Protein Alignment Pgant6 and Galnt11

DIOPT Version :10

• Sequence 1: NP_647749.2
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_659157.1
• Gene: Galnt11 / 231050
• MGIID: 2444392
• Length: 608
• Species: Mus musculus
• Alignment Length: 663
• Identity: 225/663 - (33%)
• Similarity: 329/663 - (49%)
• Gaps: 105/663 - (15%)

  Fly    16 LLISLTLFVLITSWIS----STPYTNKPVH----HGVEPVPEKAGLSGDVKVKVPAIKQPEPQKP 72
            |..|.|..||:..:.:    :.|..|.|:.    ||  |.|:|.                .|:..
Mouse    14 LFTSATWTVLLFIYFNFSEVTQPLRNVPIKGSGPHG--PFPKKF----------------YPRFT 60

  Fly    73 QEPDFEEDPELQ--KIDEPEPVEEEVDNPHPADDEPQQQPQEELQMAAPADASVKKDWHDYTFME 135
            :.|....||:.:  :||  ..:...:::|    |:...:...||.|               .|.|
Mouse    61 RGPGRVLDPQFKANRID--RLMNNHIEDP----DKGLSKSSSELGM---------------IFNE 104

  Fly   136 KDAKRVGLGEGGKASTLDDESQRDLEKRMSLENGFNALLSDSISVNRSVPDIRHPLCRKKEYVAK 200
            :                 |:..|||..:   ::.||.|:|:.:..:|.|||.|:..||:|.|...
Mouse   105 R-----------------DQELRDLGYQ---KHAFNMLISNRLGYHRDVPDTRNAECRRKSYPTD 149

  Fly   201 LPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHF-KWV 264
            |||.|::|.||||..|.|:|:|||:::|:|..|:.|||||||.||.:.|..||:.||..:. ..|
Mouse   150 LPTASIVICFYNEAFSALLRTVHSVVDRTPAHLLHEIILVDDSSDFDDLKGELDEYIQRYLPAKV 214

  Fly   265 RVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDH 329
            :|:|..:|.|||..|..||.:||.|||:|||||.|.|..||.|||..|..:..|.|||.||:|..
Mouse   215 KVIRNMKREGLIRGRMIGAAHATGEVLVFLDSHCEVNVMWLQPLLAIILEDPHTVVCPVIDIISA 279

  Fly   330 TNFHYRAQDEGARGAFDWEFFYKRLPLLP-EDLKHP---ADPFKSPIMAGGLFAISREFFWELGG 390
            ....| :.....||.|:|...:| ..|:| .:|..|   ..|.:||.|||||||::|::|.:||.
Mouse   280 DTLAY-SSSPVVRGGFNWGLHFK-WDLVPVSELGGPDGATAPIRSPTMAGGLFAMNRQYFNDLGQ 342

  Fly   391 YDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRVAEVW 455
            ||.|:||||||..|:||:||||||:::..||||:|||:| .|....||...|.:..|..|:|.||
Mouse   343 YDSGMDIWGGENLEISFRIWMCGGKLFILPCSRVGHIFR-KRRPYGSPEGQDTMTHNSLRLAHVW 406

  Fly   456 MDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYP---------- 510
            :||||...:|....| ::...|:::|:..:|.||.|:||||:::.:..::....|
Mouse   407 LDEYKEQYFSLRPDL-KNKSFGNISERVELRKKLGCQSFKWYLDNIYPEMQIPGPNAKPQQPVLI 470

  Fly   511 ---PVDPPSYAMGALQNVGNQNLCLDTLGRKKHNKMGMYACADNIKT---PQRTQFWELSWKRDL 569
               |..|.....|.|.:: ..|.||...||.. .|.|:..    :||   ...||.|..:...:|
Mouse   471 NRGPKRPRVLQRGRLYHL-QTNKCLVAQGRSS-QKGGLVL----LKTCDYGDPTQVWIYNEDHEL 529

  Fly   570 RLRRKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKHGTEGR--RCLELLPFSQEVV 632
            .|.... |||:....::.|..|..||..||:|.|.:. ::.:|...:.|:  |.::|:.....|.
Mouse   530 ILNNLL-CLDMSETRSSDPPRLMKCHGSGGSQQWTFG-KNNRLYQVSVGQCLRVMDLMDQKGYVG 592

  Fly   633 ANKCDTDNRFQQW 645
            ...||..:. |||
Mouse   593 MAICDGSSS-QQW 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_647749.2	pp-GalNAc-T	205..502	CDD:133004	139/301 (46%)
		beta-trefoil_Ricin_Pgant9-like	515..648	CDD:467340	37/136 (27%)
Galnt11	NP_659157.1	Catalytic subdomain A	150..261		59/110 (54%)
		pp-GalNAc-T	154..452	CDD:133004	139/301 (46%)
		Catalytic subdomain B	319..381		39/61 (64%)
		beta-trefoil_Ricin_GALNT11	478..604	CDD:467318	35/134 (26%)