Protein Alignment Pgant6 and Galntl5

DIOPT Version :10

• Sequence 1: NP_647749.2
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_080725.2
• Gene: Galntl5 / 67909
• MGIID: 1915159
• Length: 431
• Species: Mus musculus
• Alignment Length: 426
• Identity: 160/426 - (37%)
• Similarity: 239/426 - (56%)
• Gaps: 45/426 - (10%)

  Fly   100 HPADDEPQQQPQEELQMAAPADASVKKDWHDYTFMEKDAKRVGLGEGGKASTLDDESQRDLEKRM 164
            |...::..:..:|||.    ...|:.|:.|..|...:|.            |.|:.:..|.|...
Mouse    28 HLEQEDMLENEKEELL----KKRSLGKNAHQQTRHSEDV------------THDEVNFSDPELIQ 76

  Fly   165 SLEN-GFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINR 228
            .|.. |.||::|..:.:.|.|||.|..:|::|.|...|||.|:||.||||..:.|:|:|.|::|.
Mouse    77 GLRRYGLNAIMSRRLGIEREVPDSRDKICQQKHYPFNLPTASIIICFYNEEFNTLLRAVSSVVNL 141

  Fly   229 SPPELMKEIILVDDHSDREYLGKELETYIAEHFKW-VRVVRLPRRTGLIGARAAGARNATAEVLI 292
            ||..|::|||||||.|:.:.|..:|:.|: |.|:. |:::|..:|.|||.::..||..|:.::|:
Mouse   142 SPQHLLEEIILVDDMSEFDDLKDKLDYYL-EIFRGKVKLIRNKKREGLIRSKMIGASRASGDILV 205

  Fly   293 FLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDWE--------F 349
            |||||.|.|..||.|||..||.:.:..|||.||||:.....|.|... .||||||.        |
Mouse   206 FLDSHCEVNRVWLEPLLHAIAKDHKMVVCPIIDVINELTLDYMAAPI-VRGAFDWNLNLRWDNVF 269

  Fly   350 FYKRLPLLPEDLKHPADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGG 414
            .|:.     :..:.|:.|.:||.|.||:|||:|.:|.|||.||.|:||.|||..|||.:||||||
Mouse   270 AYEL-----DGPEGPSTPIRSPAMTGGIFAINRHYFNELGQYDNGMDICGGENVELSLRIWMCGG 329

  Fly   415 EMYDAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRVAEVWMDEYK-NYLYSHGDGLYESVDPGD 478
            :::..||||:|:..:....|:.:.:..  |.:|..||..||:|||| |:........|  |..|:
Mouse   330 QLFILPCSRVGYNSKALSQHRRANQSA--LSRNLLRVVHVWLDEYKGNFFLQRPSLTY--VSCGN 390

  Fly   479 LTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDP 514
            ::|:..:|.:|.||||:|:::.:       :|.::|
Mouse   391 ISERVELRKRLGCKSFQWYLDNI-------FPELEP 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_647749.2	pp-GalNAc-T	205..502	CDD:133004	129/306 (42%)
		beta-trefoil_Ricin_Pgant9-like	515..648	CDD:467340	160/426 (38%)
Galntl5	NP_080725.2	Catalytic subdomain A	114..224		53/110 (48%)
		pp-GalNAc-T	118..414	CDD:133004	129/313 (41%)
		Catalytic subdomain B	282..344		36/61 (59%)