DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant6 and galnt13

DIOPT Version :9

Sequence 1:	NP_001261342.1	Gene:	Pgant6 / 38346	FlyBaseID:	FBgn0035375	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	XP_031748551.1	Gene:	galnt13 / 550031	XenbaseID:	XB-GENE-1012445	Length:	571	Species:	Xenopus tropicalis

Alignment Length:	538	Identity:	196/538 - (36%)
Similarity:	296/538 - (55%)	Gaps:	57/538 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 GLGEGGKASTLDDESQRDLEKRMSLENGFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSV 206
            |.||.|||..:..:.|..:::...: |.||.:.||.|::|||:||:|...|:.|.|..:||..|:
Frog    56 GPGELGKAVIIPKDDQEKMKELFKI-NQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSI 119

  Fly   207 IIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFKWVRVVRLPR 271
            :|:|:||..|.|:|:|||:|||||..|:.|||||||.|:|::|...||.|:......|:::|:.:
Frog   120 VIVFHNEAWSTLLRTVHSVINRSPHRLISEIILVDDSSERDFLKSPLENYVKHLEVPVKILRMEQ 184

  Fly   272 RTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRA 336
            |:|||.||..||..|..:::.|||:|.|....||.|||..|..:::|.|||.||||....|.|.|
Frog   185 RSGLIRARLRGANVAKGQIITFLDAHCECTIGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMA 249

  Fly   337 QDEGARGAFDWEFFYKRLPLLPEDL-KHPAD---PFKSPIMAGGLFAISREFFWELGGYDEGLDI 397
            ..:...|.|:|:..::..|:...:: :...|   |.::|.||||||:|.:.:|.|||.||.|:||
Frog   250 GSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDKTYFEELGTYDSGMDI 314

  Fly   398 WGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRVAEVWMDEYKNY 462
            ||||..|:||:||.|||.:....||.:||::|....:......|..::||.:|:||||||::|::
Frog   315 WGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWMDDFKDF 379

  Fly   463 LYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPPS--YAMGALQNV 525
            .|....|:.: ||.||::|:||:|..|.|..|.|::|.|       ||....|.  :::|.::||
Frog   380 FYIISPGVVK-VDYGDVSERKALRENLKCNPFSWYLETV-------YPDSQIPRRYFSLGEIRNV 436

  Fly   526 GNQNLCLDTLGRKKHNKMGMYAC----ADNIKTPQRTQFWELSWKRDLRLRRKKECLDVQIWDAN 586
             ..|.|||.:|||::.|:|::.|    .:.:          .|:..|..:|....||||.  ..|
Frog   437 -ETNQCLDNMGRKENEKVGIFNCHGMGGNQV----------FSYTADKEIRTDDLCLDVS--RLN 488

  Fly   587 APVWLWDCHSQGGNQYWYYDYRHKQLKHGTEGRRCLELLPFSQEVVANKCDTDNRFQQWNFG--- 648
            .||.:..||...|||.|.||.......|                ::...|.|.:..:...||
Frog   489 GPVIMLKCHHMRGNQLWEYDAETHTFLH----------------IITQSCLTLSNVEDGTFGPTV 537

  Fly   649 ------SFNKTALDNYSQ 660
                  :..:..|.||::
Frog   538 EFCNGRNQQRWTLRNYTR 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_001261342.1	BcsA	199..>413	CDD:224136	97/217 (45%)
		pp-GalNAc-T	205..502	CDD:133004	129/300 (43%)
		RICIN	520..647	CDD:238092	34/130 (26%)
		Ricin_B_lectin	520..645	CDD:279046	34/128 (27%)
galnt13	XP_031748551.1	pp-GalNAc-T	118..418	CDD:133004	130/307 (42%)
galnt13	XP_031748551.1	Ricin_B_lectin	431..548	CDD:395527	36/145 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910