Protein Alignment Pgant6 and galnt17

DIOPT Version :10

• Sequence 1: NP_647749.2
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_696189.5
• Gene: galnt17 / 567794
• ZFINID: ZDB-GENE-110419-5
• Length: 617
• Species: Danio rerio
• Alignment Length: 696
• Identity: 208/696 - (29%)
• Similarity: 316/696 - (45%)
• Gaps: 145/696 - (20%)

  Fly     1 MRRPNLKWIVKASLLLLISLTLFVLITSWISSTPYTNKPVHHGVEPVPEKAG---LSGDVKVKVP 62
            |||    |.:   ||:|...|:...||.|......|.|.|  |.:...:..|   |:|.|
Zfish    18 MRR----WKI---LLVLNVFTVAGFITFWGKCNVRTTKGV--GQQMAVDSRGQTNLNGSV----- 68

  Fly    63 AIKQPEPQKPQEPDFEEDPELQKIDEPEPVEEEVDNPHPADDEPQQQPQEELQMAAPADASVKKD 127
                      ||.....|..|:::...|.|.
Zfish    69 ----------QETSITHDVLLKRLGSLEDVV---------------------------------- 89

  Fly   128 WHDYTFMEKDAKRVGL-------GEGGKASTLDDESQRDLEKRMSLENGFNALLSDSISVNRSVP 185
               |..:...:|.:||       |.||..:||....::: .|.:..:.|:||.|||.||::||:|
Zfish    90 ---YRQLNGLSKSLGLIEGFGGRGRGGIPATLTPAEEKE-AKFLREKYGYNAFLSDKISLDRSLP 150

  Fly   186 DIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLG 250
            |.|...|:|..:...||.:|:|.||.||.|||::|||||.:|.:|..|:||||||||:||...|.
Zfish   151 DYRPSKCKKAFFPRDLPQISIIFIFVNEALSVILRSVHSAVNHTPAHLLKEIILVDDNSDDVQLK 215

  Fly   251 KELETYIAEHFK-WVRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIAL 314
            ..||.|:.:.:. .:::||..:|.|||.||..|.:.||.||..|.|:|||....|..|:|..|..
Zfish   216 GPLEEYVNKRYPGLIKIVRNQKREGLIRARIEGWKVATGEVTGFFDAHVEFTPAWAEPVLSRIKE 280

  Fly   315 NKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDWEFF--YKRLPLLPEDLKHPADPFKSPIMAGGL 377
            |.:..:.|.||.|....|.....:....| ::||.:  |...|....|....:.|.::|.|.|..
Zfish   281 NHKRIILPSIDNIKDETFELERYENSGHG-YNWELWCMYISPPKQWWDEGDTSAPIRTPAMIGCS 344

  Fly   378 FAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGD 442
            |.::||:|.:||..|.|:|::|||..||..::|:|||.|...||||:.||.|..:.:..:  ...
Zfish   345 FVVNREYFGDLGLLDAGMDVYGGENIELGIRVWLCGGSMEVLPCSRVAHIARTKKPYHSN--IAF 407

  Fly   443 YLHKNYKRVAEVWMDEYKNYLY--------SHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFME 499
            :..:|..||||||||:||:.:|        :||      :|.||::|:.|:|.:|.||||.|:::
Zfish   408 HTRRNALRVAEVWMDQYKSNVYLAWNLPMKNHG------IDYGDVSERLALRKRLQCKSFDWYLD 466

  Fly   500 EVAFDLMKTYPPVDPPSYAMGALQNVGNQNLCLDTLGRKKHNKMGMYACADNIKTPQRTQFWELS 564
            .: :..|:.|    ..:...|.::|....:||:|. |.|:::...::.|.              .
Zfish   467 NI-YPEMRRY----NNTVFYGEIRNTNVTHLCVDQ-GIKENHTATLHPCH--------------G 511

  Fly   565 WKRDLRLRRKKE----------------C-LDVQIWDANAPVWLWDCH--SQGGNQYWYYDYRHK 610
            |...|. |..||                | :|.:|  ::.| .|.:|.  |....:.|::.....
Zfish   512 WGPQLG-RYTKEGYLFLGPLGSTGEDTRCVVDDKI--SSYP-QLLNCEKVSSVRQKTWHFAQNES 572

  Fly   611 QLKHGTEGRRCLELLP----FSQEVVANKCDTDNRFQQWNFGSFNK 652
            .:...|  .||||::|    |...::...|..    |:||..:..|
Zfish   573 IISRAT--GRCLEVVPANVYFGYALILRSCTG----QKWNIKNLMK 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_647749.2	pp-GalNAc-T	205..502	CDD:133004	121/307 (39%)
		beta-trefoil_Ricin_Pgant9-like	515..648	CDD:467340	32/155 (21%)
galnt17	XP_696189.5	pp-GalNAc-T	170..469	CDD:133004	121/308 (39%)
		beta-trefoil_Ricin_GALNT8-like	477..609	CDD:467316	32/156 (21%)