Protein Alignment Shab and kcng1

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_001096675.1
• Gene: kcng1 / 100125206
• XenbaseID: XB-GENE-1011042
• Length: 508
• Species: Xenopus tropicalis
• Alignment Length: 476
• Identity: 167/476 - (35%)
• Similarity: 277/476 - (58%)
• Gaps: 31/476 - (6%)

  Fly   292 PPPEPFMIAQSKAVNSRVSINVGGVRHEVLWRTLERLPHTRLGRLRECTTHEAIVELCDDYSLAD 356
            |..:.|..|..........|||||.|:.:.|.|||..|.||||:|:.|:..:.|:.:||||.:..
 Frog    47 PTEDLFKSAHPDDRKHHAIINVGGFRYLLPWTTLEEFPLTRLGQLKLCSNFDEILSICDDYDVTC 111

  Fly   357 NEYFFDRHPKSFSSILNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKE--- 418
            ||:||||:|.:|.:||.|.:.|||.::.|||.|:|.::|.|||::|..||.||:.:|.|:.|
 Frog   112 NEFFFDRNPGAFRTILTFLQVGKLRLLREMCALSFQEELLYWGIEEDNLEWCCKRRYIQKMEEFA 176

  Fly   419 --NVHEEMRKEAESLRQRDEEEFGEGKCAEYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIA 481
              |:.||...|.|:..:.::    |.|.....::|.:::|||.:....::.|.:|:||:.::.:.
 Frog   177 ELNLREEELIENENASEPED----ESKLDICMRHLGDMVEKPQSGLPGKIFACLSVLFVTITAVN 237

  Fly   482 LTLNTLPQLQHIDNGTPQDNP--QLAMVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLA 544
            |:::|:|.|:..:........  .:.:||:||:.||:||::|||..:|.|:.|.:..||:||::|
 Frog   238 LSISTMPDLREEEEKGVCSKMCYNIFIVESVCVGWFSLEFLLRFIQAPSKFAFIRRPLNLIDIVA 302

  Fly   545 ILPYFVSLFLLETNK------NATDQFQDVRRVVQVFRIMRILRILKLARHSTGLQSLGFTLRNS 603
            ||||:::|.:..|:.      :.......|..|:::.|.:|||.:::|||||.|||:||.|.|..
 Frog   303 ILPYYITLVVDNTSDGQKKPGSGNSYLDKVGLVLRILRALRILYVMRLARHSLGLQTLGLTARRC 367

  Fly   604 YKELGLLMLFLAMGVLIFSSLAYFAEKDEKDT-KFVSIPETFWWAGITMTTVGYGDIYPTTALGK 667
            .:|.|||:|||.:.:.:|:.|.|..|.:..|: :|.|||..:|||.||||||||||:.|.:..|:
 Frog   368 TREFGLLLLFLCVAIALFAPLLYLIENEMADSQEFTSIPACYWWAVITMTTVGYGDMVPRSIPGQ 432

  Fly   668 VIGTVCCICGVLVIALPIPIIVNNFAEFYKNQMRREKALKRREA--LDRAKREGSIVSFHHINLK 730
            |:.....:.|:|::|.|:..|.:.|:..|....:.::.|..|:|  |.:.|.:.|.:|
 Frog   433 VVALSSILSGILLMAFPVTSIFHTFSRSYIELKQEQERLMCRKAQLLMKTKSQMSSIS------- 490

  Fly   731 DAFAKSMDLIDVIVDTGKQTN 751
                :..|::.....:|.:.|
 Frog   491 ----QGSDMLSESASSGAKAN 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	50/107 (47%)
		Ion_trans	464..700	CDD:459842	90/244 (37%)
kcng1	NP_001096675.1	BTB_POZ_KCNG1_2	59..172	CDD:349728	52/112 (46%)
		Ion_trans	221..461	CDD:459842	89/239 (37%)