Protein Alignment Pgant6 and GALNT14

DIOPT Version :10

• Sequence 1: NP_647749.2
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001240755.1
• Gene: GALNT14 / 79623
• HGNCID: 22946
• Length: 557
• Species: Homo sapiens
• Alignment Length: 483
• Identity: 164/483 - (33%)
• Similarity: 246/483 - (50%)
• Gaps: 57/483 - (11%)

  Fly   192 CRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETY 256
            |....|...||..|:||.|:||..|.|:|::.|::||:|..|::|||||||.|:.....|:|
Human   106 CTLLVYCTDLPPTSIIITFHNEARSTLLRTIRSVLNRTPTHLIREIILVDDFSNDPDDCKQL--- 167

  Fly   257 IAEHFKWVRVVRLPR--------RTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIA 313
                      ::||:        |.||:.:|..||..|....|.|||||.|.|.:||.|||..:.
Human   168 ----------IKLPKVKCLRNNERQGLVRSRIRGADIAQGTTLTFLDSHCEVNRDWLQPLLHRVK 222

  Fly   314 LNKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDWEFFYKRLPLLPEDLKH---PADPFKSPIMAG 375
            .:....|||.||:|:...|.|.......||.|||...::...|.||....   |.:|.::||:||
Human   223 EDYTRVVCPVIDIINLDTFTYIESASELRGGFDWSLHFQWEQLSPEQKARRLDPTEPIRTPIIAG 287

  Fly   376 GLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQ---PS 437
            |||.|.:.:|..||.||..:||||||.:|:||::|||||.:...||||:||::|  :.|.   |.
Human   288 GLFVIDKAWFDYLGKYDMDMDIWGGENFEISFRVWMCGGSLEIVPCSRVGHVFR--KKHPYVFPD 350

  Fly   438 PRKGDYLHKNYKRVAEVWMDEYKNYLYSHGDGLYESVDP-GDLTEQKAIRTKLNCKSFKWFMEEV 501
            .....|: ||.||.|||||||||.|.|:......|.  | |::..:..:|..|.|:||||::|.:
Human   351 GNANTYI-KNTKRTAEVWMDEYKQYYYAARPFALER--PFGNVESRLDLRKNLRCQSFKWYLENI 412

  Fly   502 AFDLMKTYPPVDPPSYAMGALQNVGNQNLCLDTLGRKKHNK----MGMYACADNIKTPQRTQFWE 562
                   ||.:..|..:.....|:..:..||::  ::::|:    :.:..||.......::|.|.
Human   413 -------YPELSIPKESSIQKGNIRQRQKCLES--QRQNNQETPNLKLSPCAKVKGEDAKSQVWA 468

  Fly   563 LSWKRDLRLRRKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKHGTEGRRCLELLPF 627
            .::.:  ::.:::.||.|......|||.|..|.:....|.|.....|  ::| .....||:...|
Human   469 FTYTQ--QILQEELCLSVITLFPGAPVVLVLCKNGDDRQQWTKTGSH--IEH-IASHLCLDTDMF 528

  Fly   628 ------SQEVVANKCDTDNRFQQWNFGS 649
                  .:|:|.|.|::....|.|:..|
Human   529 GDGTENGKEIVVNPCESSLMSQHWDMVS 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_647749.2	pp-GalNAc-T	205..502	CDD:133004	127/311 (41%)
		beta-trefoil_Ricin_Pgant9-like	515..648	CDD:467340	30/142 (21%)
GALNT14	NP_001240755.1	pp-GalNAc-T	119..413	CDD:133004	127/318 (40%)
		beta-trefoil_Ricin-like	418..557	CDD:483949	31/146 (21%)