Protein Alignment Shab and kcnf1b

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: XP_005157014.1
• Gene: kcnf1b / 100334378
• ZFINID: ZDB-GENE-090312-39
• Length: 484
• Species: Danio rerio
• Alignment Length: 463
• Identity: 189/463 - (40%)
• Similarity: 270/463 - (58%)
• Gaps: 47/463 - (10%)

  Fly   280 LQRT---HSRSMSSIPPPEPFMIAQSKAVNSRVSINVGGVRHEVLWRTLERLPHTRLGRLRECTT 341
            |.||   |..|.||....|             :::|:||||..:....|.|.|.:||..|..|.|
Zfish     4 LPRTRFAHCNSSSSSDEKE-------------IAVNIGGVRLVLCGDILNRYPDSRLAELVNCPT 55

  Fly   342 H--EAIVELCDDYSLADNEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELY 404
            .  :.|..|||||.....|::|||.|.||..|:..|..|::|:...:|.:.|..::|:|.:|..|
Zfish    56 RSFDVISSLCDDYDPGKREFYFDRDPDSFKCIVEVYYFGEVHMKRGICPICFIKEMEFWKIDLSY 120

  Fly   405 LESCCQHKYHQRKENVHEEMRK--------EAESLRQRDEEEFGEGKCAEYQKYLWELLEKPNTS 461
            |:.||:....:::|.:.|...|        |.:....|.|         .:||::|:|:|||.:|
Zfish   121 LDECCKSNLTEKEEELAEIADKVKLILDDLECDPAVSRTE---------RWQKFVWKLMEKPESS 176

  Fly   462 FAARVIAVISILFIVLSTIALTLNTLPQLQHIDN-GTPQDNPQLAMVEAVCITWFTLEYILRFSA 525
            ..||||||:|.|||::|::.:.|.|||.||..|: |...::|.|..:|..||.|||:||:||.::
Zfish   177 LPARVIAVVSFLFILISSVVMCLGTLPDLQVEDSEGNRVEHPSLDAIETACIGWFTVEYVLRLAS 241

  Fly   526 SPDKWKFFKGGLNIIDLLAILPYFVSLFL--LETNKNATDQFQDVRRVVQVFRIMRILRILKLAR 588
            ||:|.:|....:|:||.||:||::|.|.|  |.|   |..:..:|::.||..|||||.||.||||
Zfish   242 SPNKLRFALSFMNMIDFLAVLPFYVVLVLTCLGT---AMMELVNVQQAVQALRIMRIARIFKLAR 303

  Fly   589 HSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFAEKDEKDTKFVSIPETFWWAGITMTT 653
            ||:|||:|.:.|:.|:||||||::::.:|:.:||:|.|..|:...:|.|.|||::||||.|||||
Zfish   304 HSSGLQTLTYALKRSFKELGLLLMYMGVGIFVFSALGYTMEQSHPETLFRSIPQSFWWAIITMTT 368

  Fly   654 VGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNFAEFYKNQMRREKALKRR------EAL 712
            ||||||||.|.||:....:..:|||:.|||||..|:|||..:|..|...|.|.|..      .||
Zfish   369 VGYGDIYPKTTLGRCNAAISFLCGVIAIALPIHPIINNFVIYYNKQKVLETAAKHELELMELRAL 433

  Fly   713 DRAKREGS 720
            :...|..|
Zfish   434 ELTVRSAS 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	39/109 (36%)
		Ion_trans	464..700	CDD:459842	120/238 (50%)
kcnf1b	XP_005157014.1	BTB_POZ_Kv5_KCNF1	22..136	CDD:349690	41/126 (33%)
		Ion_trans	179..415	CDD:459842	120/238 (50%)