DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant6 and CG7579

DIOPT Version :9

Sequence 1:	NP_001261342.1	Gene:	Pgant6 / 38346	FlyBaseID:	FBgn0035375	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_648799.1	Gene:	CG7579 / 39714	FlyBaseID:	FBgn0036528	Length:	498	Species:	Drosophila melanogaster

Alignment Length:	516	Identity:	181/516 - (35%)
Similarity:	266/516 - (51%)	Gaps:	56/516 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   170 FNALLSDSISVNRSVPDIRHPLCRKKEYVA-KLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPEL 233
            :||.||:.|.:.|::.|.|.|.|.|..|.: |..|||::|....|:...|:|.::|:|.::.|.|
  Fly    18 YNAWLSERIPLKRTLEDYRDPQCLKINYSSEKTVTVSIVIAIQQEHPHTLLRGIYSVITQTSPYL 82

  Fly   234 MKEIILV-DDHSDREYLGKELETYIAEHFKWVRVVRLPRRT--GLIGARAAGARNATAEVLIFLD 295
            :|||:|| |.|.|     .:|..:|  |.|...|::|...:  |:|.||..||..||.::|:||:
  Fly    83 LKEIVLVHDGHPD-----LDLIRHI--HHKLPIVIQLEMESSKGIIHARLTGAGVATGDILVFLN 140

  Fly   296 SHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDWEFFYKRLPLLPED 360
            .|:|....|||||||||.||.:|...|.:|.|...:|.||...|..:.||||:..:..|||....
  Fly   141 GHMEVTRGWLPPLLEPILLNNQTVTEPIVDAISRESFAYRKLVEPEQLAFDWQLDHIFLPLDQHS 205

  Fly   361 LKHPADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIG 425
            ......|:.|..:.|.:|||.|::||.|||:||||..:||:..|||.|:|.|||.:...||||:|
  Fly   206 WNSLPKPYPSSQLEGRVFAIDRKWFWHLGGWDEGLRDYGGDALELSLKVWQCGGLILAVPCSRVG 270

  Fly   426 HIY-RGPRNHQPSPRKGDYL--HKNYKRVAEVWMDEYKNYLYSHGDGL----YESVD-PGDLTEQ 482
            .|| |.....|.:|.:...|  .||:|||.:||:||||.:.|.:...|    .||:| |.||
  Fly   271 IIYKRDELEAQMAPNRNPSLQVQKNFKRVVDVWLDEYKLHFYRYNPKLRNLTAESLDKPRDL--- 332

  Fly   483 KAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPPSYAMGALQNVGNQNLCLDTLG-----RKKHNK 542
               |.:||||||:|:..:||..:...:......:|.:|.:......:.||...|     ||.|:
  Fly   333 ---RRRLNCKSFEWYRSQVAPQIRNHFLHAGLTNYPIGKIMPFVAPHFCLSIKGGFPVIRKCHS- 393

  Fly   543 MGMYACADNIKTPQRTQF--WELSWKRDLRLRRKKECLDVQIWDANAPVWLWDCHSQGGNQYWYY 605
                           |.|  |.|:.:  .:|:....||||   |....|....|..:.....|:|
  Fly   394 ---------------TNFEDWTLTSR--CQLKHGNMCLDV---DYKNNVRATKCTKKLSKNPWHY 438

  Fly   606 DYRHKQLKHGTEGRRCLELLPFSQEVVANKCDTDNRFQQWNFGSFNKTALDNYSQDLVLSL 666
            :|:|....  :.|.:||::......::.:.||:|...|:|.|.......|| :.:|:.||:
  Fly   439 NYQHSSFV--SNGNKCLQIDVNKVGLILSACDSDVTEQRWMFTKVQDFKLD-HMRDICLSV 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_001261342.1	BcsA	199..>413	CDD:224136	88/217 (41%)
		pp-GalNAc-T	205..502	CDD:133004	126/307 (41%)
		RICIN	520..647	CDD:238092	31/133 (23%)
		Ricin_B_lectin	520..645	CDD:279046	30/131 (23%)
CG7579	NP_648799.1	WcaA	52..336	CDD:223539	121/296 (41%)
		pp-GalNAc-T	54..349	CDD:133004	126/307 (41%)
		RICIN	367..478	CDD:238092	31/133 (23%)
		Ricin_B_lectin	373..476	CDD:279046	29/125 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468131
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276134at2759
OrthoFinder	1	1.000	-	-		FOG0001284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850