DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pgant6 and Galnt9

DIOPT Version :9

Sequence 1:	NP_001261342.1	Gene:	Pgant6 / 38346	FlyBaseID:	FBgn0035375	Length:	666	Species:	Drosophila melanogaster
Sequence 2:	NP_938048.2	Gene:	Galnt9 / 231605	MGIID:	2677965	Length:	604	Species:	Mus musculus

Alignment Length:	557	Identity:	189/557 - (33%)
Similarity:	280/557 - (50%)	Gaps:	92/557 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 GLGEGGKASTLDDESQRDLEKRMSLEN-GFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVS 205
            |||:||.|:||.|:||   |.....|: |:||.|||.||::|::||.|...||:..|...||.:|
Mouse    94 GLGQGGVAATLQDDSQ---ETEGKFEDFGYNAQLSDRISLDRTIPDYRPKRCRQITYSEDLPQIS 155

  Fly   206 VIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFK-WVRVVRL 269
            |:.||.||.|||::|||||::|.:|.:|:||:|||||:||...|...|:.|:.:.:. .|:|||.
Mouse   156 VVFIFVNEALSVILRSVHSVVNHTPSQLLKEVILVDDNSDNVELKFNLDQYVHKRYPGLVKVVRN 220

  Fly   270 PRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHY 334
            .||.|||.||..|.:.|||.::.|.|:|||.|..|..|.|..|..::|..:.|.||.|.::.|..
Mouse   221 SRREGLIRARLQGWKVATAPIVGFFDAHVEFNTGWAEPALARIQEDRRRIILPAIDNIKYSTFEV 285

  Fly   335 RAQDEGARGAFDWEFFYKRLPLLPEDLKHPAD---PFKSPIMAGGLFAISREFFWELGGYDEGLD 396
            :.....|.| ::|..:...: :.|:|.....|   |.::|.|.|..|.:.||:|.::|..|.|::
Mouse   286 QQYASAAHG-YNWGLWCMYI-IPPQDWLDRGDESAPIRTPAMIGCSFVVDREYFGDIGLLDPGME 348

  Fly   397 IWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGD---YLHKNYKRVAEVWMDE 458
            ::|.|..||..::|.|||.|...||||:.||.|..:     |...|   |..:|..|.||||||:
Mouse   349 VYGAENIELGMRVWQCGGSMEVLPCSRVAHIERTKK-----PYNNDIDYYAKRNALRAAEVWMDD 408

  Fly   459 YKNYLY--------SHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPP 515
            :|:::|        :.|      ||.||::|:.|:|.||.|:||||::|.| :..|:.|    ..
Mouse   409 FKSHVYMAWNIPMTNPG------VDFGDVSERLALREKLKCRSFKWYLENV-YPEMRIY----NN 462

  Fly   516 SYAMGALQNVGNQNLCLDTLGRKKHNKMGMYAC-----------ADNIKTPQRTQFWELSWKRDL 569
            :...|.::|......|||. |.:..::..:|.|           |:.:     .|...|.....|
Mouse   463 TLTYGEVRNSKASGYCLDQ-GAEDDDRAILYPCHGMSSQLVRYSAEGL-----LQLGPLGSTAFL 521

  Fly   570 ------------RLRRKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKHGTEGRRCL 622
                        |:...|:|.||    |.....||| .:|.|...            ..:..|||
Mouse   522 PDSKCLVDDGRGRMPTLKKCEDV----ARPTQRLWD-FTQSGPIV------------SRDTGRCL 569

  Fly   623 EL-----LPFSQEVVANKCDTDNRFQQWNFGSFNKTA 654
            |:     ..|...:|..:|..    |:|...::.|.|
Mouse   570 EVEMSKDANFGLRLVVQRCSG----QKWMIRNWIKHA 602

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_001261342.1	BcsA	199..>413	CDD:224136	84/217 (39%)
		pp-GalNAc-T	205..502	CDD:133004	122/311 (39%)
		RICIN	520..647	CDD:238092	32/154 (21%)
		Ricin_B_lectin	520..645	CDD:279046	31/152 (20%)
Galnt9	NP_938048.2	pp-GalNAc-T	155..454	CDD:133004	123/312 (39%)
		Ricin_B_lectin	465..593	CDD:279046	31/154 (20%)
		RICIN	467..595	CDD:238092	32/154 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842539
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3736
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830