Protein Alignment Pgant6 and Galnt17

DIOPT Version :10

• Sequence 1: NP_647749.2
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_660253.2
• Gene: Galnt17 / 212996
• MGIID: 2137594
• Length: 598
• Species: Mus musculus
• Alignment Length: 493
• Identity: 182/493 - (36%)
• Similarity: 271/493 - (54%)
• Gaps: 24/493 - (4%)

  Fly   142 GLGEGGKASTLDDESQRDLEKRMSLENGFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSV 206
            |.|:||..:|| ..|:.:..|....:.|:|:.||:.||::||:||.|...|::.:|..:||.:|:
Mouse    93 GRGKGGLPATL-SPSEEEKAKGPHEKYGYNSYLSEKISLDRSIPDYRPTKCKELKYSKELPQISI 156

  Fly   207 IIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFK-WVRVVRLP 270
            |.||.||.|||::|||||.:|.:|..|:||||||||:||.|.|...||.|:.:.:. .|:|||..
Mouse   157 IFIFVNEALSVILRSVHSAVNHTPTHLLKEIILVDDNSDEEELKAPLEEYVHKRYPGLVKVVRNQ 221

  Fly   271 RRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYR 335
            :|.|||.||..|.:.||.:|..|.|:|||....|..|:|..|..|::..:.|.||.|...||..:
Mouse   222 KREGLIRARIEGWKAATGQVTGFFDAHVEFTAGWAEPVLSRIQENRKRVILPSIDNIKQDNFEVQ 286

  Fly   336 AQDEGARGAFDWEFF--YKRLPLLPEDLKHPADPFKSPIMAGGLFAISREFFWELGGYDEGLDIW 398
            ..:..|.| :.||.:  |...|....|...|:.|.::|.|.|..|.::|:||.|:|..|.|:|::
Mouse   287 RYENSAHG-YSWELWCMYISPPKDWWDAGDPSLPIRTPAMIGCSFVVNRKFFGEIGLLDPGMDVY 350

  Fly   399 GGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRVAEVWMDEYKNYL 463
            |||..||..|:|:|||.|...||||:.||.|..:.:  :...|.|..:|..||||||||:||:::
Mouse   351 GGENIELGIKVWLCGGSMEVLPCSRVAHIERKKKPY--NSNIGFYTKRNALRVAEVWMDDYKSHV 413

  Fly   464 YSHGDGLYES--VDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKTYPPVDPPSYAMGALQNVG 526
            |...:...|:  :|.||::|:||:|..|.||:|:|:::.| :..|:.|    ..:.|.|.|:|..
Mouse   414 YIAWNLPLENPGIDIGDVSERKALRKSLKCKNFQWYLDHV-YPEMRRY----NNTIAYGELRNNK 473

  Fly   527 NQNLCLDTLGRKKHNKMGMYAC---ADNIKTPQRTQFWELSWKRDLRLRRKKECLDVQIWDANAP 588
            .:::|||....:.|..: :|.|   ...:....:..|..|.......|.....|| |....:..|
Mouse   474 AKDVCLDQGPLENHTAI-LYPCHGWGPQLARYTKEGFLHLGALGTTTLLPDTRCL-VDNSKSRLP 536

  Fly   589 VWLWDCHSQGGNQY--WYYDYRHKQLKHGTEGRRCLEL 624
             .|.||.....:.|  |.:......:..||  .||||:
Mouse   537 -QLLDCDKVKSSLYKRWNFIQNGAIMNKGT--GRCLEV 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_647749.2	pp-GalNAc-T	205..502	CDD:133004	128/301 (43%)
		beta-trefoil_Ricin_Pgant9-like	515..648	CDD:467340	28/115 (24%)
Galnt17	NP_660253.2	Catalytic subdomain A	151..262		56/110 (51%)
		pp-GalNAc-T	155..454	CDD:133004	129/302 (43%)
		Catalytic subdomain B	319..381		30/61 (49%)
		beta-trefoil_Ricin_GALNT17	457..598	CDD:467352	30/124 (24%)