DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant6 and Galntl5

DIOPT Version :9

Sequence 1:	NP_001261342.1	Gene:	Pgant6 / 38346	FlyBaseID:	FBgn0035375	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_080725.2	Gene:	Galntl5 / 67909	MGIID:	1915159	Length:	431	Species:	Mus musculus

Alignment Length:	426	Identity:	160/426 - (37%)
Similarity:	239/426 - (56%)	Gaps:	45/426 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 HPADDEPQQQPQEELQMAAPADASVKKDWHDYTFMEKDAKRVGLGEGGKASTLDDESQRDLEKRM 164
            |...::..:..:|||.    ...|:.|:.|..|...:|.            |.|:.:..|.|...
Mouse    28 HLEQEDMLENEKEELL----KKRSLGKNAHQQTRHSEDV------------THDEVNFSDPELIQ 76

  Fly   165 SLEN-GFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINR 228
            .|.. |.||::|..:.:.|.|||.|..:|::|.|...|||.|:||.||||..:.|:|:|.|::|.
Mouse    77 GLRRYGLNAIMSRRLGIEREVPDSRDKICQQKHYPFNLPTASIIICFYNEEFNTLLRAVSSVVNL 141

  Fly   229 SPPELMKEIILVDDHSDREYLGKELETYIAEHFKW-VRVVRLPRRTGLIGARAAGARNATAEVLI 292
            ||..|::|||||||.|:.:.|..:|:.|: |.|:. |:::|..:|.|||.::..||..|:.::|:
Mouse   142 SPQHLLEEIILVDDMSEFDDLKDKLDYYL-EIFRGKVKLIRNKKREGLIRSKMIGASRASGDILV 205

  Fly   293 FLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDWE--------F 349
            |||||.|.|..||.|||..||.:.:..|||.||||:.....|.|... .||||||.        |
Mouse   206 FLDSHCEVNRVWLEPLLHAIAKDHKMVVCPIIDVINELTLDYMAAPI-VRGAFDWNLNLRWDNVF 269

  Fly   350 FYKRLPLLPEDLKHPADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGG 414
            .|:.     :..:.|:.|.:||.|.||:|||:|.:|.|||.||.|:||.|||..|||.:||||||
Mouse   270 AYEL-----DGPEGPSTPIRSPAMTGGIFAINRHYFNELGQYDNGMDICGGENVELSLRIWMCGG 329

  Fly   415 EMYDAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRVAEVWMDEYK-NYLYSHGDGLYESVDPGD 478
            :::..||||:|:..:....|:.:.:..  |.:|..||..||:|||| |:........|  |..|:
Mouse   330 QLFILPCSRVGYNSKALSQHRRANQSA--LSRNLLRVVHVWLDEYKGNFFLQRPSLTY--VSCGN 390

  Fly   479 LTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDP 514
            ::|:..:|.:|.||||:|:::.:       :|.::|
Mouse   391 ISERVELRKRLGCKSFQWYLDNI-------FPELEP 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_001261342.1	BcsA	199..>413	CDD:224136	101/222 (45%)
		pp-GalNAc-T	205..502	CDD:133004	129/306 (42%)
		RICIN	520..647	CDD:238092
		Ricin_B_lectin	520..645	CDD:279046
Galntl5	NP_080725.2	Catalytic subdomain A	114..224		53/110 (48%)
		pp-GalNAc-T	118..414	CDD:133004	129/313 (41%)
		Glyco_tranf_2_2	118..380	CDD:287123	118/270 (44%)
		Catalytic subdomain B	282..344		36/61 (59%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842586
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740