Protein Alignment Shab and LOC1270812

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: XP_061513643.1
• Gene: LOC1270812 / 1270812
• VectorBaseID: AGAMI1_001190
• Length: 1080
• Species: Anopheles gambiae
• Alignment Length: 1130
• Identity: 230/1130 - (20%)
• Similarity: 336/1130 - (29%)
• Gaps: 503/1130 - (44%)

  Fly    19 STPLQTNNGVLQMVGQLQGGQAAGQQQQQQQATQQQQHSKQQQQQQQQQQQQLQLKQHQQQQQDI 83
            :|.:..|.|..:.:.:    |:...:.|||:|...|.|.:|||||||.||.|||..||||.||
Mosquito     9 TTTITMNRGEQENLYR----QSRNLRLQQQEAKAHQLHQQQQQQQQQHQQHQLQQLQHQQHQQ-- 67

  Fly    84 LYQQHNE---------------AIAIARG----------LQAATPADIGD------NQPYYDTSG 117
            |.::|..               .|.||||          |:...||...|      ..|..:|:.
Mosquito    68 LGKRHYSYGNIHQFSGATVALPPIMIARGLGSFAMDDQQLRQTGPAHCDDLVLSVLKSPVKETTN 132

  Fly   118 NVDWERA--------------MGAGGAG----------AYGGIGIGSLPAAGGA--AYHLGPANP 156
            .:...|:              ||.||.|          |.|.:..|  |..||.  :|.....:.
Mosquito   133 LLTGSRSALSASPSAGSNGITMGGGGGGSTQTQTPSPCATGSVSPG--PGGGGGMISYRALQGSE 195

  Fly   157 AGLV--------SRHLDYGDGG----HLAGPSA---------------GLPAGA----------- 183
            ..||        :..|:.||..    |..||..               |.||.|
Mosquito   196 DDLVDDVESAMETTELNAGDPHRAPLHPGGPCTSSSPRALKFLRRFRPGKPARAFEPHHKRVPTP 260

  Fly   184 -------------------VGSGAG---------------------AGAGAGASVTGSGSGAGTG 208
                               ||:..|                     .|...|....|:|.|.|
Mosquito   261 MRRKNRSRSRSRSNDLLDGVGASQGNIVVDDDDDDDVDMDDDVNELPGVAMGLHHHGAGGGGG-- 323

  Fly   209 TGTGAGSGSGSGAAGKEVRYAPFPVASPTHSIPTTSQQIVGSVGGVGVGGASSQSISGGVPTHSQ 273
               |.|.||||..||                            ||..:          |||.
Mosquito   324 ---GGGDGSGSATAG----------------------------GGKNL----------GVPN--- 344

  Fly   274 SNTTGALQRTHSRSMSSIPPPEPFMIAQSKAVNSRVSINVGGVRHEVLWRTLERLPHTRLGRLRE 338
                               |..|..:...:|..::...                  |.|.|:
Mosquito   345 -------------------PYYPIALPIDQAFKAKYVF------------------HHRRGK--- 369

  Fly   339 CTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDEL 403
                          ::.:..|.|..||..:                 :|.:
Mosquito   370 --------------TVQERFYVFLEHPGGW-----------------LCFV-------------- 389

  Fly   404 YLESCCQHKYHQRKENVHEEMRKEAESLRQRDEEEFGEGKCAEYQKYLWELLEKPNTSFAARVIA 468
                     ||                                               |:..::.
Mosquito   390 ---------YH-----------------------------------------------FSVFLLV 398

  Fly   469 VISILFIVLSTIALTLNTLPQLQHIDNGTPQDNPQLAMVEAVCITWFTLEYILRF--SASPDKWK 531
            ::.::|.||||             ||..:...|..|..:|...:.:|.:||::|.  :....|:.
Mosquito   399 LVCLIFSVLST-------------IDEYSKFANETLFWMEICLVVFFGVEYLVRLWSAGCRSKYM 450

  Fly   532 FFKGGLN-------IIDLLAILPYFVSLFLLETNKNATDQFQDVRRVVQVF--------RIMRIL 581
            .|.|.|.       ||||:.::   .|:.:|....|.           |||        |.::||
Mosquito   451 GFCGRLRFIRKPICIIDLIVVV---ASMVVLSVGSNG-----------QVFATSAIRGIRFLQIL 501

  Fly   582 RILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSS-LAYFAEKD----EKDTKFVSIP 641
            |:|.:.|.....:.||..:....:|| :..|::....||||| ..|.||||    :....|.|..
Mosquito   502 RMLHVDRQGGTWRLLGSVVFIHRQEL-ITTLYIGFLGLIFSSYFVYLAEKDVLGPDGKADFASYA 565

  Fly   642 ETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNFAEFYKNQMRREKAL 706
            :..||..||:||:||||..|.|.:||::.:...:..:...|||..|:.:.|| ....|.:|:|..
Mosquito   566 DALWWGVITVTTIGYGDTVPQTWMGKIVASCFSVFAISFFALPAGILGSGFA-LKVQQKQRQKHF 629

  Fly   707 KRR--------------EALDRAKREGSIVSFHHINLKDAFAKSMDLIDVIVDTGKQTNVVHPKG 757
            .|:              .|.|:        |||.......:.||.|
Mosquito   630 NRQIPAAAMLIQCLWRCYAADK--------SFHSDATWQIYVKSAD------------------- 667

  Fly   758 KRQSTPNIGRQTLDVQSAPGHNLSQTDGNSTEGESTSGRNPATTGTGCYKNYDHVANLRNSNLHN 822
                                      :||:....||:                         |.:
Mosquito   668 --------------------------NGNNNGNSSTA-------------------------LPS 681

  Fly   823 RRGSSSEQDAVPPYSFDNPNARQTSMMAMESYRREQQALLQQQQQQQQQMLQMQQIQQKAPNGNG 887
            :.|..|              |..:..:.::..||....|.:::.:.:.:..||:......| |.|
Mosquito   682 QLGKVS--------------AMFSGTLMVQVARRGASVLKRRKSRNRMEAPQMKPPLSAGP-GGG 731

  Fly   888 GATGGGVANNLAMVAASSAATAVATATNASNASNTAPGSEGAEGGGDGDGGGVDDDN-----LSQ 947
            .:.||..|...|..||..     ..|:..|.||...||..|..|||.|.|||....:     |:|
Mosquito   732 PSVGGATATQTAAAAAGG-----PNASGVSCASAAGPGGPGGSGGGGGGGGGGASGSQGPTALAQ 791

  Fly   948 A-----KGLPIQMMITPGEVAELRR 967
            .     .|.|:....|||..|:|.:
Mosquito   792 TAAGSMDGGPLGTPNTPGGAADLAK 816

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	8/107 (7%)
		Ion_trans	464..700	CDD:459842	71/257 (28%)
LOC1270812	XP_061513643.1	None