Protein Alignment Shab and kcnv2

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: XP_002934230.1
• Gene: kcnv2 / 100498412
• XenbaseID: XB-GENE-940169
• Length: 562
• Species: Xenopus tropicalis
• Alignment Length: 489
• Identity: 176/489 - (35%)
• Similarity: 274/489 - (56%)
• Gaps: 60/489 - (12%)

  Fly   311 INVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFY 375
            |||||..:.:.:......|.:|:|||...|..:..::||||||..::.|||||.|..|..|.|||
 Frog   112 INVGGTSYRISYGVAASYPKSRIGRLATYTDRQRKLDLCDDYSPKEDVYFFDRDPAIFHHIYNFY 176

  Fly   376 RTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKE----AESLRQRDE 436
            |||.|.:.||:|..:|.:::.||||...:...||:..:.:|:::::|:::.:    ||...:.:|
 Frog   177 RTGVLWVRDELCPRSFLEEINYWGVRVKHTPRCCRISFEERQDDLNEQLKVQRELRAEMETEENE 241

  Fly   437 EEFGEGKCAEYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQLQHID-NGTPQD 500
            |.|........::.:|.::|||.:|..|:.|||.|..|:::|.:|:||||:..:|:.: .|.|..
 Frog   242 ELFRGMLYGHLRRRIWNMMEKPFSSVTAKAIAVASSFFVLISVVAMTLNTVEDMQYKNAAGLPSG 306

  Fly   501 NPQLAMVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLFLLE-------TN 558
            .|.|..||.:|||:|||||:||..::||...|.:..||.:||:||||.::.: |||       :.
 Frog   307 KPYLEHVETLCITFFTLEYLLRLMSTPDLQHFGRSVLNAVDLIAILPLYLQM-LLESFADEDRSG 370

  Fly   559 KNATDQFQ--------DVRRVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFLA 615
            |.::.:.:        .:.:|:::.|:|||.||||||||||||::.|||||..|:::|.|.||:|
 Frog   371 KGSSHEHEIEAVGRVGKLGQVLRIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLFLFIA 435

  Fly   616 MGVLIFSSLAYFAEKDEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLV 680
            |||..||::.|..|.|...|.|.|||..:|||.::::||||||:||.|.||::...:|...|:::
 Frog   436 MGVFSFSAMVYSVEHDVSGTNFTSIPHAWWWAAVSISTVGYGDVYPETHLGRLFAFLCIAFGIIL 500

  Fly   681 IALPIPIIVNNFAEFYKNQMRREKALKRREALDRAKREGSIVSFHHINLKDAFAKSMDLIDVIVD 745
            ..:||.|:.|.|:::|..       ||..|.....|:.|.:    |.
 Frog   501 NGMPISILYNKFSDYYSK-------LKSYEYTTIRKKRGKV----HF------------------ 536

  Fly   746 TGKQTNVVHPKGKRQSTPNIGRQTLDVQSAPGHN 779
            ||:....|:........||          .||||
 Frog   537 TGRAVQKVNSCCCGPPVPN----------TPGHN 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	42/102 (41%)
		Ion_trans	464..700	CDD:459842	107/251 (43%)
kcnv2	XP_002934230.1	BTB_POZ_KCNV2	110..217	CDD:349732	42/104 (40%)
		Ion_trans	269..520	CDD:459842	107/258 (41%)