Protein Alignment Shab and kcnd1

DIOPT Version :9

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: XP_031747765.1
• Gene: kcnd1 / 100488387
• XenbaseID: XB-GENE-6047565
• Length: 631
• Species: Xenopus tropicalis
• Alignment Length: 578
• Identity: 181/578 - (31%)
• Similarity: 285/578 - (49%)
• Gaps: 85/578 - (14%)

  Fly   292 PPPEPFMIAQSKAVNSRVSINVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIVELCDDYSLAD 356
            |.|:|....:.|: :..:.:||.|.:.:....||:|.|.|.||...:           |.:...|
 Frog    26 PMPKPPSDKRMKS-DEILVVNVSGRKFQTWKNTLDRYPDTLLGSTEK-----------DFFFNQD 78

  Fly   357 -NEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENV 420
             .||||||.|:.|..|||||||||||.....|:.||.::|.::|:....:..||..:|..||:..
 Frog    79 TQEYFFDRDPEMFRHILNFYRTGKLHYPRHECIQAFDEELSFYGIIPEIIGDCCLEEYRDRKKEN 143

  Fly   421 HEEMRKEAESLRQRDEEEFGEGKC---AEYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIAL 482
            .|.:.::.|:      |..|:...   :.:::.||...|.|:||..|.|...::..||.:|.||.
 Frog   144 LERLAEDTEA------ETAGDTPLPPDSTFRQRLWRAFENPHTSTMALVFYYVTGFFIAVSVIAN 202

  Fly   483 TLNTLP------QLQHIDNGTPQDNPQLAMV--EAVCITWFTLEYILRFSASPDKWKFFKGGLNI 539
            .:.|:|      :|:.:..|   :...||.|  :..|:..||.||::|..|:|.:.||.:..::|
 Frog   203 VVETVPCRPPAGRLKELPCG---EKYNLAFVCMDTACVLIFTFEYLMRLFAAPSRCKFMRSVMSI 264

  Fly   540 IDLLAILPYFVSLFLLETNKNATDQFQDVRRVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSY 604
            ||::||:|:::.|.:.| |:|.:..|       ...|:.|:.||.|.:|||.||:.||:||::..
 Frog   265 IDVVAIMPFYIGLVMPE-NENVSGAF-------VTLRVFRVFRIFKFSRHSQGLRILGYTLKSCA 321

  Fly   605 KELGLLMLFLAMGVLIFSSLAYFAEKDEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVI 669
            .|||.|:..|.|.::||:::.::|||....|||.|||..||:..:||||:||||:.|.|..||:.
 Frog   322 SELGFLLFSLTMAIIIFATVMFYAEKGTSKTKFTSIPAAFWYTIVTMTTLGYGDMVPDTIAGKIF 386

  Fly   670 GTVCCICGVLVIALPIPIIVNNFAEFYKNQMRREKALKRRE---------------ALDRAKREG 719
            |::|.:.||||||||:|:||:||:..|....|.:|...:::               |..|.|..|
 Frog   387 GSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQKIRLARIRLAKSNTTGAFLRYKESG 451

  Fly   720 SI---VSFHHINLKDAFAKSMDLIDVIVDTGKQT----NVVHPKGKRQSTPNIGRQTLDVQSAPG 777
            .:   ...|.:.:|:..|..:....::....|.|    ...|...:...|.:||.:|
 Frog   452 GLEEGTESHALCVKNRSAFELQHHHLLHCLEKTTCHEFTDQHTYSEALMTESIGYRT-------- 508

  Fly   778 HNLSQTDGNSTEGESTSGRNPATTGTGC--YKNYDHVANLRNSNLHNRRGSSSEQDAV 833
                        ..|||..:....||.|  .:|......|.||.:...|||..|.:.:
 Frog   509 ------------SRSTSVSSQQGFGTSCCPRRNKRRAIRLANSTVSVSRGSMQELETL 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB	309..416	CDD:197585	39/107 (36%)
		BTB_2	309..408	CDD:280393	36/99 (36%)
		Ion_trans	501..700	CDD:278921	85/200 (43%)
		Ion_trans_2	613..696	CDD:285168	42/82 (51%)
kcnd1	XP_031747765.1	BTB_POZ_KCND1	6..143	CDD:349724	45/128 (35%)
		Ion_trans	184..415	CDD:395416	96/241 (40%)
		DUF3399	445..542	CDD:403174	23/116 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000