Protein Alignment Pgant6 and gly-5

DIOPT Version :10

• Sequence 1: NP_647749.2
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_001379253.1
• Gene: gly-5 / 176736
• WormBaseID: WBGene00001630
• Length: 626
• Species: Caenorhabditis elegans
• Alignment Length: 672
• Identity: 239/672 - (35%)
• Similarity: 350/672 - (52%)
• Gaps: 94/672 - (13%)

  Fly    11 KASLLLLISLTLFVLITSWISSTPYTNKPVHHGVEPVPEKAGLSGDVKVKVPAIKQPEPQKPQEP 75
            ||.|.:|:.:.:|     ||.|..:.....:..     .:.|.:.|:..|:           .|.
 Worm     7 KAILKVLLLVPVF-----WICSLIFFAATSNDS-----SQIGSNNDLANKI-----------AEA 50

  Fly    76 DFEEDPELQKID---------EPEPVEEEVDNPHPADDEPQQQPQEELQMAAPADASVKKDWHDY 131
            :|.  |:..|.|         |||||.|  :|....:::|.....:...|..|.|...||.
 Worm    51 NFH--PKAAKQDVIQGFGPPIEPEPVVE--NNKVEEEEQPGGNLAKPKFMVDPNDPIYKKG---- 107

  Fly   132 TFMEKDAKRVGLGEGGKASTLD-----DESQRDLEKRMSLENGFNALLSDSISVNRSVPDIRHPL 191
                 ||.:.  ||.|||..:|     .|.:...:|.| |.|.||...||.|||:|::|......
 Worm   108 -----DAAQA--GELGKAVVVDKTKLSTEEKAKYDKGM-LNNAFNQYASDMISVHRTLPTNIDAE 164

  Fly   192 CRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKELETY 256
            |:.::|...||..||||.|:||..|||:|:|||::.|:|..|::|::||||.||.::..:.||.|
 Worm   165 CKTEKYNENLPRTSVIICFHNEAWSVLLRTVHSVLERTPDHLLEEVVLVDDFSDMDHTKRPLEEY 229

  Fly   257 IAEHFKWVRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVC 321
            :::....|:::|:.:|.|||.||..||..||.|||.:||||.|....|:.|||:.|..:..|.||
 Worm   230 MSQFGGKVKILRMEKREGLIRARLRGAAVATGEVLTYLDSHCECMEGWMEPLLDRIKRDPTTVVC 294

  Fly   322 PFIDVIDHTNFHYRAQDE--GARGAFDW--EFFYKRLPLLPEDLKH---PADPFKSPIMAGGLFA 379
            |.|||||...|.|.....  .:.|.|||  :|.:..:|  ..|.|:   |.||.:||.||||||:
 Worm   295 PVIDVIDDNTFEYHHSKAYFTSVGGFDWGLQFNWHSIP--ERDRKNRTRPIDPVRSPTMAGGLFS 357

  Fly   380 ISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKG--- 441
            |.:::|.:||.||.|.||||||..|||||||||||.:...|||.:||::|     :.||.|.
 Worm   358 IDKKYFEKLGTYDPGFDIWGGENLELSFKIWMCGGTLEIVPCSHVGHVFR-----KRSPYKWRTG 417

  Fly   442 -DYLHKNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDL 505
             :.|.:|..|:||||:|:||.|.|...:.  :..|.||::.:|.:|..|.||||||:::.:
 Worm   418 VNVLKRNSIRLAEVWLDDYKTYYYERINN--QLGDFGDISSRKKLREDLGCKSFKWYLDNI---- 476

  Fly   506 MKTYPPVDPP--SYAMGALQNVGNQNL-CLDTL-GRKKHNK-MGMYACADNIKTPQRTQFWELSW 565
               ||.:..|  |.|.|.::|...|.. |||.: ||.:.|: :|.|.|...    ...|:|.||
 Worm   477 ---YPELFVPGESVAKGEVRNSAVQPARCLDCMVGRHEKNRPVGTYQCHGQ----GGNQYWMLS- 533

  Fly   566 KRDLRLRRKKECLDVQIWDANAPVWLWDCHSQGGNQYWYYDYRHKQLKHGTEGRRCLELLPFSQE 630
             :|..:||.:.|:|.    |.:.|.::.||...|||.|.|::...:|:|.. .::||.:.....:
 Worm   534 -KDGEIRRDESCVDY----AGSDVMVFPCHGMKGNQEWRYNHDTGRLQHAV-SQKCLGMTKDGAK 592

  Fly   631 VVANKCDTDNRFQQWNFGSFNK 652
            :....|..|:.:|.|.|..:|:
 Worm   593 LEMVACQYDDPYQHWKFKEYNE 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_647749.2	pp-GalNAc-T	205..502	CDD:133004	139/307 (45%)
		beta-trefoil_Ricin_Pgant9-like	515..648	CDD:467340	41/137 (30%)
gly-5	NP_001379253.1	pp-GalNAc-T	178..477	CDD:133004	139/314 (44%)
		beta-trefoil_Ricin_Pgant9-like	485..610	CDD:467340	40/135 (30%)