Protein Alignment Pgant6 and Galnt12

DIOPT Version :10

• Sequence 1: NP_647749.2
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001413928.1
• Gene: Galnt12 / 313233
• RGDID: 1562001
• Length: 576
• Species: Rattus norvegicus
• Alignment Length: 621
• Identity: 209/621 - (33%)
• Similarity: 290/621 - (46%)
• Gaps: 154/621 - (24%)

  Fly    88 EPEPVEEEVDNPHPADDEPQQQPQEELQMAAPADASVKKDWHDYTFMEKDAKRVGLGEGGKASTL 152
            :|.|..    .|||...|| ..|:..|    ||||                    ||..|:|..|
  Rat    44 DPVPTR----TPHPGRHEP-VLPRPPL----PADA--------------------LGAKGEAVRL 79

  Fly   153 DDESQR-DLEKRMSLENGFNALLSDSISVNRSVPDIRHPLCRKKEY-VAKLPTVSVIIIFYNEYL 215
            ..:.:. .|::.....:..|..|||.||::|.:|:..:||||:.:| ...||..||:|.||||..
  Rat    80 QLQGEELRLQEESVQRHQINIYLSDRISLHRRLPERWNPLCREVKYDYDNLPKTSVVIAFYNEAW 144

  Fly   216 SVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFKWVRVVRLPRRTGLIGARA 280
            |.|:|:|:|::..||..|::|:|||||:||||:|.:.|...:::..| ||::|..:|.||:.||.
  Rat   145 STLLRTVYSVLETSPDILLEEVILVDDYSDREHLKEPLANELSQLPK-VRLIRASKREGLVRARL 208

  Fly   281 AGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQD-EGARGA 344
            .||..|..|||.|||.|.|.:..||.|||:.|...:...|||.|||||...|.|.... |...|.
  Rat   209 LGASAARGEVLTFLDCHCECHEGWLEPLLQRIHEKESAVVCPVIDVIDWNTFEYLGNSGEPQIGG 273

  Fly   345 FDWE--FFYKRLPLLPEDL-KHPADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELS 406
            |||.  |.:..:|.....| :.|.|..:||.|||||||:|:.:|..||.||.|:::||||..|.|
  Rat   274 FDWRLVFTWHVVPQRERKLMRSPIDVIRSPTMAGGLFAVSKRYFEYLGSYDTGMEVWGGENLEFS 338

  Fly   407 FKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLHK----NYKRVAEVWMDEYKNYLYSHG 467
            |:||.|||.:...|||.:||::         |::..|...    |..|.||||||::|. ||.|.
  Rat   339 FRIWQCGGTLETHPCSHVGHVF---------PKQAPYSRSKALANSVRAAEVWMDDFKE-LYYHR 393

  Fly   468 DGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYP----PVDPPSYAMGALQNVGNQ 528
            :........||:||:|.:|.||.||.||||::.|       ||    |.|.|.: .|.|:|.|.:
  Rat   394 NPQARLEPFGDVTERKKLRAKLQCKDFKWFLDTV-------YPELHVPEDRPGF-FGMLENRGLR 450

  Fly   529 NLCLDTLGRKKHNKMGMYACADNIKTPQRTQFWELSWKRDLRLRRKKECLDVQIWDANAPVWLWD 593
            ..|||.....::|..|                                          ..|.|:.
  Rat   451 GYCLDYNPPSENNVEG------------------------------------------HQVLLYL 473

  Fly   594 CHSQGGNQYWYYDYRHKQLKHGT----------EGR------RCLELLPFSQEVV---------- 632
            ||..|.||::.|..| :::::.|          ||:      .|.:.:|.:||.|
  Rat   474 CHGMGQNQFFEYTSR-QEIRYNTRQPEACIAVEEGKDVLIMDLCKDTVPENQEFVLQEDGTLVHK 537

  Fly   633 -ANKC--------DT------------DNRFQQWNF 647
             :.||        ||            ||  |:|.|
  Rat   538 QSGKCVEATEKEFDTSFAPHLRDCSSSDN--QRWLF 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_647749.2	pp-GalNAc-T	205..502	CDD:133004	134/304 (44%)
		beta-trefoil_Ricin_Pgant9-like	515..648	CDD:467340	36/180 (20%)
Galnt12	NP_001413928.1	None