Protein Alignment Shab and kcnc2

DIOPT Version :9

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: XP_002939991.2
• Gene: kcnc2 / 100489216
• XenbaseID: XB-GENE-1013657
• Length: 598
• Species: Xenopus tropicalis
• Alignment Length: 613
• Identity: 212/613 - (34%)
• Similarity: 309/613 - (50%)
• Gaps: 98/613 - (15%)

  Fly   306 NSRVSINVGGVRHEVLWRTLERLPHTRLGRLR-ECTTHEAIVE--LCDDYSLAD--NEYFFDRHP 365
            |.|:.:||||.|||....||:.:|.|||..|. |..:.:.:.:  :...:::..  ||:||||||
 Frog     7 NERIILNVGGTRHETYRSTLKTVPGTRLALLACESQSEQGLDQQTVSGSFNITSRGNEFFFDRHP 71

  Fly   366 KSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVHEEMRKEAES 430
            ..|:.:||:|||||||...::|...|.::|.:||:||..:|.||...|.|     |.:..:..:.
 Frog    72 GVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQ-----HRDAEEALDI 131

  Fly   431 LRQRD------------EEEFGE--------------GKCAEYQKYLWELLEKPNTSFAARVIAV 469
            ....|            ||:.|:              |:....|..:|.|.|.|.:|.|||.||.
 Frog   132 FETPDLITGEPPPIDEYEEDLGKRLAIEDVVCPDGKVGRWRRLQPRMWALFEDPYSSRAARFIAF 196

  Fly   470 ISILFIVLSTIALTLNT-------LPQLQHIDNGTP-------QDNPQLAMVEAVCITWFTLEYI 520
            .|:.||::|.....|.|       :.:.:.::|||.       :.:|.|..||.||:.|||.|::
 Frog   197 ASLFFILVSITTFCLETHEAFNTIINKTETVNNGTELISLIEIETDPALTYVEGVCVVWFTFEFL 261

  Fly   521 LRFSASPDKWKFFKGGLNIIDLLAILPYFVSLFLLETNKNATDQFQDVRRVVQVFRIMRILRILK 585
            :|....|||.:|.:..|||||.:||||:::.:.|...:..|.   :||...::|.|.:|||||.|
 Frog   262 VRVIFCPDKLEFIRNLLNIIDFVAILPFYLEVGLSGLSSKAA---KDVLGFLRVVRFVRILRIFK 323

  Fly   586 LARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFAEK---------DEKDTKFVSIP 641
            |.||..||:.||.|||.|..|..||::|||:|||||:::.|:||:         ..|.|:|.:||
 Frog   324 LTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPSDPSASKHTQFKNIP 388

  Fly   642 ETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNFAEFYKNQMRREK-A 705
            ..||||.:||||:||||:||.|..|.::|.:|.:.|||.||:|:|:|||||..:|...|.::| .
 Frog   389 IGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLP 453

  Fly   706 LKRREALDRAKREGSIVSFHHINLKDAFAKSMDL----IDVIVDT--GKQTNVV-HPKGKRQSTP 763
            .||::.:..|.:.||          ..|.| |||    ....|||  ||...:: |......|:.
 Frog   454 RKRKKYIPHAPQTGS----------PTFCK-MDLNMGCNSTQVDTCLGKDNRLMEHNMSGEDSSG 507

  Fly   764 NIGRQTLDVQSAPGHNL-----SQTDGNSTEGES---TSGRNPATTGTGCYKNYDHVANLRNSNL 820
            :      |...:||...     |..|.|...|..   |:|.....|..|..|.|:...:|  :|:
 Frog   508 S------DQPLSPGERYPIRRSSTRDKNRRTGTCFLLTTGEYTCNTDGGIRKGYEKSRSL--NNI 564

  Fly   821 HNRRGSSSEQDAV-PPYSFDNPNARQTS 847
            ....|::.....| .|||...|..|..|
 Frog   565 AGLAGNALRLSPVTSPYSSPCPLRRSRS 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB	309..416	CDD:197585	44/111 (40%)
		BTB_2	309..408	CDD:280393	41/103 (40%)
		Ion_trans	501..700	CDD:278921	97/207 (47%)
		Ion_trans_2	613..696	CDD:285168	46/91 (51%)
kcnc2	XP_002939991.2	BTB_KCNC2_4	7..129	CDD:349722	48/126 (38%)
		Ion_trans	191..447	CDD:395416	110/258 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010