Protein Alignment Shab and kcna1

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: XP_004912857.1
• Gene: kcna1 / 100492822
• XenbaseID: XB-GENE-991584
• Length: 489
• Species: Xenopus tropicalis
• Alignment Length: 484
• Identity: 171/484 - (35%)
• Similarity: 266/484 - (54%)
• Gaps: 78/484 - (16%)

  Fly   308 RVSINVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSIL 372
            ||.|||.|:|.|...:||.:.|:|.||..::...:         :....|||||||:..||.:||
 Frog    35 RVVINVAGLRFETQLKTLSQFPNTLLGNPKKRMRY---------FDPLRNEYFFDRNRPSFDAIL 90

  Fly   373 NFYRT-GKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKEAESLRQRDE 436
            .:|:: |:|.....:.:..||::::::.:.|..:|     |:.:.:..:.||.|...|.
 Frog    91 YYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAME-----KFREDEGFIREEERPLPEK------ 144

  Fly   437 EEFGEGKCAEYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQL-------QHID 494
                     |:|:.:|.|.|.|.:|..||:||::|::.|::|.:...|.|||:|       :.::
 Frog   145 ---------EFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVIFCLETLPELKDERIFSRRVN 200

  Fly   495 NGTP--QDN---PQLAMVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLFL 554
            |.|.  :.|   ....:||.:||.||:.|.::||.|.|.|.:|||..:|.||::||:|||::|..
 Frog   201 NSTVFYKSNIFTDPFFVVETLCIIWFSFELVVRFFACPSKPEFFKNIMNFIDIVAIIPYFITLGT 265

  Fly   555 LETNKNATDQFQDVR--RVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMG 617
            ....:....:.:...  .:::|.|::|:.||.||:|||.|||.||.||:.|.:|||||:.||.:|
 Frog   266 EMAEQEGPQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIG 330

  Fly   618 VLIFSSLAYFAEKDEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIA 682
            |::|||..||||.:|.::.|.|||:.||||.::||||||||:||.|..||::|::|.|.|||.||
 Frog   331 VILFSSAVYFAEAEEDESHFASIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIA 395

  Fly   683 LPIPIIVNNFAEFYKNQMRREKA----------------LKRREALDRAKRE---------GSIV 722
            ||:|:||:||..||..:...|:.                |.||.:...:|.|         .||.
 Frog   396 LPVPVIVSNFNYFYHRETEGEEQAQLLHVSTPNLASDSDLSRRSSSTMSKSEYMEIEEDLNNSID 460

  Fly   723 SFHHINLK---------DAFAKSMDLIDV 742
            :|...|::         :...||..|.||
 Frog   461 NFREANIRTGNCTIANQNCVNKSKLLTDV 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	33/106 (31%)
		Ion_trans	464..700	CDD:459842	112/249 (45%)
kcna1	XP_004912857.1	BTB_POZ	34..160	CDD:453885	43/153 (28%)
		Ion_trans	163..412	CDD:459842	112/248 (45%)