Protein Alignment Shab and Kcns1

DIOPT Version :9

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_446406.1
• Gene: Kcns1 / 117023
• RGDID: 621524
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 540
• Identity: 189/540 - (35%)
• Similarity: 294/540 - (54%)
• Gaps: 86/540 - (15%)

  Fly   298 MIAQSKAVNSRV---------SINVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIVELCDDYS 353
            |:::.....|||         .:||||||..:..|.|.|.|.||||||:...:.|....|||||.
  Rat     1 MVSEFPGPGSRVPWRPRDEALRVNVGGVRRLLSARALARFPGTRLGRLQAAVSEEQARRLCDDYD 65

  Fly   354 LADNEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKE 418
            .|..|::|||||..|..:|:|||||.||::||:||.||..:.:|||:.|..|.:||:.:|.:|:.
  Rat    66 AAAREFYFDRHPGFFLGLLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALATCCRARYLERRV 130

  Fly   419 NVHEEMRKEAE------------SLRQRDEEEFGEGKCAEYQKYLWELLEKPNTSFAARVIAVIS 471
            .......::::            |..||:...:|..:|...::.||..:|.|..|..:::.:.:|
  Rat   131 TRPRAWDEDSDAPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFSCVS 195

  Fly   472 ILFIVLSTIALTLNTLPQLQHIDNGTP-------------QDNPQLAMVEAVCITWFTLEYILRF 523
            |..::.|..|:.:::||:.|..:....             :|:|.|..:|..||.||:.|...|.
  Rat   196 IGVVLASIAAMCIHSLPEYQAREAAAAVAAVAAGRSAEDVRDDPVLRRLEYFCIAWFSFEVSSRL 260

  Fly   524 SASPDKWKFFKGGLNIIDLLAILPYFVSLF---LLETNKNAT-DQFQDVRRVVQVFRIMRILRIL 584
            ..:|....||...||:||::::||::::|.   .|...:.|: ::..|:.:||||||:|||.|:|
  Rat   261 LLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGAALGDRRGASGEELGDLGKVVQVFRLMRIFRVL 325

  Fly   585 KLARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFAEKDEKDTKFVSIPETFWWAGI 649
            |||||||||:|||.||::||:|:|:|:|:||:||.:||.:||.||  ||:..|.:||..:||..:
  Rat   326 KLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYTAE--EKNVGFDTIPACWWWGTV 388

  Fly   650 TMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNFAEFYKNQMRREKALKRREALDR 714
            :||||||||:.|.|..||:..:.|.:.|:||:||||.||.|.|:.||    ||:|||
  Rat   389 SMTTVGYGDVVPETVAGKLAASGCILGGILVVALPITIIFNKFSHFY----RRQKAL-------- 441

  Fly   715 AKREGSIVSFHHINLKDAFAKSMDLIDVIVDTGKQTNVVHPKGKRQSTPNIGRQTLDVQSAPGHN 779
               |.::.|......:|..:....:.||.::|.::|:
  Rat   442 ---EAAVRSSGQREFEDLLSSVDGVSDVSLETSRETS---------------------------- 475

  Fly   780 LSQTDGNSTEGESTSGRNPA 799
               .:|.||:.|:.:...||
  Rat   476 ---QEGRSTDLETQAPSEPA 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB	309..416	CDD:197585	53/115 (46%)
		BTB_2	309..408	CDD:280393	50/107 (47%)
		Ion_trans	501..700	CDD:278921	96/202 (48%)
		Ion_trans_2	613..696	CDD:285168	41/82 (50%)
Kcns1	NP_446406.1	BTB_2	21..120	CDD:280393	49/98 (50%)
		BTB	23..125	CDD:197585	51/101 (50%)
		Ion_trans	238..439	CDD:278921	98/206 (48%)
		Ion_trans_2	355..433	CDD:285168	41/79 (52%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	392..397		4/4 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	464..497		10/60 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11537
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920