Protein Alignment Shab and kcng4

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: XP_002934997.1
• Gene: kcng4 / 100497160
• XenbaseID: XB-GENE-985941
• Length: 506
• Species: Xenopus tropicalis
• Alignment Length: 431
• Identity: 170/431 - (39%)
• Similarity: 268/431 - (62%)
• Gaps: 18/431 - (4%)

  Fly   309 VSINVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILN 373
            :.|||||:::.:.|.||:..|.||||:||.|:::|.|:::|||:....||:||||:|.:||.|::
 Frog    62 IIINVGGIKYLMPWSTLDEFPMTRLGKLRFCSSYEEIIQICDDFDEDTNEFFFDRNPCAFSMIVS 126

  Fly   374 FYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKEAESLRQRD--- 435
            |...|||.::.|||.|:|.|:|.|||::|..||.||..|..|:.|.: .|:|||.|:.|.|:
 Frog   127 FLAAGKLRLLREMCALSFQDELTYWGIEESKLERCCLRKLFQKLEEL-AEIRKEEEAQRNRETIC 190

  Fly   436 --EEEFGEGKCAEYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQLQ-HIDNG- 496
              |:....|.|   ...|.:::|.|.:....:|.|.:||:|:..:.|.|.::|:|.|: ..|.|
 Frog   191 VLEDNTKVGHC---MGKLRDMVENPQSGIPGKVFACLSIIFVATTAINLCVSTMPDLRAEEDRGE 252

  Fly   497 TPQDNPQLAMVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLFLLETNK-- 559
            ..|....:.::|.:|:.||:||:.|||..:..|.:||||.|||||:||||||:|||.:.:..|
 Frog   253 CSQMCYNIFIIETICVAWFSLEFFLRFIQAKSKCQFFKGPLNIIDVLAILPYYVSLIVEDEQKTV 317

  Fly   560 ---NATDQFQDVRRVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIF 621
               ::....:.:..|::|.|.:|||.:::|||||.|||:||.|:|...:|.|||:|||.:.|.:|
 Frog   318 DKPSSNSYLEKIGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLCVAVTLF 382

  Fly   622 SSLAYFAEKD-EKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPI 685
            :.|.:.||.: .:..:|.|:|.::|||.|:||||||||:.|.:..|:|:.....:.|:|::|.|.
 Frog   383 APLVHLAENEMGRCQEFTSVPASYWWAIISMTTVGYGDMVPRSIPGQVVALSSILSGILIMAFPA 447

  Fly   686 PIIVNNFAEFYKNQMRREKALKRR-EALDRAKREGSIVSFH 725
            ..|.:.|:..|....|.::.|:.| ..|..|.:.|...:|:
 Frog   448 TSIFHTFSRCYSELKREQERLQSRLMRLKDANQSGESDTFN 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	51/104 (49%)
		Ion_trans	464..700	CDD:459842	97/243 (40%)
kcng4	XP_002934997.1	BTB_POZ_KCNG4	59..170	CDD:349730	52/107 (49%)
		Ion_trans	219..462	CDD:459842	97/242 (40%)