DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant6 and Pgant35A

DIOPT Version :9

Sequence 1:	NP_001261342.1	Gene:	Pgant6 / 38346	FlyBaseID:	FBgn0035375	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_652069.2	Gene:	Pgant35A / 48775	FlyBaseID:	FBgn0001970	Length:	632	Species:	Drosophila melanogaster

Alignment Length:	546	Identity:	183/546 - (33%)
Similarity:	272/546 - (49%)	Gaps:	96/546 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 PADDEPQQQPQEELQMAAPADASVKKDWHDYTFMEKDAKRVGLGEGGKASTLDDESQRDLEKRMS 165
            ||..:|...| |:|::.                             |......|:..||:..:
  Fly    78 PAAPKPPSDP-EQLELL-----------------------------GVVRNKQDKYIRDIGYK-- 110

  Fly   166 LENGFNALLSDSISVNRSVPDIRHPLCRKKE--YVAKLPTVSVIIIFYNEYLSVLMRSVHSLINR 228
             .:.||||:|::|.:.|::||.||.:|.::|  ....||..|:::.||||:...||||:.:::.|
  Fly   111 -HHAFNALVSNNIGLFRAIPDTRHKVCDRQETTEAENLPQASIVMCFYNEHKMTLMRSIKTVLER 174

  Fly   229 SPPELMKEIILVDDHSDREYLGKELETYIAEHFKW--VRVVRLPRRTGLIGARAAGARNATAEVL 291
            :|..|::||||||||||...|...|...:....|:  :|.::..:|.|||.:|..|||.|..:||
  Fly   175 TPSYLLREIILVDDHSDLPELEFHLHGDLRARLKYDNLRYIKNEQREGLIRSRVIGAREAVGDVL 239

  Fly   292 IFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDW--EFFYKRL 354
            :|||||:|.|..||.|||..|.....|...|.||:|:...|.| ......||.|:|  .|.::.|
  Fly   240 VFLDSHIEVNQQWLEPLLRLIKSENATLAVPVIDLINADTFEY-TPSPLVRGGFNWGLHFRWENL 303

  Fly   355 P----LLPEDLKHPADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGE 415
            |    .:|||.:   .||:||.|||||||::|::|..||.||..:||||||..|:||:.|.|||.
  Fly   304 PEGTLKVPEDFR---GPFRSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEISFRAWQCGGA 365

  Fly   416 MYDAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLT 480
            :...||||:|||:| .|....||...:.:.||..|:|.||||:||:|...| :.:.::.|.||::
  Fly   366 IKIVPCSRVGHIFR-KRRPYTSPDGANTMLKNSLRLAHVWMDQYKDYYLKH-EKVPKTYDYGDIS 428

  Fly   481 EQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPP------SYAMGALQ---------------N 524
            ::..:|.:|.|:.|.|:::.|       ||.:..|      |.|....|               .
  Fly   429 DRLKLRERLQCRDFAWYLKNV-------YPELHVPGEESKKSAAAPIFQPWHSRKRNYVDTFQLR 486

  Fly   525 VGNQNLCLDTLGR------KKHNKMGMYACADNIKTPQRTQFWELSWKRDLRLRRKKECLDVQIW 583
            :....||...:..      ||.:.:.:..|.   :||  .|.|..:.|.::.| .|..||:.
  Fly   487 LTGTELCAAVVAPKVKGFWKKGSSLQLQTCR---RTP--NQLWYETEKAEIVL-DKLLCLEA--- 542

  Fly   584 DANAPVWLWDCHSQGGNQYWYYDYRH 609
            ..:|.|.:..||...|:|.|    ||
  Fly   543 SGDAQVTVNKCHEMLGDQQW----RH 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_001261342.1	BcsA	199..>413	CDD:224136	96/221 (43%)
		pp-GalNAc-T	205..502	CDD:133004	128/304 (42%)
		RICIN	520..647	CDD:238092	24/111 (22%)
		Ricin_B_lectin	520..645	CDD:279046	24/111 (22%)
Pgant35A	NP_652069.2	pp-GalNAc-T	151..450	CDD:133004	129/311 (41%)
		RICIN	489..610	CDD:214672	23/89 (26%)
		RICIN	490..609	CDD:238092	23/88 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457041
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D60373at6656
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850