Protein Alignment Pgant6 and Pgant5

DIOPT Version :10

• Sequence 1: NP_647749.2
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_608906.2
• Gene: Pgant5 / 326151
• FlyBaseID: FBgn0031681
• Length: 630
• Species: Drosophila melanogaster
• Alignment Length: 607
• Identity: 230/607 - (37%)
• Similarity: 335/607 - (55%)
• Gaps: 82/607 - (13%)

  Fly    78 EEDPEL----QKIDEPEPVEE-EVDNPHPADDEP-------QQQPQEELQMAAPADASVKKDWHD 130
            |.|.||    :.:|:.:.|:: |::.....|.|.       |......:.|..|  :.|.|.|
  Fly    56 EYDVELPNAERLVDDNQLVDDNEINTEKSLDGESGGALIMGQGFASGGISMTYP--SVVLKKW-- 116

  Fly   131 YTFME---KDAKRVGLGEGGKASTLDDESQRDLEKRMSLENGFNALLSDSISVNRSVPDIRHPLC 192
              |:.   ::||... ||.||...:..: .:||.|....||.||.|.||.||:|||:.|:||..|
  Fly   117 --FLAPSVQEAKGKP-GEMGKPVKIPAD-MKDLMKEKFKENQFNLLASDMISLNRSLTDVRHEGC 177

  Fly   193 RKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYI 257
            |:|.|.:||||.|::|:|:||..:.|:|:|.|:|||||..|:||||||||.|:|::|||:||.|:
  Fly   178 RRKHYASKLPTTSIVIVFHNEAWTTLLRTVWSVINRSPRALLKEIILVDDASERDFLGKQLEEYV 242

  Fly   258 AEHFKWVRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCP 322
            |:......|:|..:|:|||.||..||.:.:.||:.|||:|.|....||.|||..|..|:||.|||
  Fly   243 AKLPVKTFVLRTEKRSGLIRARLLGAEHVSGEVITFLDAHCECTEGWLEPLLARIVQNRRTVVCP 307

  Fly   323 FIDVIDHTNFHYRAQDEGARGAFDWE--FFYKRLPLLPEDLKHPAD---PFKSPIMAGGLFAISR 382
            .||||....|.|....:...|.|:|:  |.:.|:| ..|..:...|   |.::|.||||||:|.:
  Fly   308 IIDVISDETFEYITASDSTWGGFNWKLNFRWYRVP-SREMARRNNDRTAPLRTPTMAGGLFSIDK 371

  Fly   383 EFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGD----Y 443
            ::|:|:|.||||:||||||..|:||:||.|||.:...|||.:||::   |:..|....|.    .
  Fly   372 DYFYEIGSYDEGMDIWGGENLEMSFRIWQCGGILEIIPCSHVGHVF---RDKSPYTFPGGVAKIV 433

  Fly   444 LHKNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKT 508
            || |..||||||:||::::.||...|. .....||::::||:|.:|.||||:|::|.|
  Fly   434 LH-NAARVAEVWLDEWRDFYYSMSTGA-RKASAGDVSDRKALRDRLKCKSFRWYLENV------- 489

  Fly   509 YP----PVDPPSYAMGALQNVGNQNLCLDTLGRKKHNKMGMYAC----ADNIKTPQRTQFWELSW 565
            ||    |:|  .|.:|.::|...:. ||||:|||.:.|:|:..|    .:.:          .::
  Fly   490 YPESLMPLD--YYYLGEIRNAETET-CLDTMGRKYNEKVGISYCHGLGGNQV----------FAY 541

  Fly   566 KRDLRLRRKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKHGTEGRRCLELLPFSQE 630
            .:..::.....|||..  .:|.||.:..||:.||||.|.||...|.::|...| :||      |.
  Fly   542 TKRQQIMSDDLCLDAS--SSNGPVNMVRCHNMGGNQEWVYDAEEKWIRHTNTG-QCL------QR 597

  Fly   631 VVANKCDTD-------NRFQQW 645
            ...:..:|.       .:.|||
  Fly   598 ATRDDANTPLLRPCSYGKGQQW 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_647749.2	pp-GalNAc-T	205..502	CDD:133004	139/305 (46%)
		beta-trefoil_Ricin_Pgant9-like	515..648	CDD:467340	38/142 (27%)
Pgant5	NP_608906.2	pp-GalNAc-T	190..490	CDD:133004	140/312 (45%)
		beta-trefoil_Ricin_GALNT1-like	497..623	CDD:467311	39/145 (27%)