DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant6 and Galnt11

DIOPT Version :9

Sequence 1:	NP_001261342.1	Gene:	Pgant6 / 38346	FlyBaseID:	FBgn0035375	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_001258248.1	Gene:	Galnt11 / 311952	RGDID:	735097	Length:	609	Species:	Rattus norvegicus

Alignment Length:	661	Identity:	227/661 - (34%)
Similarity:	333/661 - (50%)	Gaps:	101/661 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LLISLTLFVLITSWIS----STPYTNKPVH----HGVEPVPEKAGLSGDVKVKVPAIKQPEPQKP 72
            |..|.|..||:..:.:    :.|..|.|:.    ||  |.|:|.         .|...: .|.:.
  Rat    15 LFTSATWTVLLFIYFNFSEVTQPLRNVPIKGSGPHG--PFPKKF---------YPRFTR-GPGRV 67

  Fly    73 QEPDFEEDPELQKIDEPEPVEEEVDNPHPADDEPQQQPQEELQMAAPADASVKKDWHDYTFMEKD 137
            .||.|:.:    ::|  :.:...:::|    |:...:...||.|               .|.|:
  Rat    68 LEPQFKAN----RMD--DLMNNNIEDP----DKGLSKSSSELGM---------------IFNER- 106

  Fly   138 AKRVGLGEGGKASTLDDESQRDLEKRMSLENGFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLP 202
                            |:..|||..:   ::.||.|:|:.:..:|.|||.|:..||.|.|...||
  Rat   107 ----------------DQELRDLGYQ---KHAFNMLISNRLGYHRDVPDTRNAECRGKSYPTDLP 152

  Fly   203 TVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHF-KWVRV 266
            |.||:|.||||..|.|:|:|||:::|:|..|:.|||||||.||.:.|..||:.||..:. ..|:|
  Rat   153 TASVVICFYNEAFSALLRTVHSVVDRTPAHLLHEIILVDDSSDFDDLKGELDEYIQRYLPAKVKV 217

  Fly   267 VRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTN 331
            :|..:|.|||..|..||.:||.|||:|||||.|.|..||.|||..|..:..|.|||.||:|....
  Rat   218 IRNMKREGLIRGRMIGAAHATGEVLVFLDSHCEVNVMWLQPLLAIILEDPHTVVCPVIDIISADT 282

  Fly   332 FHYRAQDEGARGAFDWEFFYKRLPLLPEDLKHPAD----PFKSPIMAGGLFAISREFFWELGGYD 392
            ..| :.....||.|:|...:| ..|:|......||    |.:||.|||||||::|::|.:||.||
  Rat   283 LAY-SSSPVVRGGFNWGLHFK-WDLVPVSDLGGADSATAPIRSPTMAGGLFAMNRQYFNDLGQYD 345

  Fly   393 EGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRVAEVWMD 457
            .|:||||||..|:||:||||||:::..||||:|||:| .|....||...|.:..|..|:|.||:|
  Rat   346 SGMDIWGGENLEISFRIWMCGGKLFIIPCSRVGHIFR-KRRPYGSPEGQDTMTHNSLRLAHVWLD 409

  Fly   458 EYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYP------------ 510
            |||...:|....| ::...|:::|:..:|.||.|:||||:::.|..::..:.|
  Rat   410 EYKEQYFSLRPDL-KTKSFGNISERVELRKKLGCQSFKWYLDNVYPEMQVSGPKARLQQPVFINR 473

  Fly   511 -PVDPPSYAMGALQNVGNQNLCLDTLGR--KKHNKMGMYACADNIKTPQRTQFWELSWKRDLRLR 572
             |..|.....|.|.:: ..|.||...||  :|...:.:.||  :...|  ||.|..:.:.:|.|.
  Rat   474 GPKRPRVLLRGRLYHL-QTNKCLVAQGRSSQKGGLVLLKAC--DYGDP--TQVWIYNEEHELILN 533

  Fly   573 RKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKHGTEGRRCLELLPFSQE---VVAN 634
            ... |||:....::.|..|..||..||:|.|.:. ::.:|...:.| :||.::....:   |...
  Rat   534 NLL-CLDMSETRSSDPPRLMKCHGSGGSQQWTFG-KNNRLYQVSVG-QCLRVVDQMDQKGYVGMA 595

  Fly   635 KCDTDNRFQQW 645
            .||..:. |||
  Rat   596 ICDGSSS-QQW 605

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_001261342.1	BcsA	199..>413	CDD:224136	107/218 (49%)
		pp-GalNAc-T	205..502	CDD:133004	140/301 (47%)
		RICIN	520..647	CDD:238092	37/131 (28%)
		Ricin_B_lectin	520..645	CDD:279046	35/129 (27%)
Galnt11	NP_001258248.1	pp-GalNAc-T	155..453	CDD:133004	140/301 (47%)
		Glyco_tranf_2_3	155..383	CDD:290369	115/230 (50%)
		Ricin_B_lectin	484..605	CDD:279046	35/129 (27%)
		RICIN	488..607	CDD:238092	35/127 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346051
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740