DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant6 and galnt7

DIOPT Version :9

Sequence 1:	NP_001261342.1	Gene:	Pgant6 / 38346	FlyBaseID:	FBgn0035375	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	XP_012814191.2	Gene:	galnt7 / 407859	XenbaseID:	XB-GENE-950785	Length:	719	Species:	Xenopus tropicalis

Alignment Length:	733	Identity:	233/733 - (31%)
Similarity:	335/733 - (45%)	Gaps:	190/733 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SLLLLISLTLFVLI-TSWISS-------------------TPYTNKPV--HHGVEPVPEKAGLSG 55
            |||:|.:..:|::| ||:.||                   .|..|.|.  .|.|.|.|...|
Frog    77 SLLVLATFLMFLIIWTSFSSSGSTESRLQREENPNLPQAVKPDANAPKDDFHPVVPWPRVEG--- 138

  Fly    56 DVKVKVPAIKQPEPQKPQEPDFEEDPELQKIDEPEPVEEE---------------------VDNP 99
             |:|.:.:|::...::     .|:|....|::..|.|.|:                     :.|.
Frog   139 -VEVNLDSIRKKNKER-----LEQDHLEAKVNNQEHVMEKQYLTFKPQTHIYSDPVLRPGILGNL 197

  Fly   100 HPADDEPQQQPQEELQMAAPADASVKKDWHDYTFMEKDAKRVGLGEGGKASTLDDESQRDLEKRM 164
            .|.:.|||                              ....|.|||||...|..: .:|..|..
Frog   198 EPKEPEPQ------------------------------GVVGGPGEGGKPFELGPD-YKDAVKAS 231

  Fly   165 SLENGFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRS 229
            ..|.|||.:.||.||::|::.|:||..|:...|...|.|.||:|:|:||..|.|:|::||:|.|:
Frog   232 IKEFGFNMVASDMISMDRTINDLRHEECKYWNYDENLLTSSVVIVFHNEGWSTLVRTIHSVIKRT 296

  Fly   230 PPELMKEIILVDDHSDREYLGKELETYIAEHFKWVRVVRLPRRTGLIGARAAGARNA-TAEVLIF 293
            |.:.:.||:::||.|::|:|...|:.|:.:....|:|.|..||.|||.||:.||..| ..:|||:
Frog   297 PRQYLAEIVMIDDFSNKEHLKGRLDEYLKQWNGLVKVFRNERREGLIQARSIGAEKAKLGQVLIY 361

  Fly   294 LDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQDEG-----ARGAFDWEFFYKR 353
            ||:|.|...||..||:.|||.::.....|.|||||...:....|..|     ||||:||...:||
Frog   362 LDAHCEVGINWYAPLIAPIAKDRTICTVPLIDVIDGNTYELIPQAGGDEDGFARGAWDWSMLWKR 426

  Fly   354 LPLLPEDLKH---PADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGE 415
            :||...:..|   ..:|::||.||||||||.|::|:|||.||.||.|||||.:|:|:|||.|||:
Frog   427 VPLTSREKAHRKAKTEPYRSPAMAGGLFAIERDYFFELGLYDPGLQIWGGENFEISYKIWQCGGK 491

  Fly   416 MYDAPCSRIGHIYR--GPRNHQPSPRKGDYLH-----KNYKRVAEVWMDEYKNYLYSHGDGLYES 473
            :...||||:|||||  |.:.: |:|   .|:.     |||.||.|||.||||:|.|:..... ::
Frog   492 LLFTPCSRVGHIYRLHGWQGN-PTP---VYVGASPTLKNYIRVVEVWWDEYKDYFYASRPET-KA 551

  Fly   474 VDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPPSYAMGALQNVGNQNLCLDTLGRK 538
            :..||:...|..|...|||||||||||:|:|:.| |.|:.|.:...|.::.. ..|.|:|::|
Frog   552 LPYGDIGPLKKFREDHNCKSFKWFMEEIAYDITK-YFPLPPKNVEWGEIRGF-ETNYCIDSMG-- 612

  Fly   539 KHNKMGMYACADNIKTPQRTQFWELSWKRDLRLRRKKECLDVQIWDANAPVWLWDCHSQGGNQY- 602
             |...|:                                           |.|..||..||||.
Frog   613 -HTNGGI-------------------------------------------VELGGCHRMGGNQLF 633

  Fly   603 ------------------------------------WYYDYRHKQLKHGTEGRRCLELLPFSQEV 631
                                                |.|.....:..|.:.| :||:......:|
Frog   634 RINEANQLMQYDQCLYKGPDGTQVMLTHCNLKEFLEWQYFKNMHRFLHISTG-KCLDRSEVLHQV 697

  Fly   632 VANKCDTDNRFQQWNFGS 649
            ..:.||.:...|:|...:
Frog   698 FLSDCDANKPTQKWEMNN 715

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_001261342.1	BcsA	199..>413	CDD:224136	101/222 (45%)
		pp-GalNAc-T	205..502	CDD:133004	144/312 (46%)
		RICIN	520..647	CDD:238092	26/163 (16%)
		Ricin_B_lectin	520..645	CDD:279046	25/161 (16%)
galnt7	XP_012814191.2	pp-GalNAc-T	272..580	CDD:133004	144/312 (46%)
galnt7	XP_012814191.2	Ricin_B_lectin	596..711	CDD:395527	25/162 (15%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48703
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920