Protein Alignment Pgant6 and galnt10

DIOPT Version :10

• Sequence 1: NP_647749.2
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001072444.1
• Gene: galnt10 / 779898
• XenbaseID: XB-GENE-1010672
• Length: 603
• Species: Xenopus tropicalis
• Alignment Length: 593
• Identity: 280/593 - (47%)
• Similarity: 365/593 - (61%)
• Gaps: 45/593 - (7%)

  Fly    93 EEEVDNPHPADDEPQQQPQEELQMAAPADASV------KKDWHDYTFMEKDAKRVGLGEGGKAST 151
            |:::::....|.|   :.:.|:....|.|..|      |||||:|..:.|:::::|.||.||...
 Frog    33 EKQLESAGARDLE---KARGEVLFVKPRDEKVNEKVPEKKDWHNYEQIRKESEQIGNGEQGKPFP 94

  Fly   152 LDDESQRDLEKRMSLENGFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLS 216
            :.|....|...|   |||||..:||.||:|||:||||:..|:.|.|.:|||..||||.|:||..|
 Frog    95 MTDADHVDQAYR---ENGFNIFVSDKISLNRSLPDIRNSNCKNKFYFSKLPNTSVIIPFHNEGWS 156

  Fly   217 VLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFKWVRVVRLPRRTGLIGARAA 281
            .|:|:|||::|||||||:.||:||||:||:.:|...||.|:| :|..|::||..:|.|||..|..
 Frog   157 SLLRTVHSVLNRSPPELIAEIVLVDDYSDKAHLKSRLEKYMA-NFPKVKIVRTKKREGLIRTRML 220

  Fly   282 GARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQ-DEGARGAF 345
            ||..|:.|||.|||||.|||.|||||||:|:..|.:|.|||.|||||..||.|..| .:..||||
 Frog   221 GATVASGEVLTFLDSHCEANVNWLPPLLDPLVQNYKTVVCPMIDVIDSDNFGYVTQAGDAMRGAF 285

  Fly   346 DWEFFYKRLPLLPEDLK-HPADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKI 409
            |||.||||:|:.||..| .|:|||.||:||||||||:||:||:|||||.||:||||||||:|||:
 Frog   286 DWEMFYKRIPIPPELQKGDPSDPFDSPVMAGGLFAINREWFWQLGGYDPGLEIWGGEQYEISFKV 350

  Fly   410 WMCGGEMYDAPCSRIGHIYRGPRNHQPSPRK---GDYLHKNYKRVAEVWMDEYKNYLYSHGDGLY 471
            |||||.|.|:||||:|||||     :..|.|   |..|.:|.|||||||||||..|:|..... |
 Frog   351 WMCGGRMVDSPCSRVGHIYR-----KYVPYKVPAGVSLARNLKRVAEVWMDEYAEYIYQRRPD-Y 409

  Fly   472 ESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPPSYAMGALQNVGNQNLCLDTLG 536
            ..:..||:..||.:|.||.|:.|||||.|:|:||.|.||||:.|..|.|.::|| ..::|:..
 Frog   410 RHLSVGDVAAQKELRRKLQCRDFKWFMNEIAWDLPKYYPPVELPPAAWGEIRNV-RMDMCVGV-- 471

  Fly   537 RKKHNKMG----MYAC--ADNIKTPQRTQFWELSWKRDLR----LRRKKECLDVQIWDANAPVWL 591
              ||...|    :.||  ..|..|....|.:.|.|:.|:|    ....|.|.|..  ...:||.|
 Frog   472 --KHVTSGTEIRLEACNKGRNSDTWGARQVFTLGWREDIRPGIPQHTMKSCFDAV--SQTSPVTL 532

  Fly   592 WDCHSQGGNQYWYYDYRHKQLKHGTEGRRCLELLPFSQEVVANKCDTDNRFQQWNFGSFNKTALD 656
            :|||...|||.|.| .|.|.:.|.| ...|::......::..|||:..:..|||.|...|.|.|:
 Frog   533 FDCHGMKGNQLWKY-RRDKTVYHPT-SNSCMDCNEGEYKIFMNKCNPSSPTQQWTFEHINSTILE 595

  Fly   657 --NYSQDL 662
              |.::||
 Frog   596 AFNRNKDL 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_647749.2	pp-GalNAc-T	205..502	CDD:133004	178/301 (59%)
		beta-trefoil_Ricin_Pgant9-like	515..648	CDD:467340	43/142 (30%)
galnt10	NP_001072444.1	pp-GalNAc-T	145..440	CDD:133004	178/301 (59%)
		beta-trefoil_Ricin-like	451..600	CDD:483949	48/157 (31%)