Protein Alignment Pgant6 and GALNTL5

DIOPT Version :10

• Sequence 1: NP_647749.2
• Gene: Pgant6 / 38346
• FlyBaseID: FBgn0035375
• Length: 666
• Species: Drosophila melanogaster
• Sequence 2: XP_016867282.1
• Gene: GALNTL5 / 168391
• HGNCID: 21725
• Length: 496
• Species: Homo sapiens
• Alignment Length: 347
• Identity: 146/347 - (42%)
• Similarity: 214/347 - (61%)
• Gaps: 10/347 - (2%)

  Fly   159 DLEKRMSLENGFNALLSDSISVNRSVPDIRHPLCRKKEYVAKLPTVSVIIIFYNEYLSVLMRSVH 223
            :|.|.: |:.|||.::|.|:.:.|.|||.|..:|.:|.|.|:|||.|::|.||||..:.|.:::.
Human   145 ELHKEL-LKYGFNVIISRSLGIEREVPDTRSKMCLQKHYPARLPTASIVICFYNEECNALFQTMS 208

  Fly   224 SLINRSPPELMKEIILVDDHSDREYLGKELETYIAEHFKW-VRVVRLPRRTGLIGARAAGARNAT 287
            |:.|.:|...::|||||||.|..:.|.::|: |..|.|:. |:::|..:|.|||.||..||.:|:
Human   209 SVTNLTPHYFLEEIILVDDMSKVDDLKEKLD-YHLETFRGKVKIIRNKKREGLIRARLIGASHAS 272

  Fly   288 AEVLIFLDSHVEANYNWLPPLLEPIALNKRTAVCPFIDVIDHTNFHYRAQDEGARGAFDWEFFYK 352
            .:||:|||||.|.|..||.|||..||.:.:..|||.|||||.....|:.... .||.|||...:|
Human   273 GDVLVFLDSHCEVNRVWLEPLLHAIAKDPKMVVCPLIDVIDDRTLEYKPSPL-VRGTFDWNLQFK 336

  Fly   353 RLPLLPEDLKHP---ADPFKSPIMAGGLFAISREFFWELGGYDEGLDIWGGEQYELSFKIWMCGG 414
            ...:...::..|   ..|.:||.|:||:|||.|.:|.|:|.||:.:|.||.|..|||.:||||||
Human   337 WDNVFSYEMDGPEGSTKPIRSPAMSGGIFAIRRHYFNEIGQYDKDMDFWGRENLELSLRIWMCGG 401

  Fly   415 EMYDAPCSRIGHIYRGPRNHQPSPRKGDYLHKNYKRVAEVWMDEYKNYLYSHGDGLYESVDPGDL 479
            :::..||||:|||.: .:..:||.......| ||.|:..||:||||...:....|| :.|..|::
Human   402 QLFIIPCSRVGHISK-KQTGKPSTIISAMTH-NYLRLVHVWLDEYKEQFFLRKPGL-KYVTYGNI 463

  Fly   480 TEQKAIRTKLNCKSFKWFMEEV 501
            .|:..:|.:|.||||:|:::.|
Human   464 RERVELRKRLGCKSFQWYLDNV 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant6	NP_647749.2	pp-GalNAc-T	205..502	CDD:133004	126/301 (42%)
		beta-trefoil_Ricin_Pgant9-like	515..648	CDD:467340
GALNTL5	XP_016867282.1	pp-GalNAc-T	190..486	CDD:133004	126/301 (42%)