Protein Alignment Shab and kcna2

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: XP_031752644.1
• Gene: kcna2 / 100496794
• XenbaseID: XB-GENE-991578
• Length: 499
• Species: Xenopus tropicalis
• Alignment Length: 525
• Identity: 184/525 - (35%)
• Similarity: 274/525 - (52%)
• Gaps: 101/525 - (19%)

  Fly   263 SISGGVPTHSQSNTTGALQRTHSRSMSSIPPPEPFMIAQSKAVNSRVSINVGGVRHEVLWRTLER 327
            :::.|.||...|...|..|.::.        |||     ......||.||:.|:|.|...:||.:
 Frog     2 TVATGDPTDETSALPGHPQDSYD--------PEP-----DHECCERVVINISGLRFETQLKTLSQ 53

  Fly   328 LPHTRLG----RLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRT-GKLHIVDEMC 387
            .|.|.||    |:|.             :....|||||||:..||.:||.:|:: |:|.....:.
 Frog    54 FPETLLGDPKKRMRY-------------FDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVP 105

  Fly   388 VLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKEAESLRQRDEEEFGEGKCAEYQKYLW 452
            :..||:::.::.:.|..:                 |:.:|.|...:.:|....:.   ||||.:|
 Frog   106 LDIFSEEIRFYELGEEAM-----------------EIFREDEGFIKEEERPLPDN---EYQKQVW 150

  Fly   453 ELLEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQLQHID--------NGTPQDNPQLA---- 505
            .|.|.|.:|..||:||:||::.|::|.::..|.|||..:..:        |..|..|..:.
 Frog   151 LLFEYPESSGPARIIAIISVMVILISIVSFCLETLPVFRDENEDMHGSGVNYYPYSNSTVRYQKS 215

  Fly   506 --------MVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSL--FLLETNKN 560
                    :||.:||.||:.|:::||.|.|.|..||...:||||::||:|||::|  .|.|..::
 Frog   216 NTFTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKTED 280

  Fly   561 ATDQFQDVR-RVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSSL 624
            .....|.:. .:::|.|::|:.||.||:|||.|||.||.||:.|.:|||||:.||.:||::|||.
 Frog   281 GQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSA 345

  Fly   625 AYFAEKDEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIV 689
            .||||.||:|::|.|||:.||||.::||||||||:.|||..||::|::|.|.|||.||||:|:||
 Frog   346 VYFAEADERDSQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIV 410

  Fly   690 NNFAEFYKNQMRREKAL------------------KRREALDRAK------REG---SIVSFHHI 727
            :||..||..:...|:..                  |.|.|...:|      :||   |...|...
 Frog   411 SNFNYFYHRETEGEEQAQYLQVTSCPKIPSSPDLQKSRSASTLSKSDYMEIQEGVNHSNEDFREK 475

  Fly   728 NLKDA 732
            |||.|
 Frog   476 NLKTA 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	32/112 (29%)
		Ion_trans	464..700	CDD:459842	117/258 (45%)
kcna2	XP_031752644.1	BTB_POZ	33..159	CDD:453885	44/158 (28%)
		Ion_trans	162..420	CDD:459842	117/257 (46%)