|
Fly 648 KKKRKRCGECVGCQRKDNCGECAPCRNDKSHQICKQRRCEKLTEK----KEPKAKTIVFGADGQP 708
:|||||||.|..|:|.:|||.|..|.|.::|||||.|:||.|.:| ||
Mouse 51 RKKRKRCGTCDPCRRLENCGSCTSCTNRRTHQICKLRKCEVLKKKAGLLKE-------------- 101
Fly 709 VRPDSKRGRG---KGKSSGSGNGTVNATGIAAG--NGTPTTGSRARKNSTKANKLNAAAASATSP 768
|..:::.|.| :|.:..:|:......|...| :..|.....:|:.||....:|.|...|...
Mouse 102 VEINAREGTGPWAQGATVKTGSELSPVDGPVPGQMDSGPVYHGDSRQLSTSGAPVNGAREPAGPG 166
Fly 769 RLSPVPAATLLPQQSPNTTSATGNLQQQQQQQQQQ---YQQHQQLLSQQQLLSQQQQQY------ 824
.|. .|......|.|:..:|:|.....:.:.... :....:.:|....||.:..:.
Mouse 167 LLG--AAGPWRVDQKPDWEAASGPTHAARLEDAHDLVAFSAVAEAVSSYGALSTRLYETFNREMS 229
Fly 825 -------QQPQQQQQHFQQQQQQHLQQQHAQQQH-------------LPQQQHQITAQIQTMKDQ 869
:.|:.:......:....||...|..:| .|.....:..:|::|..:
Mouse 230 REAGSNGRGPRPESCSEGSEDLDTLQTALALARHGMKPPNCTCDGPECPDFLEWLEGKIKSMAME 294
Fly 870 PQQ--PMAPMAFYPTWQADPSQGWQNQFI-QQIPQNTPAITSLNSLDFQTQSYAYPSNGYVQSGL 931
..| |..|.|..|:....|:...:...: .::|| .|.:..| .|.....|.|...|..:|:.:
Mouse 295 GGQGRPRLPGALPPSEAGLPAPSTRPPLLSSEVPQ-VPPLEGL-PLSQSALSIAKEKNISLQTAI 357
Fly 932 GFD-----------PNYGRSPYAAPVQRYDFQSQQLS-TAPSAINQVGLQSVAGFAPSYAGQVSA 984
..: |::..|..:.|: .:.|| :||....|..|: |||:
Mouse 358 AIEALTQLSSALPQPSHSTSQASCPL------PEALSPSAPFRSPQSYLR-----APSW------ 405
Fly 985 APVPPSQQQQQQQQQQQQQHLGADLNKTMSGNDTPGYPRVSSVPPRSLNCNGYSGDYSGSPATNS 1049
||.|.::... ...|:|.:|..: ||......:..| ..|||..
Mouse 406 -PVVPPEEHPS------------------FAPDSPAFPPAT---PRPEFSEAWGTD--TPPATPR 446
Fly 1050 NS----NNNSSSNTSNTNNSNASNNNATTVVSGGTTTPAPPPTVVAQPASSPMQPPNQAVPQSPT 1110
|| ..:............::::...:|.......|..|...|..|:|||...|: |.|..
Mouse 447 NSWPVPRPSPDPMAELEQLLGSASDYIQSVFKRPEALPTKPKVKVEAPSSSPAPVPS---PISQR 508
Fly 1111 RSNMLQQQQQQHQSPTGNGLQPYVAPQQQQQQQQQQHLSSPPMQD-----WNWQQQQQQQQSLGG 1170
.:.:|..:...||. ....||.::..::....:|.|..|.|...: | |..
Mouse 509 EAPLLSSEPDTHQK-AQTALQQHLHHKRNLFLEQAQDASFPTSTEPQAPGW-WAP---------- 561
Fly 1171 EGYAQGERLHLNTRIKSMIMRKSDPKDPPPDLQQQPQQVQQQQQTGHFLSYSHHLRPEAALSANG 1235
...|...||| :.|::.:::..| .|.|
Mouse 562 ---------------------PGSPAPRPPD--KPPKEKKKKPPT----------------PAGG 587
Fly 1236 PSSATPTHPLPNLQQQQQQVQQVQQVQQQQQQQQAVG-GQVAAEPIGGGGDHIWKPHHANSFKKP 1299
|..|..| .|.::...::..|:::.:.:..|...:. .|:..|.: ||
Mouse 588 PVGAEKT--TPGIKTSVRKPIQIKKSRSRDMQPLFLPVRQIVLEGL-----------------KP 633
Fly 1300 SVVSGYPASQDAQLQLQLQQHQPGQHTTINHSVDPPVVPPQQHPPVAAAQPKKSRSRSKASRAAA 1364
....| .|.|..|| ||.|| ||:.||
Mouse 634 QASEG-----QAPLPAQL-------------SVPPP-----------------------ASQGAA 657
Fly 1365 AAAAAAEAAAEIDRDRNSTDPGGGGLKPLSAHYPPHPHAAGGPPPGQDYH--SQYIKTEPGLLG- 1426
:.:.|.....| |..|.:.|.|......||.|:.. |..:..:.|..|
Mouse 658 SQSCATPLTPE----------------PSLALFAPSPSGDSLLPPTQEMRSPSPMVALQSGSTGG 706
Fly 1427 --PPQPNKMEGYERNYQNFIQYADFCQNDGQGQPVQQHHGHGQQDYAGYHHNSAYYGAGASSFQQ 1489
||..:|:|...|.:: |:|..:.|
Mouse 707 PLPPADDKLEELIRQFE-----AEFGDSFG----------------------------------- 731
Fly 1490 NFQQNFVPGYQHSTYGARGKPPANQPHQIHGHGQSLMELDRKPDTNSIIPL--PTNYEKDIPAYP 1552
:|| ||: :|: |.|....:||
Mouse 732 ------LPG-----------PPS-------------------------VPIQEPENQSTCLPA-- 752
Fly 1553 IPPHRYALGHGAPPHLSHHGMLEPKIEDMGMLGHGGGYAYLGSEGKPLNNGFSCCRQGGTRPPT- 1616
|...:|. .:|..: |||..|.:.......:...|| |....||
Mouse 753 -PESPFAT--RSPKKI--------KIESSGAVTVLSTTCFHSEEG------------GQEATPTK 794
Fly 1617 AEHLKDGTCLGLGIQPKEELIDEDELIDTHGNGLKPIGGVGKAKGKQKPDEIPEIVVKHEKINPM 1681
||:....|..|....|.:.| || |.
Mouse 795 AENPLTPTLSGFLESPLKYL-------DT----------------------------------PT 818
Fly 1682 FDTTDRLEKGNKTEIPECECFQSDKNPPEPGTYYTHLGTASSLMDLRREFEERCNLTGRQLRIEK 1746
....|...|..::|.|.|:|.:......| |.||||||:..::..:|...|:|....|:.:||||
Mouse 819 KSLLDTPAKKAQSEFPTCDCVEQIVEKDE-GPYYTHLGSGPTVASIRELMEDRYGEKGKAIRIEK 882
Fly 1747 IVYTGKEGKTSQGCPVAKWVIRRADLEEKILVVVKKRPGHRCIAAYIVVCMVAWDGMPRLEADNA 1811
::|||||||:|:|||:|||||||..||||:|.:|:.|.||.|..|.||:.::||:|:||...|..
Mouse 883 VIYTGKEGKSSRGCPIAKWVIRRHTLEEKLLCLVRHRAGHHCQNAVIVILILAWEGIPRSLGDTL 947
Fly 1812 YKNLIPKLNKYGLPTTRRCATNENRTCACQGLDPESSGASYSFGCSWSMYYNGCKYARSKTVRKF 1876
|:.|...|.|||.||:|||..|::|||||||.||.:.|||:|||||||||:||||||||||.|||
Mouse 948 YQELTDTLRKYGNPTSRRCGLNDDRTCACQGKDPNTCGASFSFGCSWSMYFNGCKYARSKTPRKF 1012
Fly 1877 RLSVKS--EEAAIEDHMNLIATLLAPVFKQVCPRSYDNQTKYEHEASDCRLGLEPGKPFSGVTAC 1939
||:..: ||..:.:....:||.:||::|::.|::|.||...|..|.||||||:.|:||||||||
Mouse 1013 RLTGDNPKEEEVLRNSFQDLATEVAPLYKRLAPQAYQNQVTNEDVAIDCRLGLKEGRPFSGVTAC 1077
Fly 1940 LDFCAHSHRDLHNMQDGCTVHVALLKPGNRDT-RLPDDEQFHVLPLYTMDGTDEFESVEGQRDKH 2003
:|||||:|:|.||:.:||||...|.|..||.. ::|:|||.||||||.|..||||.|.|.|..|.
Mouse 1078 MDFCAHAHKDQHNLYNGCTVVCTLTKEDNRCVGQIPEDEQLHVLPLYKMASTDEFGSEENQNAKV 1142
Fly 2004 RTGAVQMLDKFPCEVRVRSTPLIPCRRH---------GKKRKDGDEAAPPDG-DQDAV---GDAN 2055
.:||:|:|..||.|||....|...||:. .||:...::.:.|:. .|:|: |...
Mouse 1143 SSGAIQVLTAFPREVRRLPEPAKSCRQRQLEARKAAAEKKKLQKEKLSTPEKIKQEALELAGVTT 1207
Fly 2056 SQSSSSNGAQSQTQANNQQSSPPALGTA---HIK--KENGNGVNANGASSKSKGKGKSNQSNNSS 2115
....|..|..| |||..|:|... |.. |.:||.| ..|
Mouse 1208 DPGLSLKGGLS------QQSLKPSLKVEPQNHFSSFKYSGNAV-------------------VES 1247
Fly 2116 ASTPGSAPPSTPSPRCQTPVTNNPSPAGSAFSTPPVHGSNANPQSNGGQGTGNQPGQLMSSNSSL 2180
.|..||..|| :|....|.:| .|...| ||| |.|.|.
Mouse 1248 YSVLGSCRPS------------DPYSMSSVYS---YHSRYA------------QPG-LASVNG-- 1282
Fly 2181 MNMATMIDTFTDAQLQSNQISSTVLDSPYSYDYQTASYIDSRNYYGQWPT-----PHAPMGMQAQ 2240
..|.|: :.|..||| :|: |...:|..|
Mouse 1283 ------------------------FHSKYT--------LPSFGYYG-FPSSNPVFPSQFLGPSA- 1313
Fly 2241 VGGLGGGGPGGTVAGVPPLTPSTPTAQPQLGVPPATSIAGGTTTGAPTGALPATAPPTATPTQLE 2305
.|.||.||:....|.|
Mouse 1314 ---WGHGGSGGSFEKKPDL---------------------------------------------- 1329
Fly 2306 TSNGYGPGNYQTLVSNPASNLTNPGGVTTEVQQQHQQAQQQSALTGGVGPGGLPVVGGAP-GDLK 2369
:...|..| |..|||. .:|.
Mouse 1330 ---------------HALHNSLN------------------------------PAYGGAEFAELP 1349
Fly 2370 GRLVSEENPDSTTLVNHHHHHHNLTESKLTALTAMQPMTNLAPLTTSHHPQEGFVKPKPPPSDYT 2434
|:.|:.:| ||.: .||.|..: |.|.:|.
Mouse 1350 GQAVATDN------------HHPI----------------------PHHQQPAY----PGPKEYL 1376
Fly 2435 AQYTAQYPNNYQMYPPPPPPPHSAYSAYDAYQNMNYNYGYHQAYSPYGMYPQQTPPP-------- 2491
.|...|::|....|...|.| :..||....| .|.....|....|
Mouse 1377 ------LPKVPQLHPASRDPSPFAQS------SSCYNRSIKQ--EPIDPLTQAESIPRDSAKMSR 1427
Fly 2492 TPPP-------PSPNWNMY------GHHQTGSVNSGYGSANP------------AAGAGSLISSH 2531
||.| ||..|..| ...:|.||...:|...| :.||..|..||
Mouse 1428 TPLPEASQNGGPSHLWGQYSGGPSMSPKRTNSVGGNWGVFPPGESPTIVPDKLNSFGASCLTPSH 1492
Fly 2532 GSVASAGVGLQKAMVPVPGPLHHQQQQVLQQQQQQQQQQQQQQQQQQQQQQQQVQQLQQEAPQTI 2596
...:..|:...:. ||.||...
Mouse 1493 FPESQWGLFTGEG--------------------------------------------QQSAPHAG 1513
Fly 2597 LP---------DLSNGQ---TNSDTVATPTPTGDSSSNDAGPGNPG-----------AGNQAPAS 2638
.. ...||. |.......|...|....|.|..|.|| ...:.|..
Mouse 1514 ARLRGKPWSPCKFGNGTSALTGPSLTEKPWGMGTGDFNPALKGGPGFQDKLWNPVKVEEGRIPTP 1578
Fly 2639 GAGAATTA-----PPIAS---------------------------PGSTNSTKIEPIGEVAEINE 2671
||.....| .|::| |.|....|.|..|...|.:|
Mouse 1579 GANPLDKAWQAFGMPLSSNEKLFGALKSEEKLWDPFSLEEGTAEEPPSKGVVKEEKSGPTVEEDE 1643
Fly 2672 ------NIEAFQDPQMGGVAIALNHGSVLIECAKHEMHATTAVRRPDRHHPTRMTLIFYQHRNLN 2730
:...|.|..:||||:|..|.|:|||||:.|:||||.:::|:|.||||::|:||||:|||
Mouse 1644 EELWSDSEHNFLDENIGGVAVAPAHCSILIECARRELHATTPLKKPNRCHPTRISLVFYQHKNLN 1708
Fly 2731 RCRHGIDEWEEKMRVKKINTDLDNKAKEERERLIKKAAGEDMDELDEDALMQDEPVPIKKESSAN 2795
:..||:..||.||: .|..:|::.:|...:...|: :|:...
Mouse 1709 QPNHGLALWEAKMK------QLAERARQRQEEAARLGLGQ-------------------QEAKLY 1748
Fly 2796 GQQLKNGASGSKKKKSSDSKKSQANEQSKNEKVALHAPT---LTTTSWTTLFPTHP 2848
|::.|.|.:...:.:..:.|.:....| ||..|| :|.:|:.....|.|
Mouse 1749 GKKRKWGGAMVAEPQHKEKKGAIPTRQ------ALAMPTDSAVTVSSYAYTKVTGP 1798
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