Protein Alignment Pgant6 and galnt6

DIOPT Version :10

• Sequence 1: NP_647749.2
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_998361.1
• Gene: galnt6 / 406477
• ZFINID: ZDB-GENE-040426-2272
• Length: 619
• Species: Danio rerio
• Alignment Length: 736
• Identity: 213/736 - (28%)
• Similarity: 313/736 - (42%)
• Gaps: 228/736 - (30%)

  Fly     9 IVKASLLLLISLTLFVLITSWISSTPY----TNK---------------------PVHHGVE--P 46
            ||..:|.:||.:.|...:.|.....|:    :||                     ||...||  |
Zfish    14 IVGGTLFMLILVVLQRDVNSGALQDPWLQDLSNKKERVFEMVRGAVNNFAFQIGAPVRPSVEVQP 78

  Fly    47 VPEKAGLSG-----DVKVKVPAIKQPEPQKPQEPDFEEDPELQKIDEPEPVEEEVDNPHPADDEP 106
            .|::...||     ::|   |.|::| |:.||.|.                         ||..|
Zfish    79 TPDRNCPSGFYTQRELK---PWIERP-PENPQAPG-------------------------ADGVP 114

  Fly   107 QQQPQEELQMAAPADASVKKDWHDYTFMEKDAKRVGLGEGGKASTLDDESQRDLEKRMSLENGFN 171
            .|                      |..|.|:.::              |.|..:.:..     ||
Zfish   115 FQ----------------------YDRMTKEEEK--------------EKQEGMTRHC-----FN 138

  Fly   172 ALLSDSISVNRSV-PDIRHPLC--RKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPEL 233
            ...||.||::|:: .|.|.|.|  ||......|||.||||:|:||..|.|:|:|:|:::.||...
Zfish   139 QFASDRISLHRTLGDDTRPPECVDRKFRRCPALPTTSVIIVFHNEAWSTLLRTVYSVLHTSPAAF 203

  Fly   234 MKEIILVDDHSDREYLGKELETYIAEHFKWVRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHV 298
            :||||:|||.|..|:|..:||.|: :..|.|:|||.|.|.|||.||..||..|..|:|.|||:|.
Zfish   204 LKEIIMVDDASTAEHLHGKLEEYV-KALKIVKVVRQPERKGLITARLLGASKAEGEILTFLDAHC 267

  Fly   299 EANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHY-------RAQDEGARGAFDWE--FFYKRL 354
            |..:.||.|||..|.......|.|.|..||...|.:       ||.:   ||.|||.  |.::.:
Zfish   268 ECFHGWLEPLLARIVEEPTAVVSPEITTIDLNTFQFHKPVATARAHN---RGNFDWSLTFGWEGI 329

  Fly   355 PLLPEDLKHPAD--PFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMY 417
            |.. |:.|...:  |.|:|..|||||:||:.:|.::|.||:.::|||||..|:||::|.|||::.
Zfish   330 PDY-ENAKRKDETYPVKTPTFAGGLFSISKAYFEKIGTYDDKMEIWGGENVEMSFRVWQCGGQLE 393

  Fly   418 DAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRVAEVWMDEYKNYLYSHGDGLYESVDP---GDL 479
            ..|||.:||::|....| ..|:..:.:.:|..|:||||||:||...|.......:....   ||:
Zfish   394 IIPCSVVGHVFRTKSPH-TFPKGTEVITRNQVRLAEVWMDDYKLIFYRRSQSAAKMAKEKGFGDI 457

  Fly   480 TEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPPSYA---MGALQNVGNQNLCLDTLGRKKHN 541
            :::..:|..|.||:|.|::..|       ||....|..:   .|||:|.|.|
Zfish   458 SDRLKLREDLQCKNFSWYLSNV-------YPEAFVPDLSPVKFGALKNRGAQ------------- 502

  Fly   542 KMGMYACADNIKTPQRTQFWELSWKRDLRLRRKKECLDV-QIWDANAPVWLWDCHSQGGNQYWYY 605
                                              :|||| :..:...||.::.||:.|||||:.|
Zfish   503 ----------------------------------QCLDVGESNNGGKPVIMYTCHNMGGNQYFEY 533

  Fly   606 DYRHKQLKHGTEGRRCLELLPFSQ----------------------------------------- 629
            . .||:|:|....:.||:..|:.:
Zfish   534 T-SHKELRHNIGKQLCLQASPYPEPVKIELCTLKGKGSSLAPEQEWLITEEQLLKNPSSGKCLHK 597

  Fly   630 ---EVVANKCDTDNRFQQWNF 647
               :::.:.|:.|:..|||.|
Zfish   598 KGDKILMSPCNPDDHHQQWAF 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_647749.2	pp-GalNAc-T	205..502	CDD:133004	125/310 (40%)
		beta-trefoil_Ricin_Pgant9-like	515..648	CDD:467340	34/181 (19%)
galnt6	NP_998361.1	pp-GalNAc-T	175..480	CDD:133004	126/317 (40%)
		beta-trefoil_Ricin_GALNT3-like	490..618	CDD:467313	32/175 (18%)