Protein Alignment Pgant6 and gly-3

DIOPT Version :10

• Sequence 1: NP_647749.2
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: NP_498722.1
• Gene: gly-3 / 176112
• WormBaseID: WBGene00001628
• Length: 612
• Species: Caenorhabditis elegans
• Alignment Length: 605
• Identity: 207/605 - (34%)
• Similarity: 313/605 - (51%)
• Gaps: 52/605 - (8%)

  Fly    68 EPQKPQEPDFEEDPEL----QKIDEPEPVEEEVDNP--HPADDEPQQQPQEELQMAAPADASVKK 126
            :|...|:..|.||..:    ::|:...|..:...:|  ||.      ||:::.:...|.|.....
 Worm    35 DPSTSQQQPFPEDNRILNRARRIEPLPPAAQHDSDPDAHPI------QPEKQEKQVYPVDKETAN 93

  Fly   127 DWHDYTFMEKDAKRVGL-GEGGKASTLDDESQRDLEKRMSLENGFNALLSDSISVNRSVPDIRHP 190
            ...  ..||..|...|. |:||...|:.::.:...|||. |||.||.:.|:.|||||::||.|..
 Worm    94 QLR--KLMETQAFGPGYHGQGGTGVTVPEDKKTIKEKRF-LENQFNVVASEMISVNRTLPDYRSD 155

  Fly   191 LCR---KKEYVAKLPTVSVIIIFYNEYLSVLMRSVHSLINRSPPELMKEIILVDDHSDREYLGKE 252
            .||   .....|.:|..|:||:|:||..:.|:|::||:|||||..|::|||||||.|||:||.|.
 Worm   156 ACRTSGNNLKTAGMPKTSIIIVFHNEAWTTLLRTLHSVINRSPRHLLEEIILVDDKSDRDYLVKP 220

  Fly   253 LETYIAEHFKWVRVVRLPRRTGLIGARAAGARNATAEVLIFLDSHVEANYNWLPPLLEPIALNKR 317
            |::||......:.:|.|..|:|||.||..|:..|..::|:|||:|||....||.||:..:|.:::
 Worm   221 LDSYIKMFPIPIHLVHLENRSGLIRARLTGSEMAKGKILLFLDAHVEVTDGWLEPLVSRVAEDRK 285

  Fly   318 TAVCPFIDVIDHTNFHYRAQDEGARGAFDWEFFYKRLPLLPEDLKHPAD----PFKSPIMAGGLF 378
            ..|.|.||||....|.|....|...|.|:|...::...:...:|.....    |.::|.:|||||
 Worm   286 RVVAPIIDVISDDTFEYVTASETTWGGFNWHLNFRWYAVPKRELNRRGSDRSMPIQTPTIAGGLF 350

  Fly   379 AISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGGEMYDAPCSRIGHIYRGPRNHQPSPRKGDY 443
            ||.::||:::|.||||:.:||||..|:||::|||||.:...||||:||::|....:.........
 Worm   351 AIDKQFFYDIGSYDEGMQVWGGENLEISFRVWMCGGSLEIHPCSRVGHVFRKQTPYTFPGGTAKV 415

  Fly   444 LHKNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDLTEQKAIRTKLNCKSFKWFMEEVAFDLMKT 508
            :|.|..|.|||||||||.:.|...... .:|:.||::|:|.:|..|.||||||::|.:
 Worm   416 IHHNAARTAEVWMDEYKAFFYKMVPAA-RNVEAGDVSERKKLRETLQCKSFKWYLENI------- 472

  Fly   509 YP--PVDPPSYAMGALQNVGNQNLCLDTLGRKKHNKMGMYAC---ADNIKTPQRTQFWELSWKRD 568
            ||  |:.....::||:.|...:. |:||.|:|.....|:.||   ..|       |.|.|:.|.:
 Worm   473 YPEAPLPADFRSLGAIVNRFTEK-CVDTNGKKDGQAPGIQACHGAGGN-------QAWSLTGKGE 529

  Fly   569 LRLRRKKECLDV-QIWDANAPVWLWDCHSQGGN--QYWYYDYRHKQLKHGTEGRRCLELLPFSQE 630
              :|....||.. .::...:.:.|..|.....|  ..:.:|.:...|.|...| :|  :....|.
 Worm   530 --IRSDDLCLSSGHVYQIGSELKLERCSVSKINVKHVFVFDDQAGTLLHKKTG-KC--VTGADQR 589

  Fly   631 VVANKCDTDNRFQQWNFGSF 650
            |..::|....:.|.|....:
 Worm   590 VTLDECGLGRKDQMWQLEGY 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_647749.2	pp-GalNAc-T	205..502	CDD:133004	129/300 (43%)
		beta-trefoil_Ricin_Pgant9-like	515..648	CDD:467340	32/138 (23%)
gly-3	NP_498722.1	pp-GalNAc-T	173..473	CDD:133004	129/307 (42%)
		beta-trefoil_Ricin_GALNT1-like	481..608	CDD:467311	32/139 (23%)