Protein Alignment Shab and kcnf1

DIOPT Version :10

• Sequence 1: NP_001189037.1
• Gene: Shab / 38352
• FlyBaseID: FBgn0262593
• Length: 1607
• Species: Drosophila melanogaster
• Sequence 2: NP_001096396.1
• Gene: kcnf1 / 100124998
• XenbaseID: XB-GENE-979363
• Length: 484
• Species: Xenopus tropicalis
• Alignment Length: 404
• Identity: 180/404 - (44%)
• Similarity: 263/404 - (65%)
• Gaps: 9/404 - (2%)

  Fly   309 VSINVGGVRHEVLWRTLERLPHTRLGRLRECTT--HEAIVELCDDYSLADNEYFFDRHPKSFSSI 371
            :::||||:|..:....|.|.|.|||..|..|..  ::||..|||||.....|::|||.|.:|..|
 Frog    23 ITVNVGGIRQVLYGDVLNRYPETRLAELVNCMAGGYDAIFSLCDDYDPGKKEFYFDRDPDAFKCI 87

  Fly   372 LNFYRTGKLHIVDEMCVLAFSDDLEYWGVDELYLESCCQHKYHQRKENVH-EEMRKEAESLRQRD 435
            :..|..|::|:...:|.:.|.:::::|.||...|:.||  |.|..::|:. ||:.|..:::....
 Frog    88 IEVYLYGEVHMKKGICPICFKNEMDFWRVDLDLLDDCC--KSHLNEKNLELEEIAKRVQTILDDL 150

  Fly   436 EEEFGEGKCAEYQKYLWELLEKPNTSFAARVIAVISILFIVLSTIALTLNTLPQLQHID-NGTPQ 499
            ..:..|.|...:||.||:.:|||.:||.||:.|::|.|||::|:..:.:.|:|::|..| .|...
 Frog   151 GGDTSESKWKRFQKCLWKFMEKPESSFPARITAILSFLFILISSTVMCIGTIPEMQVEDLQGNHV 215

  Fly   500 DNPQLAMVEAVCITWFTLEYILRFSASPDKWKFFKGGLNIIDLLAILPYFVSLFLLETNKNATDQ 564
            ::|.|..:|.|||.||||||:||..:||::..|....:||||:|||||::||:.|  ||..||..
 Frog   216 EHPTLDSIETVCIGWFTLEYLLRLISSPNRLHFALSFMNIIDVLAILPFYVSIIL--TNLGATIM 278

  Fly   565 -FQDVRRVVQVFRIMRILRILKLARHSTGLQSLGFTLRNSYKELGLLMLFLAMGVLIFSSLAYFA 628
             ..:|::.:|..|||||.||.||||||:|||:|.:.|::|:||||||:::||:|:.:||:|.|..
 Frog   279 GLTNVQQAIQALRIMRIARIFKLARHSSGLQTLTYALKSSFKELGLLLMYLAVGIFVFSALGYTM 343

  Fly   629 EKDEKDTKFVSIPETFWWAGITMTTVGYGDIYPTTALGKVIGTVCCICGVLVIALPIPIIVNNFA 693
            |:...||.|.|||::||||.|||||||||||||.|.|||:......:|||:.|||||..|:|||.
 Frog   344 EQSHPDTLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAATSFLCGVIAIALPIHPIINNFV 408

  Fly   694 EFYKNQMRREKALK 707
            ::|..|...|.|.|
 Frog   409 KYYNKQRVLETATK 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shab	NP_001189037.1	BTB_POZ_Shab-like	306..414	CDD:349720	39/106 (37%)
		Ion_trans	464..700	CDD:459842	121/237 (51%)
kcnf1	NP_001096396.1	BTB_POZ_Kv5_KCNF1	21..136	CDD:349690	41/114 (36%)
		Ion_trans	179..415	CDD:459842	121/237 (51%)