DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant6 and CG7304

DIOPT Version :9

Sequence 1:	NP_001261342.1	Gene:	Pgant6 / 38346	FlyBaseID:	FBgn0035375	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_996098.1	Gene:	CG7304 / 39713	FlyBaseID:	FBgn0036527	Length:	563	Species:	Drosophila melanogaster

Alignment Length:	540	Identity:	174/540 - (32%)
Similarity:	272/540 - (50%)	Gaps:	51/540 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 GLGEGGKASTLD------DESQRDLEKRMSLENGFNALLSDSISVNRSVPDIRHPLCRKKEY--- 197
            ||||.|.||.|.      ||..:.....:     :|:.|::.|.:.||:||:|...|:|.||
  Fly    46 GLGENGSASYLSVPSWEIDEYTQGWRYYL-----YNSWLAERIPLRRSLPDLRDHRCQKLEYDED 105

  Fly   198 VAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHF- 261
            ..::...|:|:||.||.|.||:|::|||:.|:|..|..|:|||:||||.::...:|.....:::
  Fly   106 SDEMKPASIIMIFRNEQLVVLLRTLHSLVERTPKYLYIELILVNDHSDTDFWNDKLSLIFFDNYV 170

  Fly   262 -KWV----RVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVC 321
             :::    |::.||.:.|||.||...|..|.||.|:|:|:.||....||.|||:.||....|...
  Fly   171 HRYIHPKARILHLPEQVGLIKARNLAASEAKAENLVFVDAQVEFTNGWLSPLLDTIAEQSYTLAT 235

  Fly   322 PFIDVIDHTNFHYRAQDEGARGAFDWEFFYKRLPLLPEDLKHPADPFKSPIMAGGLFAISREFFW 386
            |.:|.:|.....|:...| .||.:||....:.:||......|...|::...:...:|||...:|.
  Fly   236 PILDNLDEQTLAYQRSIE-RRGMYDWSLTRREVPLSRARRSHLPWPYEVAAVRTSVFAIPAVWFQ 299

  Fly   387 ELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLHK----- 446
            ::..:|..|..:|..:.|||||:|..||.:...||||:||:.  |::.....|.|| |||
  Fly   300 DISNFDNNLRGFGAAELELSFKVWCTGGRIVQVPCSRVGHLQ--PKDEDYLKRYGD-LHKMGEQK 361

  Fly   447 --NYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTY 509
              |.||:.|||..:.|:.:|.:...|. ::..|||.|.:.:..:..|:|||.|:.::...| ...
  Fly   362 SRNLKRIIEVWTGDLKSAIYKYQPHLL-NISEGDLNEPRKLYKQNECQSFKEFINDITPGL-NHV 424

  Fly   510 PPVDPPSYAMGALQNVGNQNLCLDTLGRKKHNKMGMYACADNIKTPQRTQFWELSWKRDLRLRRK 574
            ..::...||.|.::.:.....|| |:..|..| :.:..|:.|    ...|.|.|::.:|||: ..
  Fly   425 AALNRTDYASGHVKTLEFPKKCL-TINAKSQN-LFLERCSTN----NTLQNWTLTYVKDLRV-AG 482

  Fly   575 KECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKHGTEGRRCLELLPFSQE--VVANKCD 637
            ..|.:|:   .|..:....|||.||.|.|:||....||...|   :|||   |:.|  :....||
  Fly   483 NICAEVR---PNLRLGYSFCHSLGGRQSWHYDSVSNQLMSNT---KCLE---FTDELNIFLAICD 538

  Fly   638 TDNRFQQWNFGSFNKTALDN 657
            ..|..|:|...:.|.:.:.:
  Fly   539 AANGKQRWILDNINLSVMQS 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_001261342.1	BcsA	199..>413	CDD:224136	76/219 (35%)
		pp-GalNAc-T	205..502	CDD:133004	109/309 (35%)
		RICIN	520..647	CDD:238092	39/128 (30%)
		Ricin_B_lectin	520..645	CDD:279046	38/126 (30%)
CG7304	NP_996098.1	WcaA	108..>231	CDD:223539	49/122 (40%)
		pp-GalNAc-T	113..417	CDD:133004	109/308 (35%)
		Ricin_B_lectin	433..546	CDD:279046	39/128 (30%)
		RICIN	435..548	CDD:238092	39/128 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468134
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276134at2759
OrthoFinder	1	1.000	-	-		FOG0001284
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11675
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850