DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pgant6 and Galnt13

DIOPT Version :9

Sequence 1:	NP_001261342.1	Gene:	Pgant6 / 38346	FlyBaseID:	FBgn0035375	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	XP_017447163.1	Gene:	Galnt13 / 311039	RGDID:	735044	Length:	571	Species:	Rattus norvegicus

Alignment Length:	532	Identity:	199/532 - (37%)
Similarity:	300/532 - (56%)	Gaps:	45/532 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 GLGEGGKASTLDDESQRDLEKRMSLENGFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSV 206
            |.||.|||..:..:.|..:::...: |.||.:.||.|::|||:||:|...|:.|.|..:||..||
  Rat    56 GPGEMGKAVLIPKDDQEKMKELFKI-NQFNLMASDLIALNRSLPDVRLEGCKTKVYPDELPNTSV 119

  Fly   207 IIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFKWVRVVRLPR 271
            :|:|:||..|.|:|:|:|:|||||..|:.|:|||||.|:|::|...||.|:......|:::|:..
  Rat   120 VIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKTLEVPVKIIRMEE 184

  Fly   272 RTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRA 336
            |:|||.||..||..:..:|:.|||:|.|....||.|||..|..:::|.|||.||||....|.|.|
  Rat   185 RSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFEYMA 249

  Fly   337 QDEGARGAFDWEFFYKRLPLLPEDL-KHPAD---PFKSPIMAGGLFAISREFFWELGGYDEGLDI 397
            ..:...|.|:|:..::..|:...:: :...|   |.::|.||||||:|.|.:|.|:|.||.|:||
  Rat   250 GSDMTYGGFNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIGTYDAGMDI 314

  Fly   398 WGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRVAEVWMDEYKNY 462
            ||||..|:||:||.|||.:....||.:||::|....:......|..::||.:|:|||||||:|::
  Rat   315 WGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTFPGGTGHVINKNNRRLAEVWMDEFKDF 379

  Fly   463 LYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPPS--YAMGALQNV 525
            .|....|:.: ||.||::.:|.:|..|.||.|.|::|.:       ||....|.  |::|.::||
  Rat   380 FYIISPGVVK-VDYGDVSVRKTLRENLKCKPFSWYLENI-------YPDSQIPRRYYSLGEIRNV 436

  Fly   526 GNQNLCLDTLGRKKHNKMGMYAC----ADNIKTPQRTQFWELSWKRDLRLRRKKECLDVQIWDAN 586
             ..|.|||.:|||::.|:|::.|    .:.:          .|:..|..:|....||||.  ..:
  Rat   437 -ETNQCLDNMGRKENEKVGIFNCHGMGGNQV----------FSYTADKEIRTDDLCLDVS--RLS 488

  Fly   587 APVWLWDCHSQGGNQYWYYDYRHKQLKHGTEGRRCL---ELLPFSQEVVANKCDTDNRFQQWNFG 648
            .||.:..||...|||.|.||.....|.| ...:.||   ::...||.:....|: |:..|:|
  Rat   489 GPVIMLKCHHMRGNQLWEYDAETHTLVH-IITQSCLSMGKVADGSQHLTMETCN-DSTLQKW--- 548

  Fly   649 SFNKTALDNYSQ 660
                 .|.||::
  Rat   549 -----LLRNYTR 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_001261342.1	BcsA	199..>413	CDD:224136	96/217 (44%)
		pp-GalNAc-T	205..502	CDD:133004	128/300 (43%)
		RICIN	520..647	CDD:238092	40/133 (30%)
		Ricin_B_lectin	520..645	CDD:279046	39/131 (30%)
Galnt13	XP_017447163.1	pp-GalNAc-T	118..418	CDD:133004	128/307 (42%)
Galnt13	XP_017447163.1	Ricin_B_lectin	431..548	CDD:395527	39/131 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346057
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740