Protein Alignment Shab and kcnv1

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: XP_002939028.1
• Gene: kcnv1 / 100487006
• XenbaseID: XB-GENE-956997
• Length: 503
• Species: Xenopus tropicalis
• Alignment Length: 494
• Identity: 198/494 - (40%)
• Similarity: 305/494 - (61%)
• Gaps: 35/494 - (7%)

  Fly   252 GGVGVGGASSQSISGGVPTHSQSNTTGALQRTHSRSMSSIPPPEPFMIAQSKAVNSRVSINVGGV 316
            ||:||.....:| :|.||..|:...:.:.....|....|...|.|         ...::|||||.
 Frog    14 GGLGVATQCGES-AGKVPASSRDGDSDSALSLDSSVFCSDYFPAP---------KDHLTINVGGS 68

  Fly   317 RHEVLWRTLERLPHTRLGRLRECTTHEAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRTGKLH 381
            |..:..:.|...|.||||||......| :.|||||.:|.||||||||..:.|..|:|||:||.||
 Frog    69 RFILSHKVLSNHPETRLGRLVSSGGQE-VYELCDDANLMDNEYFFDRSSQMFKYIMNFYKTGHLH 132

  Fly   382 IVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRK---ENVHEEMRKEAESLRQRDEEEFGEGK 443
            :::|:|.::|..:::|||:|||.::.||:.:|:::|   |::  :::|:.|.: :.:||:|....
 Frog   133 VMEELCAVSFLQEIQYWGIDELNIDLCCRERYYRKKLMSESL--DIKKDEEEI-EAEEEDFSGVV 194

  Fly   444 CAEYQKYLWELLEKPNTSFAARVIAVISILFIVLS-----TIALTLNTLPQLQHIDNGTPQDNPQ 503
            ...:::.||::||||.:|.||:....:|:.|||:|     .|:..:|::            |.|.
 Frog   195 FEHFRQTLWDILEKPGSSVAAKTFGTLSMTFIVISIANMVLISSEMNSI------------DPPL 247

  Fly   504 LAMVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLFLLETNKNATDQFQDV 568
            |..:|.:||||||||..|||.....|.:|.:..:||||::||||::::| ::|.....:.:.::|
 Frog   248 LNALEYICITWFTLELALRFLCVKHKCRFLRSVVNIIDIVAILPFYITL-IVENLYGESTELENV 311

  Fly   569 RRVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFAEKDEK 633
            .|:||..|::|.||:|||.||||||:|||.|:...|:|:|||:|||::|:.|||:|.|..|.:..
 Frog   312 GRIVQSLRLLRSLRMLKLGRHSTGLKSLGMTIAQCYEEVGLLLLFLSVGISIFSALEYAVEHNIP 376

  Fly   634 DTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNFAEFYKN 698
            ||.|.|:|..:|||..:|||||||||.|.|..||::..:|.:.|:||:||||.||.:.||..|..
 Frog   377 DTTFTSVPNAWWWATTSMTTVGYGDIRPDTTFGKIVAFLCILSGILVLALPIAIINDRFAACYFT 441

  Fly   699 QMRREKALKRREALDRAKREGSIVSFHHINLKDAFAKSM 737
            ...:|.||::||||.:..:..|..|..::||:|.:|||:
 Frog   442 LKIKEAALRQREALKKLMKNISAESDTNVNLRDIYAKSV 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	49/107 (46%)
		Ion_trans	464..700	CDD:459842	105/240 (44%)
kcnv1	XP_002939028.1	BTB_POZ_KCNV1	61..169	CDD:349731	50/108 (46%)
		Ion_trans	215..439	CDD:459842	104/236 (44%)