Protein Alignment Shab and Kcnc3

DIOPT Version :9

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_446449.2
• Gene: Kcnc3 / 117101
• RGDID: 621358
• Length: 769
• Species: Rattus norvegicus
• Alignment Length: 601
• Identity: 204/601 - (33%)
• Similarity: 287/601 - (47%)
• Gaps: 134/601 - (22%)

  Fly   217 SGSGAAGKEVRYA-PFPVASPTHS-----IPTTSQQI---------VGSVGGVGVGGASSQSISG 266
            |.||..|...::: |.|...|..|     :|...||.         .|:....|.||..::..|
  Rat     9 SFSGRQGTRKQHSQPAPTPQPPESSPPPLLPPPQQQCAQPGTAASPAGAPLSCGPGGRRAEPCS- 72

  Fly   267 GVPTHSQSNTTGALQRTHSRSMSSIPPPEPFMIAQSKAVNSRVSINVGGVRHEVLWRTLERLPHT 331
            |:|..:.....|                       ....:.::.|||||||||....||..||.|
  Rat    73 GLPAVAMGRHGG-----------------------GGGDSGKIVINVGGVRHETYRSTLRTLPGT 114

  Fly   332 RLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLE 396
            ||..|   |..||....  ||....:|:||||||..|:.:||:|||||||...::|...|.::|.
  Rat   115 RLAGL---TEPEAAARF--DYDPGTDEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELG 174

  Fly   397 YWGVDELYLESCCQHKYHQRKENVHEEMRKEAESLRQRD-----------------EEEFGEG-- 442
            :||:||..:|:||...|.|     |.:..:..:|....|                 ::|.|.|
  Rat   175 FWGIDETDVEACCWMTYRQ-----HRDAEEALDSFEAPDSSGNANANAGGAHDAGLDDEAGAGGG 234

  Fly   443 -----------KCAE-----------------------YQKYLWELLEKPNTSFAARVIAVISIL 473
                       .|.:                       :|..:|.|.|.|.:|.|||.:|..|:.
  Rat   235 GLDGAGGELKRLCFQDAGGGAGGPAGGPGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLF 299

  Fly   474 FIVLSTIALTLNTLPQLQHIDN----------GTPQDN---------PQLAMVEAVCITWFTLEY 519
            ||::|.....|.|.....||.|          |.|.:|         |.|..||.||:.|||.|:
  Rat   300 FILISITTFCLETHEGFIHISNKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEF 364

  Fly   520 ILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLFLLETNKNATDQFQDVRRVVQVFRIMRILRIL 584
            ::|.:..|||.:|.|..|||||.:||||:::.:.|...:..|.   :||...::|.|.:|||||.
  Rat   365 LMRVTFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAA---KDVLGFLRVVRFVRILRIF 426

  Fly   585 KLARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFAEK---DEKD------TKFVSI 640
            ||.||..||:.||.|||.|..|..||::|||:|||||:::.|:||:   |..|      |.|.:|
  Rat   427 KLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNI 491

  Fly   641 PETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNFAEFYKNQMRREKA 705
            |..||||.:||||:||||:||.|..|.::|.:|.:.|||.||:|:|:|||||..:|...|.::|.
  Rat   492 PIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKL 556

  Fly   706 LKRR-EALDRAKREGS 720
            .|:: :.:.|..:.||
  Rat   557 PKKKNKHIPRPPQPGS 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB	309..416	CDD:197585	50/106 (47%)
		BTB_2	309..408	CDD:280393	47/98 (48%)
		Ion_trans	501..700	CDD:278921	100/216 (46%)
		Ion_trans_2	613..696	CDD:285168	47/91 (52%)
Kcnc3	NP_446449.2	BTB	92..194	CDD:197585	51/111 (46%)
		BTB_2	92..186	CDD:280393	47/98 (48%)
		Ion_trans	344..551	CDD:278921	99/209 (47%)
		Ion_trans_2	460..541	CDD:285168	39/80 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920