DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9970 and CG30357

DIOPT Version :9

Sequence 1:	NP_647754.1	Gene:	CG9970 / 38351	FlyBaseID:	FBgn0035380	Length:	484	Species:	Drosophila melanogaster
Sequence 2:	NP_724707.1	Gene:	CG30357 / 246563	FlyBaseID:	FBgn0050357	Length:	451	Species:	Drosophila melanogaster

Alignment Length:	460	Identity:	112/460 - (24%)
Similarity:	186/460 - (40%)	Gaps:	71/460 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SSTKTLVREGESIPQDNNKSISSTIEEDLLQQNKSEKEKTKGTSTDKSTTTDGDLPTVKMDKILQ 77
            ||.|.::|   ......||.:.:..|.:.:|:...|.......:|..:.::..:|      ||..
  Fly    21 SSNKVILR---GYASKANKDVEAVEELEEIQEMNDELRDLFINTTAINCSSLSEL------KIQT 76

  Fly    78 QQRAELLWKTFTDEEYSDWKTFKDSNYKVPLLSVFSYVKSKPFIAEIPNLPPKISGPQLMTNILK 142
            .....|..:|.....||.....|               |||  |:::  |..|::..|.:.:::|
  Fly    77 DAFNTLKERTLFSLGYSTAGLLK---------------KSK--ISKV--LKGKVNLYQQIVSLVK 122

  Fly   143 SNYGALALVQIGENKFKCIPCLLRCFSVWFGIRDW-RITRFKFKEREVPSGGFKVVYEWM--RTN 204
            ......:.:.||:........:|:.||..|  ||. ........|:.:....|.::||||  .|.
  Fly   123 QRTKTNSEITIGKTSHPVHLMVLQSFSRMF--RDMGNDLSVALPEKMITPRSFGLIYEWMIEDTP 185

  Fly   205 KLPEFDELVPALQVACHLKVTLLEKEIWQILSDESVREKVAFLVYLGARRMPALGALCEAMLFRL 269
            .||... |:.....|..:::..|.::....| |....|..|.::|..|:.: .|..:....|.|:
  Fly   186 VLPRLG-LLEVFHAAKFMEIPQLVRQCKYCL-DHGFTEDSAAMLYFEAKIL-KLEVIHLQYLERV 247

  Fly   270 RKYFLALVGSPHFVRLKVDVLEMLLRQDSIGVNSEMEVFFAVIRWLGHSRGRKRREHFQRLMKCV 334
            .|:||.||.|..|:||.:..:.:|::.|.||||:|:|||.|..|||.| ...:|.|:...::..:
  Fly   248 SKFFLTLVASKEFLRLPLKSMLLLIQSDLIGVNTELEVFMAAARWLSH-HWPQREENVTDVVSSI 311

  Fly   335 RFHHMPMTFLFSLRESFNHPEKFDLFSKEPGMLAFNTDPEMMELLEHAIYFISVRT-QCDDINEF 398
            ||..:|...|..|       :|.|:.|...|.:.  ..|.:.:.:...|.:.:.|. ...|...|
  Fly   312 RFGLIPPWLLIRL-------QKPDVTSVGVGRIV--AQPIVRQAIHEGIAYTTTRMFYGKDREAF 367

  Fly   399 LSTCESHHIEVVLPRWWVYHVNCPFHLR-----TIDFPY------------QHRFTATDFGDYID 446
            ........::..:.|.|:|...||:|.|     |:|..|            |||       ||..
  Fly   368 KHYLHKACVKPPVQRTWIYDRKCPYHHRMQCRNTVDLTYDAFLEYLNYTQRQHR-------DYWK 425

  Fly   447 SIQKV 451
            |::.|
  Fly   426 SLEPV 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9970	NP_647754.1	BACK	254..346	CDD:197943	33/91 (36%)
CG9970	NP_647754.1	DUF4734	373..450	CDD:292506	21/94 (22%)
CG30357	NP_724707.1	BTB	131..217	CDD:197585	21/89 (24%)
		BTB	<139..211	CDD:295341	18/74 (24%)
		BACK	226..323	CDD:285009	35/98 (36%)
		DUF4734	337..427	CDD:292506	20/98 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469522
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H119992
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006713
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22667
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.940