DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shab and kcna1

DIOPT Version :9

Sequence 1:	NP_001189037.1	Gene:	Shab / 38352	FlyBaseID:	FBgn0262593	Length:	1607	Species:	Drosophila melanogaster
Sequence 2:	XP_004912857.1	Gene:	kcna1 / 100492822	XenbaseID:	XB-GENE-991584	Length:	489	Species:	Xenopus tropicalis

Alignment Length:	484	Identity:	171/484 - (35%)
Similarity:	266/484 - (54%)	Gaps:	78/484 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   308 RVSINVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSIL 372
            ||.|||.|:|.|...:||.:.|:|.||..::...:         :....|||||||:..||.:||
Frog    35 RVVINVAGLRFETQLKTLSQFPNTLLGNPKKRMRY---------FDPLRNEYFFDRNRPSFDAIL 90

  Fly   373 NFYRT-GKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKEAESLRQRDE 436
            .:|:: |:|.....:.:..||::::::.:.|..:|     |:.:.:..:.||.|...|.
Frog    91 YYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAME-----KFREDEGFIREEERPLPEK------ 144

  Fly   437 EEFGEGKCAEYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQL-------QHID 494
                     |:|:.:|.|.|.|.:|..||:||::|::.|::|.:...|.|||:|       :.::
Frog   145 ---------EFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVIFCLETLPELKDERIFSRRVN 200

  Fly   495 NGTP--QDN---PQLAMVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLFL 554
            |.|.  :.|   ....:||.:||.||:.|.::||.|.|.|.:|||..:|.||::||:|||::|..
Frog   201 NSTVFYKSNIFTDPFFVVETLCIIWFSFELVVRFFACPSKPEFFKNIMNFIDIVAIIPYFITLGT 265

  Fly   555 LETNKNATDQFQDVR--RVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMG 617
            ....:....:.:...  .:::|.|::|:.||.||:|||.|||.||.||:.|.:|||||:.||.:|
Frog   266 EMAEQEGPQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIG 330

  Fly   618 VLIFSSLAYFAEKDEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIA 682
            |::|||..||||.:|.::.|.|||:.||||.::||||||||:||.|..||::|::|.|.|||.||
Frog   331 VILFSSAVYFAEAEEDESHFASIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIA 395

  Fly   683 LPIPIIVNNFAEFYKNQMRREKA----------------LKRREALDRAKRE---------GSIV 722
            ||:|:||:||..||..:...|:.                |.||.:...:|.|         .||.
Frog   396 LPVPVIVSNFNYFYHRETEGEEQAQLLHVSTPNLASDSDLSRRSSSTMSKSEYMEIEEDLNNSID 460

  Fly   723 SFHHINLK---------DAFAKSMDLIDV 742
            :|...|::         :...||..|.||
Frog   461 NFREANIRTGNCTIANQNCVNKSKLLTDV 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB	309..416	CDD:197585	32/107 (30%)
		BTB_2	309..408	CDD:280393	31/99 (31%)
		Ion_trans	501..700	CDD:278921	98/203 (48%)
		Ion_trans_2	613..696	CDD:285168	48/82 (59%)
kcna1	XP_004912857.1	BTB_POZ	34..160	CDD:365784	43/153 (28%)
kcna1	XP_004912857.1	Ion_trans	163..412	CDD:366146	112/248 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910