDGNSTEGESTSGRNPATTGTGCYKNYDHVANLRNSNLHNRRGSSSEQDAVPP 835
                                      |||            :|..:                 |.
Mosquito   496 --------------------------NPA------------LAMCK-----------------PT 505

  Fly   836 YSFDNPNARQTSMMAMESYRREQQALLQQQQQQQQQMLQMQQIQQKAPNGNGGATGGGVANNLAM 900
            :....|:...|.||           |:.:....:..:        ..|..|.| |||
Mosquito   506 FEVRPPSIVPTPMM-----------LVPRDSTYKPTV--------TTPTANSG-TGG-------- 542

  Fly   901 VAASSAATAVATATNASNASNTA---PGSEGAEGGGDGDGGGVDDDNLSQA 948
                ...||:|.||:.:|.|.|.   ..|:.:....:|.||....::.||:
Mosquito   543 ----LTITALANATSTNNNSTTTVNNNNSKNSANSNNGTGGKTIANSNSQS 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	50/111 (45%)
		Ion_trans	464..700	CDD:459842	109/261 (42%)
LOC1277771	XP_061512001.1	None