Protein Alignment Pgant6 and galnt1

DIOPT Version :10

• Sequence 1: NP_647749.2
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_687472.3
• Gene: galnt1 / 559073
• ZFINID: ZDB-GENE-030131-2360
• Length: 557
• Species: Danio rerio
• Alignment Length: 545
• Identity: 205/545 - (37%)
• Similarity: 304/545 - (55%)
• Gaps: 45/545 - (8%)

  Fly   112 EELQMAAPADASVKKDWHDYTFMEKDAKRVGLGEGGKASTLDDESQRDLEKRMSLENGFNALLSD 176
            ::.:...|...:|.:..||           |.||.||...:..:.|..: |.|...|.||.:.|:
Zfish    36 DKKERGLPGRDTVVQRPHD-----------GPGEMGKPVVIAKDQQEKM-KEMFKINQFNLMASE 88

  Fly   177 SISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVD 241
            .|::|||:||:|...|:.|.|...||..||:|:|:||..:.|:|:|||:|:|||..|::||:|||
Zfish    89 MIALNRSLPDVRLEGCKTKVYPDDLPRTSVVIVFHNEAWTTLLRTVHSVIDRSPRHLLEEIVLVD 153

  Fly   242 DHSDREYLGKELETYIAEHFKWVRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLP 306
            |.|:|::|.::||.|:.:....|||||:.:|:|||.||..||..:|.:|:.|||:|.|....||.
Zfish   154 DASERDFLKRQLEHYVRKLEVPVRVVRMEQRSGLIRARLKGASISTGQVITFLDAHCECTTGWLE 218

  Fly   307 PLLEPIALNKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDWEFFYKRLPLLPEDL-KHPAD---P 367
            |||..|.|:|:|.|||.||||....|.|.|..:...|.|:|:..::..|:...:: :...|   |
Zfish   219 PLLSRIKLDKKTVVCPIIDVISDDTFEYMAGSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLP 283

  Fly   368 FKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPR 432
            .::|.||||||:|.|::|.|:|.||.|:||||||..|:||:||.|||.:....||.:||::|...
Zfish   284 VRTPTMAGGLFSIDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKAT 348

  Fly   433 NHQPSPRKGDYLHKNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWF 497
            .:......|..::||.:|:|||||||:||:.|....|: ..||.||::.:.::|.:|.||.|.|:
Zfish   349 PYTFPGGTGQIINKNNRRLAEVWMDEFKNFFYIISPGV-TKVDYGDISTRTSLRQRLQCKPFSWY 412

  Fly   498 MEEVAFDLMKTYPPVDPPS--YAMGALQNVGNQNLCLDTLGRKKHNKMGMYAC----ADNIKTPQ 556
            :|.|       ||....|.  |::|.::|| ..|.|||.:.||::.|:|::.|    .:.:
Zfish   413 LENV-------YPDSQIPRHYYSLGEIRNV-ETNQCLDNMARKENEKVGIFNCHGMGGNQV---- 465

  Fly   557 RTQFWELSWKRDLRLRRKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKHGTEGRRC 621
                  .|:..:..:|....||||.  ..|.||.:..||...|||.|.||.....|.| ....:|
Zfish   466 ------FSYTANKEIRTDDLCLDVS--KLNGPVMMLKCHHLKGNQLWEYDPVKLSLVH-VNSNQC 521

  Fly   622 LELLPFSQEVVANKCDTDN-RFQQW 645
            |:........|.:..|... |.|||
Zfish   522 LDKASEDDSQVPSVRDCSGARSQQW 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_647749.2	pp-GalNAc-T	205..502	CDD:133004	133/300 (44%)
		beta-trefoil_Ricin_Pgant9-like	515..648	CDD:467340	41/138 (30%)
galnt1	XP_687472.3	pp-GalNAc-T	117..417	CDD:133004	134/307 (44%)
		beta-trefoil_Ricin_GALNT1	424..550	CDD:467344	40/137 (29%)