DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant6 and Galnt15

DIOPT Version :9

Sequence 1:	NP_001261342.1	Gene:	Pgant6 / 38346	FlyBaseID:	FBgn0035375	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	XP_006519762.1	Gene:	Galnt15 / 78754	MGIID:	1926004	Length:	652	Species:	Mus musculus

Alignment Length:	674	Identity:	198/674 - (29%)
Similarity:	313/674 - (46%)	Gaps:	87/674 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLLLISLTLFVLITSWISSTPYTNKPVHHGVEPVPEKAGLSGDVKVKVPAIKQPEPQKPQEPDFE 78
            |||.::|...:::...:...|.|   :|..|.....|.  |.|...::......|.....|.:.:
Mouse    17 LLLFLTLGCVLMMVILLHPPPPT---LHQAVTAQASKH--SPDTGYRLDFGDSQEWVLEAETEGD 76

  Fly    79 EDPELQKIDEPEPVEEE-----VDNPHPADDEPQQQPQEELQMAAPA-----DASVKKDWHDYTF 133
            |...|..:.....::|:     |.:|.....:.|.:.|...|.....     :.:::|||.
Mouse    77 EYSLLDGLPSFISLQEDQLLVAVASPRARRSQSQGRRQGSYQFIKHRSRRWDEEALEKDWR---- 137

  Fly   134 MEKDAKRVGLGEGGKASTLDDESQRDLEKRMSLENGFNALLSDSISVNRSVPDIRHPLCRKKEYV 198
            .|:|.               :||:..|.......:|.|..||..:.:.|.:|::|||||.::...
Mouse   138 TEEDG---------------EESEEVLTPLGPDSDGLNKPLSARLPLRRVLPEVRHPLCLQQHPT 187

  Fly   199 AKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFKW 263
            :.|||.|||:.|::|....|:|:|||:::.:|..|::|||||||.|.:|.|...|..|:| ..:.
Mouse   188 SGLPTASVILCFHDEAWPTLLRTVHSILDTAPRALLQEIILVDDLSQQELLKSALSEYVA-RLEA 251

  Fly   264 VRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVID 328
            |:::|..||.|.||||..||..||.:||:|:|:|.|.:..||.|||..||.::...|.|.|||||
Mouse   252 VKLLRSNRRLGTIGARMLGATRATGDVLVFMDAHCECHPGWLEPLLSRIADDRSRVVSPVIDVID 316

  Fly   329 HTNFHYRAQDEGARGAFDWEFFYKRLPLLPED---LKHPADPFKSPIMAGGLFAISREFFWELGG 390
            .....|.| .:..||..||:..::..||..::   |..|..|.:||::...:.|:.|.:|...|.
Mouse   317 WKTLQYSA-SKLHRGTLDWKLDFRWKPLGEQEQKALPSPISPVRSPVVPREVVAVDRHYFQNTGA 380

  Fly   391 YDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRG-PRNHQPSPRKGDYLHKNYKRVAEV 454
            ||..|.:...|..|:|||.|:|||.:...||||:|||||. ..:.:|.|   :...||...:||.
Mouse   381 YDPLLSLGDSENLEMSFKAWLCGGSVEILPCSRVGHIYRSQDASSRPDP---EVALKNKIIIAET 442

  Fly   455 WMDEYKNYLYSHGDGLY--ESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPPSY 517
            |:..:|...|.|....:  ..|...|.||:..::.:|.|::|.||:..|..:|   ||....|.:
Mouse   443 WLSSFKETFYRHIPEAFTLSKVAKPDCTERLKLQRRLGCRTFHWFLANVYPEL---YPSDHRPRF 504

  Fly   518 AMGALQNVGNQNLCLD------------TLGRKKHNK------MGMYACADNIKTPQRTQFWELS 564
            : |.|.|.| ..||.|            ||....:|:      :.|.....:.:..:.|...|:.
Mouse   505 S-GKLHNTG-FGLCADCQADGDILGCPMTLAPCSNNRQQQGTLLAMLTATPSAQNLEHTGRKEIL 567

  Fly   565 WKRDLRLRRKKECLDVQIWDANAPVWLWDCHSQG---GNQYWYYDYRHK-QLKHGTEGRRCLE-- 623
            :....||     |.||:    ...|.|.:|..:|   ..|:|  |::.. .:.|...| :|:|
Mouse   568 FGGPQRL-----CFDVR----GGRVILQNCTEEGPAIHQQHW--DFQEDGMIIHVLSG-KCMEAG 620

  Fly   624 LLPFSQEVVANKCDTDNRFQQWNF 647
            :.|.::::...:|| ....|.|.|
Mouse   621 VQPSNKDLYLRQCD-GKTSQLWRF 643

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_001261342.1	BcsA	199..>413	CDD:224136	87/216 (40%)
		pp-GalNAc-T	205..502	CDD:133004	115/302 (38%)
		RICIN	520..647	CDD:238092	34/150 (23%)
		Ricin_B_lectin	520..645	CDD:279046	33/148 (22%)
Galnt15	XP_006519762.1	pp-GalNAc-T	194..492	CDD:133004	115/302 (38%)
Galnt15	XP_006519762.1	Ricin_B_lectin	504..641	CDD:366226	33/151 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842547
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740