Protein Alignment Shab and kcnb1

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: XP_031750650.1
• Gene: kcnb1 / 100489405
• XenbaseID: XB-GENE-982937
• Length: 875
• Species: Xenopus tropicalis
• Alignment Length: 587
• Identity: 350/587 - (59%)
• Similarity: 444/587 - (75%)
• Gaps: 53/587 - (9%)

  Fly   278 GALQRTHSRSMSSIPPPEPFMIAQSKAVNSRVSINVGGVRHEVLWRTLERLPHTRLGRLRECTTH 342
            |.:.:..|||.:|: ||:|..|.:|||.:.||.:||||:.||||||||:|||.||||:||:|.||
 Frog     3 GWMNKHGSRSTTSL-PPDPMDIIRSKACSRRVKLNVGGLAHEVLWRTLDRLPRTRLGKLRDCNTH 66

  Fly   343 EAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLES 407
            |.::|:||||:|.:|||||||||.:|:||||||||||||:::|||.|:||.:|:|||:||:||||
 Frog    67 ECLMEICDDYNLEENEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFSQELDYWGIDEIYLES 131

  Fly   408 CCQHKYHQRKENVHEEMRKEAESLRQRDEEEFGEGKCAEYQKYLWELLEKPNTSFAARVIAVISI 472
            |||.:|||:||.::||:::|||:||:|:.|||....||:.:|.||:||||||:|.||:::|:|||
 Frog   132 CCQARYHQKKEQMNEELKREAETLREREGEEFDNTCCADKRKKLWDLLEKPNSSVAAKILAIISI 196

  Fly   473 LFIVLSTIALTLNTLPQLQHIDN-GTPQDNPQLAMVEAVCITWFTLEYILRFSASPDKWKFFKGG 536
            ||||||||||:|||||.||.||. |...||||||.||||||.|||:||:|||.:||:|||||||.
 Frog   197 LFIVLSTIALSLNTLPDLQGIDEFGQTTDNPQLAHVEAVCIAWFTMEYLLRFLSSPNKWKFFKGP 261

  Fly   537 LNIIDLLAILPYFVSLFLLETNKNATDQFQDVRRVVQVFRIMRILRILKLARHSTGLQSLGFTLR 601
            ||:|||||||||:|::||.|:||:.. |||:||||||:|||||||||||||||||||||||||||
 Frog   262 LNVIDLLAILPYYVTIFLTESNKSVL-QFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLR 325

  Fly   602 NSYKELGLLMLFLAMGVLIFSSLAYFAEKDEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALG 666
            .||.|||||:||||||::|||||.:||||||:||||.|||.:||||.|||||||||||||.|.||
 Frog   326 RSYNELGLLILFLAMGIMIFSSLVFFAEKDEEDTKFKSIPASFWWATITMTTVGYGDIYPKTLLG 390

  Fly   667 KVIGTVCCICGVLVIALPIPIIVNNFAEFYKNQMRREKALKRREALDRAKREGSIVSFHHINLKD 731
            |::|.:|||.||||||||||||||||:||||.|.|:|||:||||||:||||.|||||   :|:||
 Frog   391 KIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALERAKRNGSIVS---MNMKD 452

  Fly   732 AFAKSMDLIDVIVD-----TGK----QTNVVHPK-------------------GKRQSTPNIGRQ 768
            |||:|::|:||:|:     :|:    |.|.:.|.                   .|.|.:|...|
 Frog   453 AFARSVELMDVVVEKTDDNSGRKDKVQDNHLSPSRWKWTKRTLSETSSNKSFDAKEQGSPEKAR- 516

  Fly   769 TLDVQSAPGH-NLSQTDGNSTEGESTSGRNPATTGTGCYKNYDHVANLRNSNLHNRRGSSSEQDA 832
               ..|:|.| |:.|.:....:...|..:              .|.|.::||..::.....|.:|
 Frog   517 ---CSSSPQHLNVQQLEDIYNKMAKTQSQ--------------PVLNSKDSNQPSKPAEELEMEA 564

  Fly   833 VP 834
            :|
 Frog   565 IP 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	74/107 (69%)
		Ion_trans	464..700	CDD:459842	183/236 (78%)
kcnb1	XP_031750650.1	BTB_POZ_KCNB2	15..141	CDD:349719	85/126 (67%)
		Ion_trans	188..424	CDD:459842	183/236 (78%)
		Kv2channel	467..720	CDD:397541	21/118 (18%)