Protein Alignment Shab and LOC1277769

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: XP_061513689.1
• Gene: LOC1277769 / 1277769
• VectorBaseID: AGAMI1_010466
• Length: 661
• Species: Anopheles gambiae
• Alignment Length: 735
• Identity: 204/735 - (27%)
• Similarity: 310/735 - (42%)
• Gaps: 228/735 - (31%)

  Fly   307 SRVSINVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSI 371
            :|:.:||||:|:|....||:::|.|||.||.|...         :|....|||||||||..|:.:
Mosquito     5 NRIILNVGGIRYETYKATLKKIPATRLSRLTEALA---------NYDPVLNEYFFDRHPGVFAQV 60

  Fly   372 LNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKEAESL----- 431
            ||:|||||||...::|...|.::||:||:|...:|.||...|     :||.:.:.....|
Mosquito    61 LNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTY-----SVHRDTQSTLAILDKLEL 120

  Fly   432 --RQRDEEEF------------GEGKCAEYQK-YLWELLEKPNTSFAARVIAVISILFIVLSTIA 481
              .|..||..            ||..|.:..| .:|.|.::|::|..|:::|.||:.||.:|.|:
Mosquito   121 DDEQPSEEAIARLFGFEEALLNGELTCWQRTKPKIWALFDEPSSSTGAKIVAGISVFFICISVIS 185

  Fly   482 LTLNTLPQLQ-------------------------------H-------IDNGTP---------- 498
            ..|.|.|.|:                               |       :|.|.|
Mosquito   186 FCLKTHPGLRVEIPAILNITTNGSASVLPDGLPTTLDELLDHGRLDELLLDYGAPTGTGTGSTST 250

  Fly   499 -----------------------------------------------------QDNPQLAMVEAV 510
                                                                 |.:.....||.|
Mosquito   251 TTTTTSATTESHSASPTRPETTTQRTGRIVSSAYRMNSGKGASIVENWQETYGQPHEAFFYVELV 315

  Fly   511 CITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLFLLETNKNATDQFQ---DVRRVV 572
            |..||.:|..:|...:|:.::|.|..:|||||.|.|.::            ||..|   :...::
Mosquito   316 CNVWFIIELTVRLVVAPNIFEFIKSPVNIIDLAATLSFY------------TDVCQRMGEQTGLL 368

  Fly   573 QVFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFAEK--DEKDT 635
            :.|.|:||||:.||.|||.||:.|..|.:.|.:||.||:.||.:|:::|:||.|:|||  |..|.
Mosquito   369 EAFSIVRILRLFKLTRHSPGLRILIHTFKASARELTLLVFFLVLGIVVFASLVYYAEKLQDNPDN 433

  Fly   636 KFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNFAEFYKNQM 700
            :|.|||...|||.:|||||||||:.|.|.:|..:|.:|.:.|||.||||:|:||:||:.||.:..
Mosquito   434 QFKSIPLGLWWAIVTMTTVGYGDMAPKTYVGMFVGALCALAGVLTIALPVPVIVSNFSMFYSHTQ 498

  Fly   701 RREKALKRREAL-----DRAKREGSIVS-------------FHHINLKDAFAKSMDLIDVIVDTG 747
            .|.|..|:|..:     .|.||:..:.:             .|....||||..:
Mosquito   499 ARSKLPKKRRRVLPVEQPRRKRDMGVANRRVNALKHQHTQPTHPAIFKDAFGGA----------- 552

  Fly   748 KQTNVVHPKGKRQSTPNIGRQTLDVQSAPGHNLSQTDGNSTEGESTSGRNPATTGTGCYKNYDHV 812
               .:.|..|     .|:...||...|.||..:.              :.||....|.:.|...:
Mosquito   553 ---KIGHVNG-----VNVIGLTLQGPSVPGLAVL--------------KPPAVLQQGDFINVPQL 595

  Fly   813 ANLRNSNLHNRRGSSSEQDAVPPYSFDNPNARQTSMMAMESYRREQQALLQQQQQQQQQMLQMQQ 877
                 |:|..|:.::...|.:.|.        |..::.        ...:::::.:.::|:.::.
Mosquito   596 -----SSLQPRQPTTGNVDLLLPL--------QPKLLV--------PLAVERRESRPEEMIPLEP 639

  Fly   878 IQQKAPNGNGGATGGGVANN 897
            ......:.||||:|    ||
Mosquito   640 KVTLQSDPNGGASG----NN 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	46/106 (43%)
		Ion_trans	464..700	CDD:459842	105/341 (31%)
LOC1277769	XP_061513689.1	None